European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S72–S115 S97
medication, in the current episode. Patients with bipolar depres-
sive disorder, MDD with psychotic and atypical features, other
psychiatric disorders, sever medical condition, acute suicidality
and pregnancy were excluded. All patients received stable drug
regimens for at least two weeks before enrollment and drug
dosages remained unchanged throughout the study. They revised
8 stimulation sessions, using a 2mA current, for 20minutes, in 8
consecutive days. The anodal electrode was placed over the left
DLPFC. Cathode electrode over the right supraorbital region. Mood
was evaluated with 21-item Hamilton Rating Depression Scale and
the Beck Depression Inventory.
We designed a pretest–posttest study and evaluate depression at
baseline (pre-intervention), immediately after 8 sessions (post-
intervention) and two months after treatment onset (follow-up).
Results There is a significant difference between Pre- vs. post-
intervention (FBDI = 246.58, P< 0.001; FHRSD = 214.56, P < 0.001)
and pre vs. Follow-up intervention (FBDI = 323.10, P < 0.001;
FHRSD = 150.96, P < 0.001).
Conclusion It can be said that tDCS had effective and enduring
variation (P post vs. follow-up > 0.05) in improving the clinical symp-
toms of MDD.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
FC61
Cryostimulation of whole body as a
possible supportive biological
approach in mild cognitive
impairments
J. Rymaszewska∗, D. Szczesniak , U. Katarzyna , T. Elzbieta ,
S. Bartlomiej
Wroclaw Medical University, Division of Consultation Psychiatry and
Neuroscience, Wroclaw, Poland
∗ Corresponding author.
Background Limitations of available treatment methods of
dementia imply constant need to search for new, supplemen-
tary therapy strategies. There is a consensus that vascular
lesions, oxidative stress, inflammatory processes and abnormal
neurotransmission are associated with dementia. Due to the
anti-inflammatory (modification of pro-inflammatory cytokines
concentration), antioxidative effect of cryogenic temperatures as
well as the hormonal and lipid changes, theymay play an important
role in preventing or inhibiting pathophysiological processes.
Aim To assess the influence of whole-body cryostimulation on
cognitive functions of patients with MCI.
Methods RCT design is used to examine the influence of
whole-body cryotherapy (WBC) on people with mild cognitive
impairments (MCI) with the evaluation of psychometric, somatic
and laboratory parameters. Participants undergo 10 sessions each
day of 2–3min of WBC in experimental group (−110 till −160◦ C)
and placebo (−20 ◦ C). The CDR, MoCA, TYM, DemTect and SLUMS
scales are used among others at baseline and follow-up. Prelimi-
nary data of 7 volunteers (n = 7, 49–79 years old) were presented.
Results on
Discussion Among obtained psychometric results show that all,
except of one, patients significantly improved their scores after
WBC. That is a very promising feedback for future evaluation of
WBC effectiveness in prevention of dementia in patients with MCI.
Fig. 1
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Schizophrenia
FC62
Clinical symptomatology and facial
emotion recognition in
schizophrenia: Which relationship?
A. Arous∗, J. Mrizak , R. Trabelsi , A. Aissa , H. Ben Ammar ,
Z. El Hechmi
Razi Hospital, Department Psychiatry F, Tunis, Tunisia
∗ Corresponding author.
Introduction Patients with schizophrenia show impairments in
social cognitive abilities, such as recognizing facial emotions.
However, the relationships between specific deficits of emotion
recognition and with clusters of psychotic remain unclear.
Objectives To explore whether facial emotion recognition was
associated with severity of symptoms and to which presentation
of psychotic symptoms.
Methods Facial emotion recognition (FER) were evaluated in 58
patients with stable schizophrenia with a newly validated FER task
constructed from photographs of the face of a famous Tunisian
actress representing the Ekman’s six basic emotions (happiness,
anger, disgust, sadness, fear, and surprise). Symptomatology evalu-
ation comprised the Positive andNegative Syndrome Scale (PANSS),
the Calgary Depression Scale for Schizophrenia (CDSS) and the Clin-
ical Global Impressions Scale Improvement and severity (CGI).
Results Patients who failed to identify anger had significantly
higher scores in hyperactivity item (P < 0.0001). The patients who
had a difficulty to identify sadness hadmore grandiosity (P ≤ 0.002).
The impairment in happiness recognition was correlated with hal-
lucination ( P= 0.007) and delusion (P = 0.024) items. Incapacity
to identify fear was associated to lack of judgment and insight
(P = 0.004).