European Psychiatry - Volume 33 - March 2016

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S380 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
and to identify possible risk factors which may be the target of
prevention and treatment approaches.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV93
Prevalence of substance use among
Russian, Somali and Kurdish migrants
in Finland: A population-based study
E. Salama ∗ iemelä Castaneda
1 University of Turku, Psychiatry, Turku, Finland
2 University of Oulu, Department of Clinical Neurosciences,
Rovaniemi, Finland
3 National Institute of Health and Welfare, Helsinki, Finland
∗ Corresponding author.
Introduction Although substance use is a well-known public
health risk factor, European population-based studies reporting the
substance use among adult migrant populations are scarce.
Objectives We aim to: (1) determine the prevalence of alcohol
use, cigarette smoking and consumption cannabis and intravenous
drugs in Russian, Somali and Kurdish migrants in Finland and com-
pare them to those of the Finnish general population; (2) determine
if socio-economic andmigration-related factors are associatedwith
substance use in migrants.
Methods We used data primarily from the Finnishmigrant health
and well-being study. Alcohol use was measured with the AUDIT-C
questionnaire, smoking habits and the lifetime cannabis and intra-
venous drug use were recorded. Age-adjusted prevalence rates
were determined by ethnicity and sex. The associations between
background factors and substance use were analysed using logistic
regression analysis.
Results The prevalence rate of risky drinking is lower and the
proportion of abstainers is higher in migrants than in the gen-
eral population. Current smoking is more common in Russian (31%,
P < 0,05) andKurdish (31%, P < 0,05)migrantmen than in the general
population (21%). Younger age was associated with risky drinking,
socioeconomic disadvantage increased the odd for the daily smok-
ing amongmigrants, andmigration-related factors were associated
with substance use.
Conclusions Migrants report less substance use than the general
population, but acculturation-related factors seem to be associated
with higher levels of substance use among migrants. Substance use
seems to be a gendered phenomenon in migrant populations in
comparison to the general population, where lately the alcohol and
tobacco consumption of women have been growing.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV94
Before and after nalmefene, a case
report
N. Salgado ∗ enavente acías anchez
1 Hospital Dr. Rodriguez Lafora, Psiquiatria, Madrid, Spain
2 Hospital Universitario 12 de octubre, Psiquiatria, Madrid, Spain
∗ Corresponding author.
Introduction Clinical and social improvement after treatment
with nalmefene in an alcoholic 41-year-old male, with history of
dependence during 20 years.
Case report Our patient had been abusing alcohol for almost
20 years with short breaks of abstinence (one month). Before
treatment he made a consumption of 105 g of alcohol per day.
Serological examination showed hepatic alterations (GGT 2115,
ALT 229) and a low amount of platelets (61,000). He also had no
other relevant medical history and other possible clinical diagnoses
were excluded. After a week detoxification program and alcohol
consumption cessation during one month, the analytical values
drastically changed: ALT 35, GGT 275, platelets 222,000.
Discussion Nalmefene is an opioid systemmodulator with antag-
onist activity at the and receptors and partial agonist activity at
the receptor. Nalmefene as-needed has been shown to reduce the
total amount of alcohol consumption and number of heavy drink-
ing days and to improve liver function. The aim of this treatment is
centered in decreasing consumption rather than achieving a total
abstinence.
Conclusions Against other pharmacologic approaches such as
disulfiram an acamprosate, the options that allow acute consump-
tion help patients in controlling drinking rampage and make them
realize they will be able to afford alcohol cessation.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV95
Alcohol use disorder following
traumatic brain injury: Lessons
learned from bench to bedside
G. Santos ∗, C. Lima , J. Vitória
1 Hospital Magalhães Lemos, Psiquiatria, Porto, Portugal
2 Hospital Magalhães Lemos, Psychiatry, Porto, Portugal
∗ Corresponding author.
Introduction and objectives Traumatic brain injury (TBI) can result
in a variety of neuropsychiatric disturbances ranging from subtle
deficits to severe intellectual and emotional disturbances, including
cognitive impairments, mood and psychotic disorders and behav-
ioral disturbances. Alcohol use disorder (AUD) and TBI are closely
related. The reward-mediated behaviors central to alcohol addic-
tion seem to interact with the cognitive dysfunction of TBI. First, a
significant proportion of patients with TBI have a history of alco-
hol abuse. Second, AUD might jeopardize TBI recovery and trigger
or lower seizures threshold. Third, both AUD and TBI share a neg-
ative impact on mental functioning (from memory and cognitive
performance to mood impairment). Finally, there is some limited
and recent evidence that TBI can increase AUD in patients with no
history of substance use prior to the injury, by disrupting incentive-
motivation neurocircuitry.
Methods We aim to present a 27-year-old Portuguese male
patient without prior psychiatric history who developed AUD and
epilepsy after TBI (from a work-related fall).
Results After 3 years of treatment, the patient’s hasn’t achieved
abstinence. His treatment included pharmacological therapy with
mood stabilizers, flufenazine injections and naltrexone, psy-
chotherapy and rehabilitative interventions.
Conclusions Given the sparse knowledge about this dual diagno-
sis, the approach of AUD after TBI is still challenging and the best
treatment remains to be determined. Monitoring alcohol consump-
tion should be considered in all patients presenting with TBI.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV96
Gender differences in the use of
prohibited substances in prison
O. Sanz Garcia ∗, M.P. Iba˜nez , A. Muro
1 Barcelona, Spain
2 Parc Sanitari Sant Joan de Deu, Uhpp-c.P. Brians 1, Sant Esteve de
Sesrovires, Barcelona, Spain
∗ Corresponding author.