European Psychiatry - Volume 33 - March 2016

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S514 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
2 Dankook University College of Medicine-Cheil General Hospital and
Women’s Healt, Obstetrics and Gynecology, Seoul, Republic of Korea
∗ Corresponding author.
Objective The aim of this study was to assess period prevalence
and risk factors of peripartum depression in South Korean women.
Methods Two thousand four hundred and forty-nine women in
their first trimester of pregnancywere recruited, 1355womenwere
followed to the end of the study (1 month after delivery), 423
women are before the 1 month after delivery, 671 were dropped
out. There were four time points of assessment – 12, 24, 36 weeks
of gestation and 1 month after delivery. Depressive symptoms
were assessed using the validated Korean version of the Edinburgh
Postnatal Depression Scale. Risk factors were assessed across the
demographic features, past histories, obstetric histories, and psy-
chological status.
Results The prevalence of peripartum depressive symptoms
(above 10 points of K-EPDS) was found to be 18.8% at 1st trimester,
12.9% at 2nd trimester, 12.6% at 3rd trimester, and 15.7% at 1month
after delivery. Identified risk factors of depression at 1st trimester
were unmarried status, employed status, low family income, famil-
ial history and past history of depression, multigravida, unplanned
pregnancy, hyperemesis, and threatened abortion. In psychologi-
cal aspects, higher distress, lower marriage satisfaction, and lower
quality of life increased the risk of depression. The analyses to iden-
tify risk factors of postpartum depression will be performed after
the deliveries of recruited mothers are complete.
Conclusion A substantial proportion of mothers suffered from
peripartum depression from their early pregnancy in Seoul, Korea.
Intervention based on identified risk factors would be recom-
mended to help depressive pregnant mothers.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV516
Mindfulness, self-compassion and
spiritual well-being in chronic
depression
E. Silva , S. Simões , H. Espírito-Santo , M. Marques , L. Lemos ∗
Miguel TorgaInstitute, Psychology, Coimbra, Portugal
∗ Corresponding author.
Introduction Depression is one of the main causes of incapacity
worldwide. Research has shown that mindfulness practice, self-
compassion promotion, and spiritual well-being are beneficial for
depressed individuals.
Objective Analyze the associations between compassion, mind-
fulness, and spiritual well-being, during and after a therapeutic
intervention (concluded less than a year ago).
Aims To determine if mindfulness, self-compassion, and spiritual
well-being are predictors of depression.
Method Patients diagnosedwith chronic depressionwere treated
in a residential therapeutic community for a period of six to eight
months. The 63 participants (M= 32.84, SD = 10.24, range = 15–50
years old; 32 during treatment; 31 after treatment) were assessed
with the Beck Depression Inventory, the Questionnaire of the Five
Facets of Mindfulness, the Self-Compassion Scale, and the Spiritual
Well-Being Questionnaire.
Results There were differences in mindfulness, self-compassion,
spiritual well-being and depression by sex, existence of previous
psychiatric treatment, moment of the study (during versus after
intervention), and depression levels. After intervention the group
had higher levels of mindfulness and self-compassion (common
humanity) and lower levels of over-identification, compared with
group during treatment. The predictors of depressionwere the self-
judgment dimension of the self-compassion scale and, negatively,
themindfulness dimensions of non-reactivity andnon-judging, and
the spiritual well-being dimension of personal well-being.
Conclusion Results confirm the relationship between the study
variables and depression. This reinforces the importance of inter-
vention based on positive psychology enhancing positive areas
of human experience, rather than focusing on psychological pain,
weaknesses, and disabilities.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV517
Characteristic distributions of CBF
changes in remitted geriatric
depression
W. Liao ∗, Z. Wang , H. Shu , Z. Zhang
1 Neuropsychiatric Institute and Medical School of Southeast
University, Neurologic Department, Nanjing, China
2 Hangzhou Normal University, center for cognition and brain
disorders, Hangzhou, China
∗ Corresponding author.
Background The cerebral blood flow (CBF) is an absolute mea-
sure that superior to the relative measure of neural activity, blood
oxygenation-level-dependent (BOLD). The previous studies have
reported CBF abnormalities in the adult depressive patients. How-
ever, it is not clear whether the abnormal CBF could be improved
in the remitted geriatric depression (RGD).
Methods We enrolled 82 RGD patients and 90 age and educa-
tion matched healthy controls. All the subjects underwent 3-T
MRI with pseudo arterial spin labeling (pASL), and the pASL
data were analysis voxel-by-voxel with control the gray matter
volume.
Results Compared with the healthy controls, the RGD patients
demonstrated higher relative CBF value in left inferior tempo-
ral gyrus and left precuneus; while lower relative CBF value in
right medial temporal and occipital cortex, right insula operculum
(including parts of frontal, temporal and parietal cortex) and insula,
rightmedial frontal cortex.When comparedwith the remitted early
onset depression (EOD), the remitted late onset depression (LOD)
showed lowed relative CBF value in right angular gyrus.While there
was no significantly different relative CBF value between the RGD
patients accompanywithMCI and RGD patients with cognitive nor-
mal.
Conclusion The late life depression persists with CBF abnormali-
ties in the remitted state. And it is implicit that hyperperfusion in
the left brain cortex and hypoperfusion in the right brain cortex
could be the specific form to RGD patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV518
Civilization syndrome. New diagnosis
and new therapeutic approach
B. Łoza∗, M. Polikowska
Medical University of Warsaw, Psychiatry, Warsaw, Poland
∗ Corresponding author.
Introduction Although the relationship between the content of
stress and serious diseases, such as depression is not so obvi-
ous, underlying mechanisms encouraging more and more authors
to define a ‘civilization syndrome’ as a link between our modern
lifestyle, the civilization we live and psychosocial health problems.
With regard to the ‘civilization syndrome’, there are several new
candidates that have been spotted as the challenges for psychiatric
research, like burnout, infertility and solitude. All these phenom-
ena seem to increase epidemically and require urgent conceptual
and therapeutic studies.