European Psychiatry - Volume 33 - March 2016

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S518 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
cancer women over a period of 12 months and their associations at
baseline, 6 and 12 months.
Methods It is a 12-months prospective cohort study. Two hun-
dred and twenty one female patients were included into the study.
Theywere assessed at the time of diagnosis, 6months and 12month
using Hospital Anxiety and Depression Scale (HADS), Quality-of-
Life Questionnaire (QLQ–C30), Version 3.0 and Multidimensional
Scale of Perceived Social Support (MSPSS). Relevant socio-clinical
characteristic information was collected.
Results The HADS anxiety and depression subscales scores of the
subjects were relatively low. The level of anxiety reduced signifi-
cantly at 6 and 12 months (baseline – 6 months, P = 0.002; baseline
– 12 months, P < 0.001). There were no changes in the level of
depression over the study period. The global status of QoL and
MSPSS scores were relatively high. There was positively correlation
between the global status of QoL and MSPSS for the study sub-
jects (Spearman’s rho = 0.31–0.36). Global status of QoL and MSPSS
scores were negatively correlated with anxiety and depression.
Conclusion Malaysian breast cancer women had relatively bet-
ter QoL with lower level of anxiety and depression. Perceived
social support was important associated factor for better QoL with
low level of psychological distress. It reflected the importance of
enhancing and maintaining the social support system for breast
cancer patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV528
Impact of pain and remission in the
functioning of patients with
depression in China
D. Novick ∗, Q. Shi , L. Yue , W. Montgomery , M.V. Moneta ,
S. Siddi . Haro
1 Eli Lilly and Company, Windlesham, Surrey, UK
2 Lilly Suzhou Pharmaceutica Company, Ltd., Shanghai, China
3 Eli Lilly Australia Pty Ltd, West Ryde, Australia
4 Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu,
CIBERSAM, Universitat de Barcelona, Barcelona, Spain
5 Section of Clinical Psychology, Department of Education,
Psychology, Philosophy, University of Cagliari, Italy
∗ Corresponding author.
Introduction Major depressive disorder (MDD) is the second
leading cause of disability in China.
Objective To analyze functioning during the course of treating
MDD in China, Taiwan and Hong Kong.
Aims To study the influence of pain and clinical remission on
functioning.
Methods This was a post-hoc analysis of a 6-month, prospec-
tive, observational study (n = 909) with 422 patients enrolled from
China ( n = 205; 48.6%), Taiwan (n = 199; 47.2%) and Hong Kong
(n = 18; 4.2%). Functioning was measured with the Sheehan Dis-
ability Scale (SDS), pain with the Somatic Symptom Inventory,
and severity of depression with the Quick Inventory of Depressive
Symptomatology-Self Report 16 (QIDS). Patients were classified as
having no pain, persistent pain (pain at any visit) or remitted pain
(pain only at baseline). Amixedmodel with repeatedmeasures was
fitted to analyze the relationship between pain and functioning.
Results At baseline, 40% of the patients had painful physical
symptoms. Patients with pain had a higher QIDS and lower SDS
(P < 0.05) at baseline. At 6months, patients with persistent pain had
lower functioning (P < 0.05). The regression model confirmed that
clinical remission was associated with higher functioning at end-
point and that patients with persistent pain had lower functioning
at endpoint when compared with the no pain group.
Conclusions Patients presenting with pain symptoms had lower
functioning at baseline. At 6 months, pain persistence was
associated with significantly lower functioning as measured by the
SDS. Clinical remission was associated with better functional out-
comes. The course of pain was related to the likelihood of achieving
remission.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV529
Prevalence of involuntary
hospitalization in patients with
depressive disorders
Á. Palma Conesa ∗, F.N. Dinamarca Cáceres ,
M. Grifell Guardia , L. Galingo Guarin ,
L. González Contreras , M.T. Campillo Sanz , V. Pérez Solà
1 Institut de Neuropsiquiatria i Addiccions-Parcde Salut Mar –
Barcelona – Spain, Psiquiatry, Barcelona, Spain
2 Institut Hospital del Mar d’Investigacions Mèdiques-IMIM-Parc de
Salut Mar-Barcelona-Spain, Psychiatry, Barcelona, Spain
∗ Corresponding author.
Introduction Depression is a disabling disorder with a high socio-
economic impact. It might require hospitalization for symptom
control and/or harm prevention. Other depressive disorders might
as well require hospitalization in benefit of the patient. Hos-
pitalization may be involuntary. Hospitalization willfulness in
depressive patients has not been systematically studied in recent
years.
Objective The aimof this study is to explore the necessity of invol-
untary hospitalization in patients presenting depressive symptoms
at the emergency service that were later diagnosed with a depres-
sive disorder.
Materials and methods From all patients visited in the psychi-
atric emergency service from 2012 to April 2015 those that were
hospitalized in the acute mental health unit and diagnosed with
a depressive disorder were studied. All those monopolar depres-
sion diagnoses were considered, excluding those within the bipolar
spectrum. Diagnosis followed CIE-9 criteria. A descriptive cross-
sectional study of the samples was then conducted. Statistical
analysis was performed using SPSS software (SPSS Inc., Chicago,
Ill.).
Results From all 385 depressive disorders, 169 were involuntary
admissions (43.9%), 196were voluntary (50.9%) and 20were sched-
uled (5.2%), difference was statistically significant ( P < 0.05). Mean
age, was 59.52 years for involuntary admissions, 61.7 for volun-
tary and 63.6 years for scheduled, with a statistically significant
difference (P < 0.05). Gender differences were not significant.
Conclusions Most depressive disorders were hospitalized vol-
untarily. However, a relevant percentage of patients required
involuntary hospitalization. Younger patients presented a higher
ratio of involuntary hospitalization. Reasons for involuntary hospi-
talization needs should be further studied.
Disclosure of interest The authors have not supplied their dec-
laration of competing interest. Liliana Galindo is a Rio Hortega
fellowship (ISC-III; CM14/00111).
EV530
Defense mechanism maturity and the
severity of depressive symptoms
M. Pandˇza ∗, M. Klari´c , S. Lovri´c , I. ˇColak , J. Mandari´c
1 University of Mostar, Department of Psychology, Mostar, Bosnia
and Herzegovina
2 University Hospital Mostar, Psychiatry Clinic, Mostar, Bosnia and
Herzegovina
∗ Corresponding author.