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S370

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

cannabis use and all symptoms reappeared. Later he achieved

cannabis abstinence again and he got full recovery, then he was

diagnosed from cannabinoid hyperemesis syndrome.

Conclusion

Cannabinoid hyperemesis syndrome is characterized

by recurrent nausea, vomiting and colicky abdominal pain in

patients with long-term cannabis use. These symptoms have been

reported to be alleviated temporarily by taking a hot shower or

more permanently by abstaining from the use of cannabis. The

phenomenon of cannabinoid hyperemesis and clinical diagnosis

remained obscure until recently. For this reason, it is necessary to

take it into account in order to recognize it and help provide these

patients early and better approach.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1048

EV64

The role of personality traits in

initiating and maintaining addictive

behavior

M. Manea

1 ,

, B. Savu

2

1

UMF CLUJ NAPOCA IULIU HATIEGANU, Medical Education,

Cluj-Napoca, Romania

2

UMF CLUJ NAPOCA IULIU HATIEGANU, Psychiatry, Cluj-Napoca,

Romania

Corresponding author.

Introduction

It is well known that certain personality traits are

more linked to drug abuse than others. Psychiatrists aremore likely

to emphasize the importance of impulsivity in the connection with

substance disorders but in the following study we found an impor-

tant percentage of patients that have a substance abusewere linked

to anxiety through impulsiveness as a personality trait.

Objectives

Most youths admitted for a substance abuse are highly

impulsive. Our quest was to differentiate what component of

impulsivitywasmore frequently linked to a substance use disorder.

Methods

In the study were included 50 patients admitted in the

3rd Psychiatric Clinic, Substance Dependences Department, Cluj-

Napoca. For the identification of the drug abused we used the

multitest screening kit in correlation with the results from the

ForensicMedicine Institute of Cluj-Napoca. Each patient completed

the Barratt Impulsivity Scale and the Swedish Universities Scales of

Personality.

Results

High scores on BIS-11 strongly correlated with atten-

tional impulsiveness (Pearson’s

r

correlation = .838) which means

high inattention and cognitive instability this being linked with

anxiety disorders. Cognitive Instability was correlated with Psychic

Trait Anxiety (

r

= 0.29) andMotor Impulsiveness with Somatic Trait

Anxiety (

r

= 0.3). Normal 0 false false false EN-US X-NONE X-NONE.

Conclusions

The underrecognized anxiety disorders in young

adults whom are admitted for an addictive disorder prefrontal cor-

tex is known to be the source of both impulsivity and could be

linked to anxiety as well (valence asymmetry hypothesis). Normal

0 false false false EN-US X-NONE X-NONE.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1049

EV65

Behavioral disorders and new

psychoactive substances abuse, a

French case series

M. Marillier

, A. Batisse , C. Chevallier , S. Djezzar

GH Lariboisière-Fernand Widal, CEIP-Addictovigilance, Paris, France

Corresponding author.

Introduction

Range of drugs has largely increased the past few

years, especially with the emergence of the New Psychoactive Sub-

stances (NPS) sold online. In front of serious risks they cause on

human health, they are more and more regulated by the law.

Objectives

To describe cases of extreme behavioral disorders and

highlight risks of potential forensic complications linked to these

consumptions.

Methods

We present a case series of serious auto or hetero-

aggressive behavioral disorders related to NPS abuse and notified

to the Parisian addictovigilance center.

Results

Twenty cases were identified between 2010 and 2015.

Users were exclusively men, with mean age of 35.5 years (min:

20, max: 51). Synthetic cathinones are the predominant class of

reported NPS (65%). An association between NPS and sexuality is

found in 60% of cases (12); among them cathinones are used by

11 men. We observed 6 deaths among which, 5 were associated to

sexual practice. Two cases of consumptions of cathinones induced

torture and barbarian acts. Concerning aggressive behavioral dis-

orders, we quote 3 cases of hetero-aggressivity (one by stab wound

and 2 others developed an hypersexuality

±

exhibitionism) and 9

cases of auto-aggressivity characterized by genital mutilations (1),

defenestration (3), suicidal attempt (3), and acute psychiatric disor-

der with endangering life (2). Only four cases have been confirmed

by toxicological analysis.

Conclusion

Behavioral disorders inducing forensics complica-

tions exist with NPS and particularly with cathinones. The

problematic is certainly undervalued. A collaboration between

addictovigilance and forensic services has to be improved.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1050

EV66

Early alcohol use as prognostic factor

for severity in dually diagnosed

patients

R. Martinez-Riera , G. Mateu-Codina , A. Farre-Martinez

,

J.L. Perez de Heredia , J. Marti-Bonany , M.G. Hurtado-Ruiz ,

M.T. Campillo-Saenz , R. Sanchez-Gonzalez , N. Ribas-Mu˜noz ,

C. Castillo-Buenaventura , M. Torrens-Melich

INAD, Psychiatry and Drug Abuse, Barcelona, Spain

Corresponding author.

Objectives

Describe the distinguishing characteristics between

patients with early onset of alcohol use (EARLY, age < 15) and late

onset of alcohol use (LATE, age > 16), both affected of acute non-

substance use psychiatric disorders (non-SUD) and any substance

use disorder admitted in a dual diagnosis unit.

Material and methods

Data on demographic, family, and clinical

factors were gathered among subjects admitted to our dual diag-

nosis unit along three years, all of themmeeting DSM-IV criteria of

any non-substance related Axis I or II disorder and comorbid sub-

stance use disorder (SUD). Statistical analysis was performed by

using SPSS program.

Results

We show results of 748 patients (437 of EARLY group

and 311 of LATE group). Predominantly male (73,53%) with a mean

age of 39,60

±

9,7 years. Most prevalent non-SUD psychiatric dis-

orders were psychotic disorder (39,97%) and personality disorder

(39,30%). In our sample, most common substances of abuse were

Alcohol (45,05%) and Cocaine (30,35%). EARLY patients had an

earlier first contact all substances as well as an earlier age of

problematic consumption of cocaine, alcohol, opioids and nicotine;

they also had major prevalence of opioid SUD, sedatives SUD and

amphetamines SUD (see

Tables 1, 2 and 3 ).

Conclusions

Patients who began earlier their consumptions

of alcohol had major prevalence of opioid, sedatives and