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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

S151

Aims

To assess the clinical correlates of comorbid chronic tics/TS

in an inpatient preadolescent population.

Methods

A retrospective naturalistic study of all patients admit-

ted to our unit from 2009 to 2014 was conducted. Children with

and without chronic tics/TS were compared in terms of age, gen-

der, family history of mental illness, history of neurodevelopmental

problems in siblings, medication on admission and at discharge,

length of admission and functional outcomes using Chi

2

and

t

-tests

for categorical and continuous data respectively.

Results

A total of 133 children (mean age = 11.2 years) were

included. Twenty-five (18.8%) were diagnosed with chronic tics/TS.

Autism spectrum disorder was the most commonly comorbid

diagnosis (84%), with the second most common being an anxi-

ety disorder/OCD (52%). Statistically significant higher percentages

of learning disability, neurodevelopmental problems in siblings,

medication at discharge and longer inpatient admissions were

identified in children with tics compared with the rest of the sam-

ple. No other differences were found.

Conclusions

The prevalence of chronic tics/TS in children need-

ing inpatient treatment is significant. In our sample, chronic tics/TS

seem to represent a marker of increased neurodevelopmental

deviance and overall symptom severity.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.220

Classification

EW103

Diagnostic stability of acute and

transient psychotic disorder: A

systematic review and meta-analysis

Á. López Díaz

1 ,

, S. Galiano Rus

1

, A. Soler Iborte

2

,

J.I. Aznarte López

2

, J.L. Fernández González

1

1

Hospital San Juan de la Cruz, Mental Health Services, Úbeda, Spain

2

Hospital San Agustín, Mental Health Services, Linares, Spain

Corresponding author.

Introduction

The validity and diagnostic stability of acute and

transient psychotic disorder (ATPD) has been questioned by sev-

eral authors, since its introduction in the International Statistical

Classification of Diseases (ICD-10).

Objective

To determine the overall diagnostic stability of ATPD

in scientific literature.

Method

A systematic review and meta-analysis of prospective

studies and retrospective chart reviews. Computerized search was

performed in MEDLINE/PubMed, EMBASE, and Google Scholar,

using the terms: “acute and transient psychotic disorder”, or

“acute psychosis”, and “stability”, or “outcome”, or “long-term”, or

“follow-up”, or “course”. Search was restricted to works in English

published between 1993 and 2015, according to ICD-10 criteria.

Opinion articles, individual case reports, researches with less than

ten subjects, and overlapping studies were excluded. Data analy-

sis was conducted using MedCalc software, version 15.8. Statistical

procedure was calculated for meta-analysis of proportions.

Results

Twenty-six studies met the inclusion criteria (

n

= 10852).

For methodological purposes, a distinction was made between

short-term (less than 2 years), medium-term (between 2–7 years),

and long-term stability (more than 7 years). For short-term group

(

k

= 5), the overall stability was 60.69% (fixed effects model);

Cochran’s heterogeneity statistic

Q

= 14.9,

I

2

= 73.15%,

P

= 0.0049.

For medium-term group (

k

= 15), it was 49.99%;

Q

= 181.6,

I

2

= 92.29%,

P

< 0.0001. For long-term group (

k

= 6), it was 61.86%;

Q

= 35.12,

I

2

= 92.29%,

P

< 0.0001.

Conclusion

The global stability of ATPD indicates at the validity

of the construct, but should be redefined in future revisions of ICD,

to clarify better diagnostic criteria, and more predictive power.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.221

Cognitive neuroscience

EW104

Human factors in driving accidents: A

cognitive investigation in the Gulf

context

Y. Alotaibi

Qatar University, Social Sciences, Doha, Qatar

Introduction

Human factors have been reported as the reason

behind the majority of car accidents. However, to date, no stud-

ies at least in the Arab world generally and Gulf area specifically,

conducted a comprehensive examination of cognitive functioning

as potential predictors of car accidents and driving violations.

Objectives

Examining the role of cognitive functions e.g., verbal

working memory, attentional control as predictors of traffic acci-

dents and driving violations.

Aims

Examining the predictability of individual’s cognition of

occurrence of driving violations and accidents.

Methods

The studywas carried on a sample of hundred and thirty

two participants whose age ranged between 24 and 31 years. They

were classified into groups of violators and non-violators, acci-

dent free and accident involved as well. Cognitive functioning were

measured using self-reports and task performance, and a series of

ANOVAS as well as stepwise multiple regressions were conducted

to test the research hypothesis.

Results

Findings showed significant differences between viola-

tors and non-violators and between the accident free and accident

involved groups in almost all of the considered factors, except for

the decision making factor. Moreover, Pearson product-moment

correlations showed that there were significant negative correla-

tions between age, driving violations, and cognitive performance

and the accidents.

Conclusions

Human cognition such as executive functioning and

mental planning are key factors for predicting driving behavior and

traffic accidents. The study results have many implications in diag-

nosing and preventing or at least reducing driving violations and

road accidents.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.222

EW105

Effects of negative autobiographical

memories retrieval on corticospinal

excitability and sensorimotor

integration

L. Mineo

1 , C. C

oncerto

2 , D.

Patel

3 , T. M

yorga

3 , D.

Coira

4 ,

E. Chusid

3 , E. A

guglia

2 , F. B

attaglia

1 ,

1

Seton Hall University, Health and medical sciences, South Orange,

USA

2

Clinical and experimental medicine, Psychiatry Unit, Catania, Italy

3

New York College of Podiatric Medicine, Preclinical Sciences, NY,

USA