Table of Contents Table of Contents
Previous Page  515 / 812 Next Page
Information
Show Menu
Previous Page 515 / 812 Next Page
Page Background

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S511

Aims

The aim of the present study was to investigate the preva-

lence of major depression across a sample of Iranian community

pharmacists.

Methods

One hundred and eighty surveys were distributed

among community pharmacists attending different continuous

medical education programs from all over the country during

winter 2015. Beck Depression Inventory was used to measure

characteristic attitudes and symptoms of depression. Descriptive

statistics were utilized to find prevalence of mild, moderate or

severe depression among the study sample. Independent sample

t

-

testswere used to find possible differences between age and gender

of the respondents and prevalence of depression.

Results

Survey response rate was calculated to be 84.7%. Accord-

ing to the results, 72.7% of the respondents were categorized to be

normal, whereas 12.8% were found to have mild, 11.7% moderate,

and 2.8% severe depression. Moreover, no significant relation-

ship was found between age of the respondent and prevalence

of depression (

P

> 0.05). However, the prevalence was found to be

higher among females (

P

< 0.001).

Conclusions

Prevalence of depression among community phar-

macists was reported to be low. However, it may affect healthcare

services that they provide in the healthcare system. Further studies

with larger sample size are suggested.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1491

EV507

Depression and its correlation with

the risk of cardiovascular mortality in

primary care population in Latvia

R. Ivanovs

1 ,

, M. Trapencieris

2

, J. Vrublevska

3

, R. Logins

4

,

L. Berze

4

, E. Rancans

3

1

Riga, Latvia

2

University of Latvia, Institute of Philosophy and Sociology, Riga,

Latvia

3

Riga Stradins University, Department of Psychiatry and Narcology,

Riga, Latvia

4

Riga Stradins University, Department of Continuing Education, Riga,

Latvia

Corresponding author.

Introduction

Depression is one of several preventable causes of

disability worldwide, with coronary heart disease (CHD) being the

largest cause of disability. Depression has been confirmed as a risk

factor for CHD.

Objectives

Few studies tried to find an interrelation between

depression and a risk of cardiovascular mortality according to sys-

tematic coronary risk evaluation (SCORE) chart.

Aims

The aim of study was to examine the correlation of depres-

sion with the risk of cardiovascular mortality (SCORE).

Methods

Study was conducted in 2015 within the framework of

National Research Programme BIOMEDICINE. All patients aged 18

and older at 24 primary care facilities were interviewed with a

sociodemographic questionnaire supplemented by measurements

of blood pressure and total cholesterol. Within 2 weeks after the

visit psychiatrist administered the Mini International Neuropsy-

chiatric Interview (MINI) by telephone. SCORE was assessed using

high risk chart.

Results

Totally 920 patients age 40–69 were included in the data

analysis. According to the MINI 9.3%(95%CI 7.5–11.5%) of 40–69

years old patients had current depression. Current depression was

more common among women than men, 10.4% and 6.8%, respec-

tively. The prevalence of current depression was highest among

patients with SCORE 3–4%. Multivariate logistic regression did not

suggest statistically significant odds ratio for having depression

based on SCORE.

Conclusions

Only one of the measurements used for SCORE

(smoking status) was significant predictor for having current

depression, while systolic blood pressure and total cholesterol were

not significant predictors for depression. As pharmacotherapies

for reducing blood pressure and cholesterol are widely used by

patients further research should include use of these medicines as

potential mediators.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1492

EV508

Energy drinks changed the treatment

of antidepressant drugs

C¸ . Macit

1

, B. Kadıo˘glu

1

, G. Dalan

2

, M. Maassarani

2

, E. Yönel

3

,

T. C¸ elik

1 ,

1

Yeditepe University, School of Pharmacy-Department of

Pharmacology, Istanbul, Turkey

2

Yeditepe University, School of Pharmacy, Istanbul, Turkey

3

Yeditepe University, School of Pharmacy- Department of Clinical

Pharmacy, Istanbul, Turkey

Corresponding author.

Introduction

The increasing use of antidepressants (ADS)

whether it is for the management of depression or off-label use

is apparent and it is important to have a closer look on the possi-

ble effects that accompany the use of ADS with other neurotonic

agents, such as the ones found in energy drinks(ED). ED pose a

threat on public health since they can be consumed by everyone

with no limitations.

Aims

We investigated the unknown interaction that might occur

when ADS are used in combination with ED.

Methods

The effect of both low (4 mL/kg) and high (12 mL/kg)

EDdoses onmice treatedwith an ADS (citalopram15mg/kg, IP) and

non-treated were investigated after acute exposure and 14 days of

chronic exposure. The changes that resulted from performing the

Locomotor Activity test (LMA) and the Porsolt’s Forced Swim test

(FST) were recorded.

Results

The administration of both low and high energy drink

dose resulted in significant impairments in LMA of mice. High dose

ED showed a significant increase in the immobility time in FST.

Mice treated with citalopram resulted in a decrease in the immo-

bility timewhen compared tomice administered only saline and/or

to mice exposed to ED. However, for the mice that were exposed

to both low and high dose ED, citalopram administration did not

significantly decrease their immobility time.

Conclusion

High dose energy drink caused an increase in the

immobility time in FST. Concomitant use of citalopram and ED

decreased the antidepressant effect of citalopram. Thereby patients

using ED with ADS may encounter insufficient drug therapy.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1493

EV509

Dermatological manifestations in

pregnancy with primary psychiatric

findings

A. Wahab

1 ,

, N .

Kalar

2 , F. H

assan

3 , M.

Alzaabi

4 , K. H

ira Bibi

5 ,

A. Jamal

6

, M.U. Kalar

7

, G. Wahab

8

, T. Usman

9

, M.O. Suriya

10

,

E. Mujeeb

11

1

Karachi Medical and Dental College- Abbasi Shaheed Hospital,

Department of Gynecology and Obstetrics, Karachi, Pakistan

2

Department of Obstetrics and Gynecology, Singleton Hospital, South

Wales, Sketty Swansea, UK

3

Department of Medicine, Department of Medicine, Karachi Karachi

Medical & Dental College, Abbasi Shaheed Hospital, Karachi, Pakistan