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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S375

compulsorily (

n

= 65). The European Addiction Severity Index was

used at baseline and at follow-up to assess socio-demographics

and substance use variables. Regression analysis was conducted to

investigate factors associated with abstinence at six-month follow-

up.

Results

The frequency of use of preferred substance showed

markedly improvement for both voluntary admitted (VA) and

compulsory admitted (CA) patients (61% and 37% respectively) at

follow-up. Seventy-five percent of VA patients using amphetamine

reported improvement compared to 53% of CA patients. At follow-

up, the CA group continued to have a higher rate of injection use.

The CA group had experienced higher rates of overdose the past six

months and lower abstinence rates (24% versus 50%) at follow-up.

Lower severity of drug use at intake (non-injectiondrug use), volun-

tary treatment modality and higher treatment involvement during

follow-up all were significant factors associated with abstinence at

follow-up.

Conclusion

Voluntary treatment for SUD generally yielded better

outcomes; nevertheless we found improved outcomes also for CA

patients. It is important to keep in mind that the alternative to CA

treatment in reality is no treatment at all and instead a continuation

of life-threatening drug use behaviours.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1062

EV78

Cerebellar atrophy supporting

diagnosis of alcohol dependence: A

case report

F. Pavez Reyes

1 ,

, M. Sánchez

1

, E. Moral

1

, M. Terradillos

2

,

N. López

1

, M. Roca

1

, A. García

1

, J. Russo

1

1

Hospital General Universitario Reina Sofía, Psychiatry, Murcia,

Spain

2

Centro de Salud Mental Murcia Este, Psiquiatría, Murcia, Spain

Corresponding author.

Chronic use of alcohol is a known cause of cerebellar atrophy.

This finding could be a valuable diagnosis support when there

are not other information sources. In this case report, we describe

a 65-year-old male patient who was referred from primary care

to specialized consultation because a depressive syndrome it was

unresponsive to treatment with desvenlafaxine and lorazepam.

In psychopathological exploration we found overvalued ideas of

suffering some kind of injury and damage by the family, which

oriented the diagnostic hypothesis of delusional disorder with sec-

ondary mood symptoms, although the clinical suspicion of abuse

of alcohol was proposed as a differential diagnosis. The contin-

uing minimization and denial of consumption by the patient as

well as their reluctance to incorporate an external informant made

that the workup was a key element to elucidate the diagnosis.

We found a discrete increase in transaminases, gamma glutamyl

transferase and alkaline phosphatase. Magnetic resonance imag-

ing showed cerebellar atrophy (vermian and, in a lesser extent, in

both hemispheres). Once the patient was confronted with these

results, he agreed to disclose his problem, which fulfilled alcohol

dependence criteria. After that, he accepted to initiate treatment

and detoxification in a specialized unity.

Conclusions

Although psychiatric diagnosis is based on the clin-

ical features and the exclusion of associated medical conditions,

in this case the workup provided support to our clinical suspicion,

favouring recognition of the problem and willingness to treatment

by the patient.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1063

EV79

Addictive behaviour and bariatric

surgery: Case report and literature

review

F. Pavez

1 ,

, N. López

1

, E. Saura

2

, M. Roca

1

, A. García

1

, J. Russo

1

,

M. Sánchez

1

, E. Moral

1

1

Hospital General Universitario Reina Sofía, Psychiatry, Murcia,

Spain

2

Fundación Jesús Abandonado, Unidad de Asistencia Psicológica,

Murcia, Spain

Corresponding author.

Even though the scientific evidence supports the benefits of

bariatric surgery, its indications and contraindications must be

continually revised in order to avoid psychiatric complications.

Substance use is more common in patients subjected to bariatric

surgery than in the general population. There are reports of

increased incidence of alcohol abuse in patients after bariatric

surgery.

Objective

To review the available evidence, after treat the case

of a 50-year-old man with addiction history whose addictive

behaviour worsened after undergoing bariatric surgery, with

decreased tolerance to alcohol effect and increase of the intake,

as well as changes in the graduation of alcohol used (including

antiseptic). As a result, a dangerous revolving door that led him

to repeated admissions, including Intensive Care Unit.

Results

The case is consistent with the literature that suggests

that there is an increased risk of later alcohol-related problems

after bariatric surgery. This risk is higher several years post surgery,

in patients with previous history of problems related to alcohol,

young, men, and Roux-en-Y Gastric Bypass procedure.

Conclusions

The indications for bariatric surgery should thor-

oughly consider the history of addiction, an adequate assessment of

the patient’s mental status and psychoeducation about the possible

psychiatric side effects, in order to develop preventive strategies.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1064

EV80

Characteristics and outcome of

methadone maintenance treatment

(MMT) patients with depression

E. Peles

, A. Sason , E. Malik , S. Schreiber , M. Adelson

Tel Aviv Medical Center, Adelson Clinic for Drug Abuse Treatment &

Research, Tel Aviv, Israel

Corresponding author.

Introduction

Comorbidity of depression and opioid addiction is

highly prevalent, but their outcome in MMT is not consistent.

Objectives

To compare between depressed and non-depressed

MMT patients.

Methods

Hamilton depression scale scores (taken during a

psychiatric assessment) were studied among MMT patients on

admission or during treatment (cutoff for depression > 18).

Results

A total of 498 MMT patients were studied. Depression

proportion was 22.5%, and 23.2% among 263 who were studied

on admission; the depressed vs. non-depressed on admission did

not differ in female proportion (19.7% vs. 25.6%), age of admis-

sion (43.2

±

10.4), opiate use onset (21.8

±

6.3) and education years

(9.5

±

2.8), but had higher proportion of cocaine (55.7% vs. 35.1%,

P

= 0.005), and benzodiazepine abuse (73.8% vs. 58.4%,

P

= 0.04).

Retention was high and similar (80.3 vs. 82.9%

P

= 0.7) and of those

who stayed one year, cocaine and benzodiazepine were still higher

among the depressed patients (cocaine: 43.8% vs. 23.2%,

P

= 0.03;

BDZ: 61.2% vs. 40%,

P

= 0.01). Compared to the non-depressed,