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S388

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1102

EV118

Gender characteristics: Behavioral

and socio-demographic profile of

crack users

T.V. Vernaglia

1 ,

, M .S

. Cruz

2 , T.L

. Henriques

3

1

Federal University of Rio de Janeiro State, UNIRIO, Medical-Surgical

Nursing Department, Rio de Janeiro, Brazil

2

Psychiatric Institute IPUB/UFRJ, Street Drug Progam, PROJAD, Rio de

Janeiro, Brazil

3

State University of Rio de Janeiro, UERJ, Institute of Social Medicine,

Rio de Janeiro, Brazil

Corresponding author.

Background

The increase of crack use has been a challenge for

public health in Brazil. In this context, few studies focus on differ-

ence in abuse of this substance between women and men.

Aims

To compare socioeconomic, family relationship and ser-

vice use characteristics crack users in both sexes in out-treatment

patients in Brazil.

Methods

A multicentric cross-sectional study was conduct in 6

Brazilian cities. A total of 900 crack users were selected. A Addiction

Severity Index – 6 (ASI-6) questionnaire was applied. It was made

a Chi

2

test to identify differences in frequency.

Results

The most areas of ASI showed difference. The

women have poor safety conditions than men: unemploy-

ment (69.2%

×

49.0%); no money for housing or clothing

(74.64%

×

57.56%); without income (66.89%

×

40.56%); most illiter-

ate (23.27%

×

13.55%); live with their children (31.21%

×

14.33%);

difficulty of dealing with their children (18.25%

×

5.09%); are

investigated by Council of Guardianship (33.33%

×

7.45%); sexual

abuse (33.97%

×

8.71%).

Conclusion

The woman crack user is more vulnerable than man.

These difficulties could decrease the success rate of rehab. The

knowledge about this vulnerable situation in woman user could

help the health professional to offer support in this fields.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1103

EV119

Changes in qualified detoxification

treatment of inpatients with multiple

substance use: Impacts on key figures,

a pre-post-study in an open door unit

in Saxony, Germany

B.S. Voigtlaender

, J. Schneider , H. Groß , T. Barth

Klinikum Chemnitz gGmbH, Psychiatry-Behavioural Medicine and

Psychosomatics, Chemnitz, Germany

Corresponding author.

Introduction

Detoxification treatment of adults at younger

ages suffering from polysubstance dependence on our depart-

ment pursues an integrative therapeutic concept. In addition to

addiction-specific, topic-centred group and talk therapy orienta-

tion also behavioural therapy elements are included: a penalty

points system provides negative sign stimuli for undesirable

behaviour.

Objectives

Since 2010, both rate of psychotic disorders and num-

ber of N-methylamphetamine consumers (

P

< 0.001) have been

growing impressively while the proportion of repeated admissions

amounted to > 55%. Dissatisfying trends were identified by longi-

tudinal measurement, e.g. regarding ALOS, kind of discharge, bed

occupancy.

Aims

Targeted changes in treatment were established in the 2nd

half of 2014. In particular, the penalty point system was adapted

towards less restrictive rules, combined with slightly reduced ther-

apeutic intensity in order to come better on the disorder-related

needs of the patients. Staffing level and structure remained stable.

Methods

Key figures including quality criteria and performance

data such as LOS, kind of admission and discharge, service intensity,

and bed occupancywere evaluated by a pre-post study (pre: 1st half

of 2014, N= 76/post: 1st half of 2015, N= 77) using descriptive and

test statistics.

Results

Socio-demographic patient data remained stable.

Regarding selected key figures there were significant changes

(LOS > 21 days:

P

< 0.05; bed occupancy:

P

< 0.001; therapeutic

contacts < 25min:

P

< 0.001) and positive trends, e.g. decreased

ratio of non-regular discharges.

Conclusions

Our data suggest that punishment-oriented inter-

ventions impede addressing specific needs of inpatients with

multiple substance use whereas more need-oriented interventions

may lead to improvements. Further evaluation including patient

satisfaction is indispensable.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1104

EV120

Decrease of velocity and acceleration

of fast eye movement after the

administration of methadone

P. Walecki

1 ,

, E. Gorzelanczyk

2

, J. Feit

2

, M. Kunc

3

1

Jagiellonian University Medical College, Department of

Bioinformatics and Telemedicine, Kraków, Poland

2

Nicolaus Copernicus University in Torun, Collegium Medicum,

Bydgoszcz, Poland

3

Airedale NHS Trust, Faculty of Medicine, Steeton, United Kingdom

Corresponding author.

Aims

The goal of this study is to assess the differences in peak

and medium velocity, peak and medium acceleration of eyeball

movements after the administration of methadone.

Materials and methods

Twenty-eight opioid addicts were exam-

ined. Patients admitted oculomotor impaired were excluded.

In this study, we made use of the Saccadometer Advanced

(Advanced Clinical Instrumentation, Cambridge, UK), allowing

the measurement of eye position with the time resolution of

1msec (1000Hz). The eye movement measurement is automated

and synchronised with stimuli presentation. Before and after the

administration of methadone two saccadic tests were carried out:

Prosaccades Test (PT) and Antisaccades Test (AT).

Results

The average of peak andmediumvelocity and the average

of peak and medium acceleration of eyeball movements in the test

AT were lower than in the PT test. After administration of a sin-

gle dose of methadone the peak and medium velocity, peak and

medium acceleration decreased in both tests (PT and AT). After

administration of methadone prolonged the duration of saccades,

and prolonged the duration of rising and falling slope of saccades.

Conclusion

It was found that methadone ( -opioid receptor ago-

nist) is associated with change of velocity and acceleration of

eyeball movements.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1105