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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S72–S115

S97

medication, in the current episode. Patients with bipolar depres-

sive disorder, MDD with psychotic and atypical features, other

psychiatric disorders, sever medical condition, acute suicidality

and pregnancy were excluded. All patients received stable drug

regimens for at least two weeks before enrollment and drug

dosages remained unchanged throughout the study. They revised

8 stimulation sessions, using a 2mA current, for 20minutes, in 8

consecutive days. The anodal electrode was placed over the left

DLPFC. Cathode electrode over the right supraorbital region. Mood

was evaluated with 21-item Hamilton Rating Depression Scale and

the Beck Depression Inventory.

We designed a pretest–posttest study and evaluate depression at

baseline (pre-intervention), immediately after 8 sessions (post-

intervention) and two months after treatment onset (follow-up).

Results

There is a significant difference between Pre- vs. post-

intervention (F

BDI

= 246.58,

P

< 0.001; F

HRSD

= 214.56,

P

< 0.001)

and pre vs. Follow-up intervention (F

BDI

= 323.10,

P

< 0.001;

F

HRSD

= 150.96,

P

< 0.001).

Conclusion

It can be said that tDCS had effective and enduring

variation (

P

post vs. follow-up

> 0.05) in improving the clinical symp-

toms of MDD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.064

FC61

Cryostimulation of whole body as a

possible supportive biological

approach in mild cognitive

impairments

J. Rymaszewska

, D. Szczesniak , U. Katarzyna , T. Elzbieta ,

S. Bartlomiej

Wroclaw Medical University, Division of Consultation Psychiatry and

Neuroscience, Wroclaw, Poland

Corresponding author.

Background

Limitations of available treatment methods of

dementia imply constant need to search for new, supplemen-

tary therapy strategies. There is a consensus that vascular

lesions, oxidative stress, inflammatory processes and abnormal

neurotransmission are associated with dementia. Due to the

anti-inflammatory (modification of pro-inflammatory cytokines

concentration), antioxidative effect of cryogenic temperatures as

well as the hormonal and lipid changes, theymay play an important

role in preventing or inhibiting pathophysiological processes.

Aim

To assess the influence of whole-body cryostimulation on

cognitive functions of patients with MCI.

Methods

RCT design is used to examine the influence of

whole-body cryotherapy (WBC) on people with mild cognitive

impairments (MCI) with the evaluation of psychometric, somatic

and laboratory parameters. Participants undergo 10 sessions each

day of 2–3min of WBC in experimental group (

110 till

160

C)

and placebo (

20

C). The CDR, MoCA, TYM, DemTect and SLUMS

scales are used among others at baseline and follow-up. Prelimi-

nary data of 7 volunteers (

n

= 7, 49–79 years old) were presented.

Results on

Fig. 1 .

Discussion

Among obtained psychometric results show that all,

except of one, patients significantly improved their scores after

WBC. That is a very promising feedback for future evaluation of

WBC effectiveness in prevention of dementia in patients with MCI.

Fig. 1

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.065

Schizophrenia

FC62

Clinical symptomatology and facial

emotion recognition in

schizophrenia: Which relationship?

A. Arous

, J. Mrizak , R. Trabelsi , A. Aissa , H. Ben Ammar ,

Z. El Hechmi

Razi Hospital, Department Psychiatry F, Tunis, Tunisia

Corresponding author.

Introduction

Patients with schizophrenia show impairments in

social cognitive abilities, such as recognizing facial emotions.

However, the relationships between specific deficits of emotion

recognition and with clusters of psychotic remain unclear.

Objectives

To explore whether facial emotion recognition was

associated with severity of symptoms and to which presentation

of psychotic symptoms.

Methods

Facial emotion recognition (FER) were evaluated in 58

patients with stable schizophrenia with a newly validated FER task

constructed from photographs of the face of a famous Tunisian

actress representing the Ekman’s six basic emotions (happiness,

anger, disgust, sadness, fear, and surprise). Symptomatology evalu-

ation comprised the Positive andNegative Syndrome Scale (PANSS),

the Calgary Depression Scale for Schizophrenia (CDSS) and the Clin-

ical Global Impressions Scale Improvement and severity (CGI).

Results

Patients who failed to identify anger had significantly

higher scores in hyperactivity item (

P

< 0.0001). The patients who

had a difficulty to identify sadness hadmore grandiosity (

P

0.002).

The impairment in happiness recognition was correlated with hal-

lucination (

P

= 0.007) and delusion (

P

= 0.024) items. Incapacity

to identify fear was associated to lack of judgment and insight

(

P

= 0.004).