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S154

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

In the streamof flurry of publications grappling different paradigms

to tackle underlyingmechanisms of moral decision-making, EVENT

RELATED POTENtial (ERP) studies is beginning to explore psy-

chophysiological components in the moral domain, focused on

observing various moral behaviors in the experimental situations.

This research was aimed at providing a newmethod of study inves-

tigating neural correlates of subjective moral decision-making in

which we hypothesize that the social congruent or in-congruent

context, could emerge a salience brain response in intuitive or

cognitive control related responses toward moral dilemmas. Elec-

trophysiological data were recorded from the scalp a 32-channel

recording system complying with the international 10–20 system.

The average N2 (175–300ms) and LPP (300–600ms) amplitude

and latency were measured after the onset of putative counter-

part response. Repeated measure ANOVA revealed that there was a

difference between congruent versus in-congruent social response

to high conflict scenarios in LPP amplitude in right lateral and

frontal electrodes

F

(4, 174)

= 5.812,

P

< 0.001 (Fig. 1). The findings

also, suggest that N2 latency in less conflict moral scenarios may

appear earlier compared with high conflict moral scenarios dur-

ing in congruent social response in frontal electrodes especially

left area

F

(3, 174)

= 3.013,

P

< 0.05 (Fig. 2, figures are not available for

this abstract). In conclusion, these results were either extend pre-

vious neurophysiological findings on classic moral scenarios and

consistent with the notion that right hemisphere would be much

more representative of cognitive control process during high con-

flict moral decision-making, while left frontal electrodes engaged

in early intuitive process.

Keywords

Moral decision-making; Cognitive control; Intuition;

Social context; Late positive potential; N2

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.229

EW112

Depressive pseudodementia in Greek

patients: How differential diagnosis

can lead to early diagnosis

G. Lyrakos

1 ,

, N. Tsioumas

2

, V. Spinaris

1

, E. Margioti

3

, P. Sakka

3

,

I. Spyropoulos

1

1

General Hospital Nikaia “Ag. Panteleimon”, Psychiatric, Nikaia,

Greece

2

City Unity College-Cardiff MET, MSc Health Psychology, Athens,

Greece

3

Day Center of Alzheimer’s Disease, Day center, Athens, Greece

Corresponding author.

Background

The term Pseudodementia, as presented by Kiloh, is

being used to describe the clinical image characterized by depres-

sion combinedwith impairment in cognitive functionswhich reacts

positively in treatment with antidepressants.

Aim

To explore the aspects that make this condition unique, so

that mental health professional will be able to use the proper psy-

chometric tools when they face patients with confusing symptoms.

Method

Hundred and thirty-one participants were recruited

from the B’ Psychiatric Clinic of G.H.N.P “Agios Panteleimon” and

Day Center of Alzheimer’s Disease in Amarousion, with 56 (42.7%)

males and 75 (57.3%) females. All participants were administered

the MoCA and the DASS21 questionnaires. Statistical analysis was

performed with SPSS21.

Results

The findings reported a significant difference in the scores

of MoCA done by patients with dementia (M= 13.9, SD = 5.4) and

patients with depression (M= 20.5, SD = 4.9) while both groups

scored below the accepted scores indicating cognitive impair-

ment [CI]. However, analysis showed that in the following sectors

of MoCA, depressive patients scored significantly higher than

demented ones: visuospatial (MD = 0.651), clock (MD = 1.288), ori-

entation (MD = 1.212) and delayed recall (MD = 1.329).

Conclusion

Findings shows a significant pattern in the difference

between depressed and patients with cognitive impairment. These

findings suggest that mental health professionals should use neu-

ropsychological measurements like MoCA when evaluating such

cases in order to be able to diagnose effectively cases of pseudode-

mentia.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.230

EW113

Hemispheric processing of idioms in

schizophrenia and autism spectrum

disorder

N. Mashal

1 ,

, R. Saban-Bezalel

1

, S. Hess

2

, D. Dolfin

2

,

H. Hermesh

2

1

Bar Ilan university, Education, Ramat gan, Israel

2

Geha Mental Health, Geha Mental Health, Petah Tikva, Israel

Corresponding author.

Introduction

Schizophrenia (SZ) and autism (ASD) have been his-

torically considered as a related diagnostic category. Studies point

to difficulties in comprehension of figurative language and a ten-

dency to interpret it in a literal manner in both populations.

Aims

To examine idiom comprehension and pattern of hemi-

spheric processing of idioms in SZ as compared to ASD.

Methods

Nineteen adults diagnosedwith SZ, 24 adults diagnosed

with ASD, and 22 typically developing (TD) adults participated in

the study. The SZ and the ASD groups were matched by gender and

verbal abilities. Participants performed a lexical decision task to

either literally or idiomatically related target words presented to

either the left or the right visual field using the divided visual field

paradigm.

Results

First, although both SZ and ASD groups performed worse

than TD, they demonstrated relatively unimpaired comprehension

of idiomatic expressions. No significant difference in idiom com-

prehension was found between the SZ and the ASD groups. Second,

adults with SZ demonstrated a similar pattern of hemispheric lat-

eralization (i.e. right lateralization) as TD participants during the

processing of the literal interpretations of idioms. In contrast to

SZ and TD participants, ASD participants demonstrated a bilateral

pattern of hemispheric processing.

Conclusions

Our findings suggest that brain lateralization is

intact in adults with SZ but atypical in adults with ASD. The atyp-

ical hemispheric processing in addition to relatively unimpaired

understanding of figurative language can point to a compensation

mechanism in ASD. Thus, the current findings point to a different

brain mechanism in each clinical group.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.231

EW114

Do patients with better

neuro-cognition have better theory of

mind?

J. Mrizak

, A. A

rous , R. Trabelsi , A. Aissa , H. Ben Ammar ,

Z. El Hechmi

Razi Hospital, Psychiatry F, Mannouba, Tunisia

Corresponding author.

Introduction

Theory of mind (ToM) has repeatedly been shown

to be compromised in many patients with schizophrenia (SCZ). By

contrast, the association between ToMdeficits and neuro-cognitive

functioning (NF) remains uncertain.

Objectives

To investigate the association between ToM function-

ing and neuro-cognitive functioning in SCZ.