Table of Contents Table of Contents
Previous Page  519 / 812 Next Page
Information
Show Menu
Previous Page 519 / 812 Next Page
Page Background

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S515

Aim

. The program was addressed to three groups of patients

with burnout, infertility, and social relationship/loneliness crisis.

Method

Using the new stress reduction program (SRP), engag-

ing both pharmacological and psychotherapeutic approach, and

also several lifestyle factors, like physiotherapy, nutrition aspects,

coaching, social media contact and monitoring, most of patients

improved in terms of emotional and behavioral markers, in short-

and long-term (4–6 months) observations.

Material

Patients and clients (N43) with F3.x-F4.x disorders

according to ICD-10.

Results

A variety of PRS scales were used to assess patients’

improvement outcomes. Significant reductions (4–6 months) were

observed at Maslach Burnout Inventory (–23.4%,

P

= 0.000), Fertility

Problem Inventory (–34.5%,

P

= 0.000), UCLA Loneliness Scale, ver.

3 (–43.3%,

P

= 0.000), and Perceived Stress Scale (44.0%,

P

= 0.000).

Discussion

This program interplays between stress and mental

health problems and opens up new possibilities for diagnosis and

therapy, focusing on the challenges of civilization, and especially

opens up preventive options in stress-related problems and dis-

eases, which represent a growing health burdens inmodern society.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1503

EV519

Metabolic dysregulation as predictor

for the course of late-life depression

R. Marijnissen

1 ,

, N. Vogelzangs

2

, M. Mulder

3

, R. van den Brink

4

,

H. Comijs

2

, R. Oude Voshaar

4

1

Wolfheze, Netherlands

2

VU University Medical Center, Department of

Psychiatry/GGZinGeest & Institute for Extramural Medical Research

EMGO, Amsterdam, Netherlands

3

Arnhem, Netherlands

4

University Medical Center Groningen- University of Groningen,

University Center of Psychiatry & Interdisciplinary Center for

Psychopathology of Emotion Regulation, Groningen, Netherlands

Corresponding author.

Introduction

Depression is associated with the metabolic syn-

drome (MS). Recently, the concept of ‘metabolic depression’ has

been proposed based on a protracted course of depressive symp-

toms over time.

Objective and aims

Within the Netherlands study of depression

in older persons, we examined whether metabolic dysregulation

predicted the two-year course of depression.

Methods

A cohort study (

n

= 285) of depressed persons (

60

years) with two-year follow up. Depression was classified accord-

ing to the Diagnostic and Statistical Manual of Mental Disorders,

Fourth Edition (DSM-IV). Severity of depression was assessed with

sum score as well as subscale scores of the Inventory of Depres-

sive Symptomatology (IDS) at six-month intervals. The metabolic

syndrome was defined according the National Cholesterol Educa-

tion Program (NCEP-ATP III). We applied logistic regression and

linear mixed models adjusted for a wide range of confounders and

severity of depression at baseline.

Results

The number of MS-components predicted non-remission

at two-years (OR = 1.28 [95% CI: 1.00–1.58],

P

= 0.047), which

was driven by waist-circumference, HDL-cholesterol and triglyc-

erides. MS was only associated with the somatic symptom

subscale score of the IDS over time, but not with its sum score

(interaction time

×

somatic subscale,

P

= 0.002). This effect was

driven by waist circumference, elevated fasting glucose level and

hypertension.

Conclusion

Metabolic dysregulation predicts the course of late-

life depression. This effect seems to be driven by visceral obesity

(as indicated by the waist circumference) and lipid dysregulations

and with respect to the somatic symptoms of depression.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1504

EV520

The role of self-compassion in lifetime

history of depression: A study in

Portuguese pregnant women

E. Bento

1 , S. X

avier

1 , J. A

zevedo

1 , M.

Marques

1 , 2 , M .J

. Soares

1 ,

M.J. Martins

1 , 3 ,

, P. Castilho

3

, N. Madeira

2

, A. Macedo

1 , 2

,

A.T. Pereira

1

1

Faculty of Medicine-University of Coimbra, Department of

Psychological Medicine, Coimbra, Portugal

2

Coimbra Hospital and University Centre-Portugal, Psychiatry,

Coimbra, Portugal

3

Faculty of Psychology and Educational Sciences - University of

Coimbra, CINEICC, Coimbra, Portugal

Corresponding author.

Introduction

Although self-compassion has been pointed as an

effective strategy for coping with depression, there are not any

studies investigating its associationwith lifetime history of depres-

sion (LTHD).

Objective

To compare self-compassion levels in pregnant women

with vs. without LTHD and to analyze if self-compassion dimen-

sions are significant predictors of LTHD.

Methods

Four hundred and twenty-seven pregnant women with

a mean age of 33 years (

±

4.785) in their second trimester of preg-

nancy completed the Self Compassion Scale validated for pregnancy

(SCS; Bento et al., 2015) and a new self-report questionnaire to

evaluate the presence of LTHD according to DSM-5 criteria for

depression.

Results

Ninety-seven (23.0%) women had LTHD. Bisserial Spear-

men correlations between LTHD and SCS total score were

significant, negative and moderate (

r

= –0.31). SCS subscales,

except Common Humanity, showed significant correlations:

Self-Kindness/SK (

r

= –0.130), self-judgement (SJ) (0.313), iso-

lation (0.357), mindfulness (

r

= –0.102), over-identification (OI)

(

r

= 0.393). Independent sample

t

tests revealed that women with

vs. without LTHD had significantly lower levels of total SCS, SK and

Mindfulness scores and higher levels of SJ, Isolation and OI.Logistic

regression (assumptions were fulfilled, Tabachnick and Fidell,

2007) showed that the SCS explained 26.7%–43.6% of the LTHD vari-

ance and correctly classified 86.9%; the odds ratio (OR) was.865

(95% CI 0.834–0.898;

P

< 0.001). The model composed by the cor-

related dimensions explained 15.9%–24.0% and correctly classified

80.6%. Odds ratios: SK = 0.017; SJ = 0.021; isolation = 16.027; mind-

fulness = 0.167 and OI = 20.178 (all

P

< 0.05).

Conclusions

Self-compassion, specifically the ability to treat one-

self with care and understanding and to be aware and accepting

one’s present-moment experiences, decrease the probability of

having LTHD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1505

EV521

Interictal depressive disorders in

epilepsy patients

A. Matos Pires

, Y. Martins , M. Suarez Gomez

Local Health Unit of Baixo Alentejo, Department of Psychiatry and

Mental Health, Beja, Portugal

Corresponding author.

Introduction

Depression is recognized as more frequent psychi-

atric disorder in epilepsy patients with significant impact on their

health-related quality of life.