Table of Contents Table of Contents
Previous Page  517 / 812 Next Page
Information
Show Menu
Previous Page 517 / 812 Next Page
Page Background

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S513

of non-availability of trained health professionals and in attain-

ment of millennium development goals of reducing mother and

child mortality.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1496

EV512

Pros and cons of prescribing

potentially addictive medications for

patients with refractory depression

and anxiety

D. Kolar

Queen’s University, Kingston, Canada

Treatment resistant depression and refractory anxiety disorders are

major mental health problems associated with a poor quality of

life and a risk of suicide. These conditions require intensive biolog-

ical treatments combined with psychosocial interventions. There

are new treatments that are effective, particularly in the short run,

but they are associated with negative effects such as risk of addic-

tion. Ketamine produces fast improvement in treatment resistant

depression (TRD), but effects are short-lasting and there is no sus-

tained benefit. Oral formulations of ketamine are associated with a

risk of addiction. No one has idea how long time oral or intranasal

ketamine should be used.

Stimulant augmentation may cause a significant reduction in some

type of residual symptoms of depression but these improvements

will disappear almost immediately after discontinuing stimulant

medication. There is no consensus if a long-term use of stimulant

medication, such as in ADHD, is acceptable in patients with treat-

ment resistant depression. Treatment refractory anxiety disorders

may not respond to SSRI/SNRIs as expected. Although a long-term

use of benzodiazepines is not recommended, benzodiazepine aug-

mentation is currently again supported. However, treatment effects

usually disappear upon discontinuing BZDs. There is a common

practice of using synthetic cannabinoid, nabilone for nightmares

in PTSD. Long-term use of nabilone is unfortunately not uncom-

mon. Some patients may even prefer a medical marijuana to get

short improvements in their anxiety symptoms and depression.

Physicians should be very cautious when prescribe medications

with addictive potential particularly if there is no strong scientific

evidence of their efficacy.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1497

EV513

Does the supplementation of vitamin

D affect depressive symptoms?

P. Kolarov

, M. Stoimenova

Medical University – Pleven – Bulgaria, Department of Psychiatry

and Medical Psychology, Pleven, Bulgaria

Corresponding author.

Introduction

Depression has been linked to decreased levels of

vitamin D in adults and the altered dietary intake of calcium and

vitamin D has been reported to have implications for the devel-

opment of depressive symptoms. Although, the relation between

vitamin D and depression has been established, it is not yet clear

whether the supplementation of vitamin D could affect the clinical

manifestation of depression. Therefore, the aim of this study was to

determine whether the supplementation of vitamin D could affect

the development/course of depression.

Material and methods

A systematic literature search was per-

formed for randomized control trials (RCTs) in which vitamin D

was supplemented and depression was measured.

Results and discussion

Six studies were identified as being eligible

to be included in this review. The results regarding the supplemen-

tation of vitamin D and its effect on the course and manifestation

of depression were conflicting. One study concluded that the sup-

plementation of vitamin D3 had beneficial effect in depression and

another study reported no improvement in the indices of mental

well-being in the vitamin D supplemented group and rejected the

hypothesis that an annual high dose of vitamin D3 could prevent

depressive symptoms. The remainder four studies reported incon-

clusive results regarding vitaminD supplementation and the course

of depression.

Conclusion

As current literature displayed contradictory results

and no sound conclusion could be drawn regarding the supple-

mentation of vitamin D and its effect on depression, there is a need

of RCTs to determine whether the supplementation of vitamin D

levels could affect depression.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1498

EV514

The meaning of loss in the context of

elderly homes

C. Laranjeira

Piaget Institute, Research in Education and Community Intervention

RECI I&D, Viseu, Portugal

Introduction

Family plays a pivotal function in life of all human

being and their significance even increases with the age. However,

living in a elderly home may result in a multitude of losses which

must be addressed by individual through the process of grief.

Aim

The purpose of this study was to explore situations of loss

and grief among institutionalizes elders.

Methods

It is a qualitative, descriptive and exploratory research.

Data was collected from two Portuguese elderly homes in the

municipality of Viseu, Portugal. A purposeful sample of 7 elders was

recruited, and audiotaped face-to-face semi-structured interviews

were conducted.

Results

Three dimensions of emotional loss were created: loss

by death, loss by separation and other losses. Loss by separation

was further divided into three subcategories: marriage separation,

family separation and separation of peers living in the elderly home.

The death of a loved one reminds the elderly individual of his/her

own mortality, complicating the process of mourning. Separation,

however is much more difficult to overcome because there is a loss

among the living, with the possibility to lose the meaning of life

with the other one.

Conclusions

Understanding loss and grief among elderly people

is fundamental for nursing care, in order to help them with the

process of coping and to prevent institutionalization to become an

unpleasant experience. This will also offer health care facilities sug-

gested ways to reduce or combat loneliness and depression among

the elderly people.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1499

EV515

Prevalence and risk factors of

peripartum depressive symptoms

among South Korean women –

Preliminary data of a large

prospective study

S.Y. Lee

1 ,

, H.M. Ryu

2

1

Dankook University College of Medicine-Cheil General Hospital and

Women’s Healt, Psychiatry, Seoul, Republic of Korea