European Psychiatry - Volume 33 - March 2016

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S386 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Objective Nicotine dependence is a worldwide health problem
and the second cause of death worldwide. This article aims to
present the improvement in the technique used by us. The results
of the implementation of the treatment program with the use of
varenicline as a specific medicine for nicotine dependence during
admission to a clinic for chemical dependency treatment. We also
demonstrate that this treatment is possible and safe for patients
with comorbid psychiatric disorders and drug use disorders.
Methods Between August 2012 and August 2013, 98 patients
were evaluated in a clinic for psychiatric and drug use treatment
in Rio de Janeiro, Brazil. The treatment consisted of a smoking
cessation therapy concurrently with the psychiatric treatment.
These patients had used pharmacological therapy associated with
intensive cognitive behavioral therapy, occupational therapy and
moderate physical activity. In addition to the associated therapy,
smokingwas limited to three cigarettes daily beginning the first day
of hospitalization. The drug use disorders and psychiatric illnesses
were treated as usual.
Results The patients adhered to the treatment. Hundred percent
of the treatment group were discharged from the clinic such as
tobacco abstainers. The percentage of abstinence in patients after
discharge according to previous assessments (2008–2009) with
follow-up of 18 months was 51%. Results of the current study are
still under evaluation.
Conclusions Behavioral group therapy and physical activities can
be important allies for varenicline. Behavioral changes also exert
great influence in the maintenance of abstinence.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV112
Hereditary influence in alcohol
dependence
J. Teixeira ∗ ereira ota abral Fernandes
1 Centro Hospitalar Psiquiátrico de Lisboa, Lisbon, Portugal
2 Lisbon’s Psychiatric Hospital Center, UTRA, Lisbon, Portugal
∗ Corresponding author.
Introduction Alcohol dependence is one of the psychiatric dis-
orders for which hereditary influence is strongest. In fact, the
importance of genetic factors in transmission of vulnerability to
alcohol dependencewas first described in literaturemany years ago
by psychiatrists who dedicate to its study. That vulnerability may
be explained by an epigenetic model in which biological heredi-
tary factors associate with environmental factors to cause alcohol
dependence.
Objectives Study the influence of genetic factors on alcohol
dependence.
Methods During 4 consecutive months a sample of alcoholic
patients was collected from the Alcohol Treatment Unit of CHPL
(inpatients and outpatients). Biographic data, patient’s psychiatric
diagnosis and family history of alcohol dependence or of depen-
dence of other drugs were recorded.
Results Initial sample included 122 patients. After exclusion of
patients who were also hospitalized in that period, the final sample
included 102 patients (26% female), with a mean age of 48 years
old. Main patients’ diagnosis was alcohol dependence but most of
them (52%) presented psychiatric comorbidity. Most patients (55%)
had family history of alcohol dependence or dependence of other
substances, 26% did not have and 19% did not know. For 61% of
patients, the father and/or mother were the affected relative. Most
patients (61%) who had a family history of alcohol dependence or
dependence of other substances had 2 or more affected relatives.
Conclusions Most patients with alcohol dependence have family
history of alcohol dependence or dependence of other substances,
usually in more than 1 relative, which must be taken in account
during treatment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV113
Treatment of tobacco dependence in
Romanian women – a vulnerable
population that needs a more
personalized approach
L. Trofor ∗, R. Gherghesanu , R. Chirita , A. Trofor
1 Clinic of Psychiatric Diseases, Psychiatry I, Iasi, Romania
2 Clinic of Pulmonary Diseases, Pulmonology I, Iasi, Romania
∗ Corresponding author.
Background Women face unique and greater health risks from
smoking than men and have a different nicotine dependence pat-
tern.
Aim To design a personalized approach for women addressing
Romanian tobacco dependence treatment centers to quit smoking.
Material and methods A group of 68 smoking women received
a 3 months tobacco dependence treatment intervention, consist-
ing of 3 DVD educational sessions, 20minutes each and a face to
face cognitive – behavioral counseling intervention, emphasiz-
ing particularities of tobacco dependence in women (pregnancy
risks, passive smoking, female hormones configuration, nicotinic
receptors interactions, efficacy of nicotine dependence therapy
according to gender, etc.).
Results Females under study were heavy smokers (17.16 ±8.03
SD packs cigarettes/years) with high nicotine dependence scores
(6.52 ±6.03 SD).
Abstinence rate evaluated in end of treatment (3EOT) phase by an
office visit (self-declared abstinence and exhaled carbon monoxide
validation) was 38% and increased at 44.1% at 6 months follow-up
when evaluated by a telephone contact visit (6TCV).
Conclusions Personalized tobacco dependence treatment
approach, focusing on specific women tobacco use concerns
increased abstinence rates, comparatively to previous data in
women not benefiting educational DVD and face to face sessions
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Reference
[1] Trofor L, Barnea E, Bucur D, Miron R, Bodescu M, Chirila C, et al.
Smoking cessation rates in women versus men – outcomes of
a reimbursed tobacco dependence treatment program. P 4462.
ERJ 2014;44(Suppl. 58).
EV114
Cognitive factors in social adaptation
of opium addicts in remission
L. Tursunkhodjaeva ∗ uzaffarova
1 Tashkent, Uzbekistan
2 Tashkent Institute of Physicians’ Post-Graduate Study, Academic
Department of Addiction Medicine and Adolescent Psychopathology,
Tashkent, Uzbekistan
∗ Corresponding author.
Given significant influence of factors contributing or preventing
social adaptation of drug addicts after termination of drug abuse
on the stabilization of remission, their study is quite a challenge.
To study cognitive factors in social adaptation of opium addicts in
remission, a patient’s ability to predict people’s behavior in various
everyday situations, to discern intentions, feelings and emotional
states of a person by non-verbal and verbal expression we used
M. Sullivan’s method in examination of 75 opium addicts at the
Republican Tertiary Detox Center.