European Psychiatry - Volume 33 - March 2016

392 / 812

S388 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV118
Gender characteristics: Behavioral
and socio-demographic profile of
crack users
T.V. Vernaglia ∗ . Cruz . Henriques
1 Federal University of Rio de Janeiro State, UNIRIO, Medical-Surgical
Nursing Department, Rio de Janeiro, Brazil
2 Psychiatric Institute IPUB/UFRJ, Street Drug Progam, PROJAD, Rio de
Janeiro, Brazil
3 State University of Rio de Janeiro, UERJ, Institute of Social Medicine,
Rio de Janeiro, Brazil
∗ Corresponding author.
Background The increase of crack use has been a challenge for
public health in Brazil. In this context, few studies focus on differ-
ence in abuse of this substance between women and men.
Aims To compare socioeconomic, family relationship and ser-
vice use characteristics crack users in both sexes in out-treatment
patients in Brazil.
Methods A multicentric cross-sectional study was conduct in 6
Brazilian cities. A total of 900 crack users were selected. A Addiction
Severity Index – 6 (ASI-6) questionnaire was applied. It was made
a Chi2 test to identify differences in frequency.
Results The most areas of ASI showed difference. The
women have poor safety conditions than men: unemploy-
ment (69.2% × 49.0%); no money for housing or clothing
(74.64% × 57.56%); without income (66.89%× 40.56%); most illiter-
ate (23.27% ×13.55%); live with their children (31.21% × 14.33%);
difficulty of dealing with their children (18.25% ×5.09%); are
investigated by Council of Guardianship (33.33% ×7.45%); sexual
abuse (33.97% × 8.71%).
Conclusion The woman crack user is more vulnerable than man.
These difficulties could decrease the success rate of rehab. The
knowledge about this vulnerable situation in woman user could
help the health professional to offer support in this fields.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV119
Changes in qualified detoxification
treatment of inpatients with multiple
substance use: Impacts on key figures,
a pre-post-study in an open door unit
in Saxony, Germany
B.S. Voigtlaender ∗, J. Schneider , H. Groß , T. Barth
Klinikum Chemnitz gGmbH, Psychiatry-Behavioural Medicine and
Psychosomatics, Chemnitz, Germany
∗ Corresponding author.
Introduction Detoxification treatment of adults at younger
ages suffering from polysubstance dependence on our depart-
ment pursues an integrative therapeutic concept. In addition to
addiction-specific, topic-centred group and talk therapy orienta-
tion also behavioural therapy elements are included: a penalty
points system provides negative sign stimuli for undesirable
behaviour.
Objectives Since 2010, both rate of psychotic disorders and num-
ber of N-methylamphetamine consumers (P < 0.001) have been
growing impressively while the proportion of repeated admissions
amounted to > 55%. Dissatisfying trends were identified by longi-
tudinal measurement, e.g. regarding ALOS, kind of discharge, bed
occupancy.
Aims Targeted changes in treatment were established in the 2nd
half of 2014. In particular, the penalty point system was adapted
towards less restrictive rules, combined with slightly reduced ther-
apeutic intensity in order to come better on the disorder-related
needs of the patients. Staffing level and structure remained stable.
Methods Key figures including quality criteria and performance
data such as LOS, kind of admission and discharge, service intensity,
and bed occupancywere evaluated by a pre-post study (pre: 1st half
of 2014, N= 76/post: 1st half of 2015, N= 77) using descriptive and
test statistics.
Results Socio-demographic patient data remained stable.
Regarding selected key figures there were significant changes
(LOS > 21 days: P < 0.05; bed occupancy: P < 0.001; therapeutic
contacts < 25min: P < 0.001) and positive trends, e.g. decreased
ratio of non-regular discharges.
Conclusions Our data suggest that punishment-oriented inter-
ventions impede addressing specific needs of inpatients with
multiple substance use whereas more need-oriented interventions
may lead to improvements. Further evaluation including patient
satisfaction is indispensable.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV120
Decrease of velocity and acceleration
of fast eye movement after the
administration of methadone
P. Walecki ∗, E. Gorzelanczyk , J. Feit , M. Kunc
1 Jagiellonian University Medical College, Department of
Bioinformatics and Telemedicine, Kraków, Poland
2 Nicolaus Copernicus University in Torun, Collegium Medicum,
Bydgoszcz, Poland
3 Airedale NHS Trust, Faculty of Medicine, Steeton, United Kingdom
∗ Corresponding author.
Aims The goal of this study is to assess the differences in peak
and medium velocity, peak and medium acceleration of eyeball
movements after the administration of methadone.
Materials and methods Twenty-eight opioid addicts were exam-
ined. Patients admitted oculomotor impaired were excluded.
In this study, we made use of the Saccadometer Advanced
(Advanced Clinical Instrumentation, Cambridge, UK), allowing
the measurement of eye position with the time resolution of
1msec (1000Hz). The eye movement measurement is automated
and synchronised with stimuli presentation. Before and after the
administration of methadone two saccadic tests were carried out:
Prosaccades Test (PT) and Antisaccades Test (AT).
Results The average of peak andmediumvelocity and the average
of peak and medium acceleration of eyeball movements in the test
AT were lower than in the PT test. After administration of a sin-
gle dose of methadone the peak and medium velocity, peak and
medium acceleration decreased in both tests (PT and AT). After
administration of methadone prolonged the duration of saccades,
and prolonged the duration of rising and falling slope of saccades.
Conclusion It was found that methadone ( -opioid receptor ago-
nist) is associated with change of velocity and acceleration of
eyeball movements.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.