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S514

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

2

Dankook University College of Medicine-Cheil General Hospital and

Women’s Healt, Obstetrics and Gynecology, Seoul, Republic of Korea

Corresponding author.

Objective

The aim of this study was to assess period prevalence

and risk factors of peripartum depression in South Korean women.

Methods

Two thousand four hundred and forty-nine women in

their first trimester of pregnancywere recruited, 1355womenwere

followed to the end of the study (1 month after delivery), 423

women are before the 1 month after delivery, 671 were dropped

out. There were four time points of assessment – 12, 24, 36 weeks

of gestation and 1 month after delivery. Depressive symptoms

were assessed using the validated Korean version of the Edinburgh

Postnatal Depression Scale. Risk factors were assessed across the

demographic features, past histories, obstetric histories, and psy-

chological status.

Results

The prevalence of peripartum depressive symptoms

(above 10 points of K-EPDS) was found to be 18.8% at 1st trimester,

12.9% at 2nd trimester, 12.6% at 3rd trimester, and 15.7% at 1month

after delivery. Identified risk factors of depression at 1st trimester

were unmarried status, employed status, low family income, famil-

ial history and past history of depression, multigravida, unplanned

pregnancy, hyperemesis, and threatened abortion. In psychologi-

cal aspects, higher distress, lower marriage satisfaction, and lower

quality of life increased the risk of depression. The analyses to iden-

tify risk factors of postpartum depression will be performed after

the deliveries of recruited mothers are complete.

Conclusion

A substantial proportion of mothers suffered from

peripartum depression from their early pregnancy in Seoul, Korea.

Intervention based on identified risk factors would be recom-

mended to help depressive pregnant mothers.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1500

EV516

Mindfulness, self-compassion and

spiritual well-being in chronic

depression

E. Silva , S. Simões , H. Espírito-Santo , M. Marques , L. Lemos

Miguel TorgaInstitute, Psychology, Coimbra, Portugal

Corresponding author.

Introduction

Depression is one of the main causes of incapacity

worldwide. Research has shown that mindfulness practice, self-

compassion promotion, and spiritual well-being are beneficial for

depressed individuals.

Objective

Analyze the associations between compassion, mind-

fulness, and spiritual well-being, during and after a therapeutic

intervention (concluded less than a year ago).

Aims

To determine if mindfulness, self-compassion, and spiritual

well-being are predictors of depression.

Method

Patients diagnosedwith chronic depressionwere treated

in a residential therapeutic community for a period of six to eight

months. The 63 participants (M= 32.84, SD = 10.24, range = 15–50

years old; 32 during treatment; 31 after treatment) were assessed

with the Beck Depression Inventory, the Questionnaire of the Five

Facets of Mindfulness, the Self-Compassion Scale, and the Spiritual

Well-Being Questionnaire.

Results

There were differences in mindfulness, self-compassion,

spiritual well-being and depression by sex, existence of previous

psychiatric treatment, moment of the study (during versus after

intervention), and depression levels. After intervention the group

had higher levels of mindfulness and self-compassion (common

humanity) and lower levels of over-identification, compared with

group during treatment. The predictors of depressionwere the self-

judgment dimension of the self-compassion scale and, negatively,

themindfulness dimensions of non-reactivity andnon-judging, and

the spiritual well-being dimension of personal well-being.

Conclusion

Results confirm the relationship between the study

variables and depression. This reinforces the importance of inter-

vention based on positive psychology enhancing positive areas

of human experience, rather than focusing on psychological pain,

weaknesses, and disabilities.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1501

EV517

Characteristic distributions of CBF

changes in remitted geriatric

depression

W. Liao

1 ,

, Z. Wang

2

, H. Shu

1

, Z. Zhang

1

1

Neuropsychiatric Institute and Medical School of Southeast

University, Neurologic Department, Nanjing, China

2

Hangzhou Normal University, center for cognition and brain

disorders, Hangzhou, China

Corresponding author.

Background

The cerebral blood flow (CBF) is an absolute mea-

sure that superior to the relative measure of neural activity, blood

oxygenation-level-dependent (BOLD). The previous studies have

reported CBF abnormalities in the adult depressive patients. How-

ever, it is not clear whether the abnormal CBF could be improved

in the remitted geriatric depression (RGD).

Methods

We enrolled 82 RGD patients and 90 age and educa-

tion matched healthy controls. All the subjects underwent 3-T

MRI with pseudo arterial spin labeling (pASL), and the pASL

data were analysis voxel-by-voxel with control the gray matter

volume.

Results

Compared with the healthy controls, the RGD patients

demonstrated higher relative CBF value in left inferior tempo-

ral gyrus and left precuneus; while lower relative CBF value in

right medial temporal and occipital cortex, right insula operculum

(including parts of frontal, temporal and parietal cortex) and insula,

rightmedial frontal cortex.When comparedwith the remitted early

onset depression (EOD), the remitted late onset depression (LOD)

showed lowed relative CBF value in right angular gyrus.While there

was no significantly different relative CBF value between the RGD

patients accompanywithMCI and RGD patients with cognitive nor-

mal.

Conclusion

The late life depression persists with CBF abnormali-

ties in the remitted state. And it is implicit that hyperperfusion in

the left brain cortex and hypoperfusion in the right brain cortex

could be the specific form to RGD patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1502

EV518

Civilization syndrome. New diagnosis

and new therapeutic approach

B. Łoza

, M. Polikowska

Medical University of Warsaw, Psychiatry, Warsaw, Poland

Corresponding author.

Introduction

Although the relationship between the content of

stress and serious diseases, such as depression is not so obvi-

ous, underlying mechanisms encouraging more and more authors

to define a ‘civilization syndrome’ as a link between our modern

lifestyle, the civilization we live and psychosocial health problems.

With regard to the ‘civilization syndrome’, there are several new

candidates that have been spotted as the challenges for psychiatric

research, like burnout, infertility and solitude. All these phenom-

ena seem to increase epidemically and require urgent conceptual

and therapeutic studies.