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S156

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

Study design

Initial evaluation of patients was carried out at the

first call, prior to the neurocognitive training. Follow-up study was

conducted one month after completion of training programs and

the final examination, after a year. In the comparison, group surveys

were conducted with the similar frequency.

Results

After training, the cognitive processes in schizophrenia

patientswere obtained by increasing the tempo of the performance,

improving concentration, improving the adequacy of long-term

thinking and memory have identified trend towards an increase

in operational short-term memory. According to the survey indi-

cated, with an increase in all indicators (the difference with the

control group ranged from 3 to 26%), the maximum improvement

falls on visual memory, and minimal attention to the function.

Conclusion

The neurocognitive training showed itself as an effec-

tive method of correcting neurocognitive deficits.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.235

EW118

Is empathy correlated to patients’

level of cognitive impairment in

schizophrenia?

R. Trabelsi

, A. Arous , J. Mrizak , H. Ben Ammar , A. Khalifa ,

Z. El Hechmi

Razi Hospital, Department Psychiatry F, Mannouba, Tunisia

Corresponding author.

Introduction

Empathy, which refers to the ability to understand

and share the thoughts and feelings of others, may be compromised

in schizophrenia (SCZ). Yet the relationship between empathy and

neurocognitive functioning remains unclear.

Objectives

To explore whether cognitive and affective empathy

are associated with the neurocognitive functioning in SCZ.

Methods

Fifty-eight outpatients with stable SCZ completed the

Questionnaire of Cognitive and Affective Empathy (QCAE) com-

prising five subscales intended to assess cognitive and affective

components of empathy. They also completed a neurocogni-

tive battery comprising the following tests: the Hopkins Verbal

Learning Test–Revised (HVLT-R), the Letter Digit Substitution Test

(LDST), the Stroop Test (ST), the “Double Barrage” of Zazzo (DBZ),

the Modified Card Sorting Test (MCST), Verbal Fluency (VF), the

Trail Making Test-Part A (TMT-A) and the Digit Span (DS).

Results

Better affective and cognitive empathy correlated with

better performance in the ST (less hesitations and less errors).

Patients with better cognitive empathy performed better in the

MCST (more categories achieved;

P

= 0.029) and in the LDST (more

substitutions per minute;

P

= 0.031).

Conclusions

Our results bolster support for the presence of an

association between NF and the decreased cognitive and affective

empathy in schizophrenia.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.236

EW119

Clinical symptomatology and empathy

in schizophrenia: Which relationship?

R. Trabelsi

, J. M

rizak , A. Arous , H. Ben Ammar , A. Khalifa ,

Z. El Hechmi

Razi Hospital, Department Psychiatry F, Mannouba, Tunisia

Corresponding author.

Introduction

The impairment of cognitive and affective empathy

among patients with schizophrenia (SCZ) may represent a signifi-

cant feature of the illness. However, the relationship between those

impairment and dimensions of psychosis remains unclear.

Objectives

To explore whether cognitive and affective empathy

are associated with severety of different psychotic symptoms.

Methods

Cognitive and affective empathy were evaluated in 58

patients with stable schizophrenia with the Questionnaire of Cog-

nitive and Affective Empathy (QCAE) comprising five subscales

intended to assess cognitive and affective components of empathy.

Symptomatology evaluation comprised the Positive and Nega-

tive Syndrome Scale (PANSS), the Calgary Depression Scale for

Schizophrenia (CDSS) and the Clinical Global Impressions Scale

Improvement and severity (CGI).

Results

Patients with better cognitive empathy had less total

CDSS scores (

P

= 0.036,

r

=

0.449) and lower CGI-severity scale

scores (

P

= 0.01,

r

=

0.536). Patients with better affective empa-

thy had lower scores (which means a better improvement) at the

CGI-improvement scale (

P

= 0.03,

r

=

0.461).

Conclusions

Our results suggest that empathy with its different

component is not totally independent of the clinical state of the

patient. Further studies are required to confirm whether empathy

deficits are state or trait aspects of SCZ.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.237

Comorbidity/Dual pathologies

EW120

Depressive symptoms in patients with

schizophrenia

T. Aladashvili

Tbilisi, Georgia

Introduction

Depression is common among patients with

schizophrenia and is associated with a wide range of poor out-

comes, including psychotic relapse and suicide. The aim of the

study is to evaluate the presence of depressive symptoms in

patients with schizophrenia and to compare depression intensity

in schizophrenic patients and patients with depressive disorder.

Methods

In this cross sectional study were included 40 patients

from both genders. Patients were divided in 2 groups: (1) exam-

ined group: 20 schizophrenic patients who presented depressive

symptomatology. Depressive symptoms-evaluated with the 17-

item Hamilton Rating Scale for Depression. Inclusion criteria:

schizophrenic disorder by ICD-10 (F20.0-F20.9), total score higher

than 7 on the HRSD-17 and age between 25 and 65; (2) control

group: 20 patients with depressive disorder. Inclusion criteria:

recurrent depressive disorder by ICD-10 (F33.0-F33.9), total score

higher than 7 on the HRSD-17 and age between 25 and 65.

Psychiatric rating scales for clinical evaluation of prominence of

symptomatology: 17-item Hamilton Rating Scale for Depression

(HRSD-17) and PANSS (Positive And Negative Syndrome Scale).

Results

The prevalence of patients with depressive symptoms

among the schizophrenic patients was 45% i.e. out of 20 evaluated

patients with schizophrenia, 9 showed depressive symptoms. The

total score in the remaining 11 patients on the HRSD-17 was lower

than 7 and they were excluded. Difference between the two groups

for gender difference was not statistically significant.

Conclusions

The percentage of patients with depressive symp-

toms among the patients with schizophrenic disorder was 45%.

Schizophrenic patients more frequently presented mild and mod-

erate depression in comparison to the control group. In themajority

of subjects with schizophrenia and depressive symptoms positive

schizophrenic symptomatology was predominant.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.238