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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S72–S115

S81

32.7% were male (

P

< 0.001). The multivariate logistic regression

model showed that female sex is a very strong predictor for the

development of depression during the interferon treatment [Exp

(B) = 6.729]. There were no significant sex differences in the preva-

lence of depression in the control group.

Conclusions

Our study (the longest study in this area) indicate

that the prevalence of depression is significantly higher in female

subjects with CHC during antiviral treatment.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.027

FC24

Depression as an interdisciplinary

problem

A. Vasileva

1 ,

, N. Neznanov (Director)

2

1

Bekhterev Psychoneurological Institute, Medical Faculty of St.

Petersburg University, neurosis and psychotherapy, Saint-Petersburg,

Russia

2

Bekhterev Psychoneurological Institute, Medical Faculty of St.

Petersburg University, Saint-Petersburg, Russia

Corresponding author.

Traditionally depression was defined as a mental illness. Acknowl-

edgment of biopsychosocial model in modern medicine brought

about a number of interdisciplinary studies. In the meantime, a

number of correlations in the onset, cause and prognosis between

depression and other somatic as well as mental illnesses were

discovered. The research results showed that from one hand,

depression could be an independent factor of the possible develop-

ment of heart infarct, on the other hand it can influence the recovery

process in cardiological patients. The conducted studies established

some commonpathways indepression and vascular diseases devel-

opment. Psychoneuroimmunological research gives the data about

the influence of anxiety and depression on the interleukine pro-

file that could be a matter of further investigation of the possible

links between depression and cancer diseases. The other dimension

is the addiction impact on depression onset. The interrelationship

between epilepsy as organic brain disease and depression is also

worth of attentional. Hypercortisolemia and low-grade inflamma-

tion plays an important role both in depression and dementia.

There is also a strong correlation between personality traits and

depression itself and as response to unfavorable circumstances and

somatic illness as well. We propose to apply to depression the

principles of pathological stable circuits with the self-sustained

reverbation engram chains mechanisms. All these data calls for

consideration of depression as an interdisciplinary phenomena.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.028

Eating disorders

FC25

Clinical features in insulin-treated

diabetes with comorbid diabulimia,

disordered eating behaviors and

eating disorders

V. Deiana

1 ,

, E. Diana

1

, F. Pinna

1

, M.G. Atzeni

1

, F. Medda

1

,

D. Manca

1

, E. Mascia

1

, F. Farci

2

, M. Ghiani

2

, R. Cau

2

, M. Tuveri

3

,

E. Cossu

3

, L. Elena

3

, S. Mariotti

3

, B. Carpiniello

1

1

University of Cagliari, Clinica Psichiatrica, Cagliari, Italy

2

ASL Cagliari, Unità Operativa di Diabetologia, Quartu Sant’Elena,

Italy

3

AOU Cagliari, Unità Operativa di Diabetologia, Monserrato, Italy

Corresponding author.

Adherence to self-management and medication regimens is

required to achieve blood glucose control in diabetic patients.

Therefore, diabulimia, the deliberate insulin restriction/omission to

lose weight, and other disordered eating behaviors (DEBs) or eating

disorders (EDs), place these patients at risk of complications.

We aimed to establish the frequency of diabulimia, DEBs and EDs

among patients with type 1 and 2 diabetes (T1DM and T2DM) and

their association with other clinical features.

A total of 211 insulin-treated diabetic patients (13–55 years old)

answered the Diabetes Eating Problem Survey-Revised (DEPS-R), a

diabetes-specific screening tool for DEBs, and the Eating Disorders

Inventory-3 (EDI-3). SCID-I modified according to DSM-5 criteria

was used to diagnose EDs.

At the DEPS-R, 20.8% of the sample scored above the cutoff, more

frequently females (

P

= 0.005), patients with T1DM (

P

= 0.045), with

a diagnosis of ED (

P

< 0.001), positive to the EDI-3 (

P

0.001),

with physical comorbidities (

P

= 0.003), withHbA1c > 7% (

P

= 0.020).

Combining data from the interview with the results at the DEPS-

R, 60.2% of the sample presented diabulimia. Dividing the sample

by gender, we found that diabulimic females more frequently used

diet pills (

P

= 0.006), had significantly higher HbA1c (

P

= 0.019) and

STAI-Y1 scores (

P

= 0.004). Other DEBs comprised dietary restraint

(51.8% of the sample), binge eating (42.2%), vomiting (6.2%), diet

pills (7.1%) or laxatives (1.9%) or diuretics use (4.3%). Overall, 21.8%

of the sample, mostly females (

P

< 0.001) met criteria for at least

one DSM-5 diagnosis of ED.

Diabetic patients, especiallywomen, should be carefullymonitored

for the presence of diabulimia, BEDs and EDs.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.029

FC26

Gender and age differences in eating

and drinking risk behaviors in Italian

high school students

V. Deiana

, L. Sanna , P. Milia , F. Pinna , L. Puddu , F. Fatteri ,

S. Lostia di Santa Sofia , A. Ghiani , A. Lai , F. Medda , M.G. Atzeni ,

D. Manca , C. Arzedi , B. Carpiniello

University of Cagliari, Clinica Psichiatrica, Cagliari, Italy

Corresponding author.

Drunkorexia, limiting food intake before alcohol consumption,

increases teenagers and young adults’ risk for negative alcohol-

related health consequences.

The purpose of the present study is to explore gender and age

differences regarding weight management behaviors and alcohol

consumption among 3004 students aged 13 to 24 years.

The following questionnaires were administered: Eating Disor-

der Inventory-3 (EDI-3), Alcohol Use Disorders Identification Test

(AUDIT) and Compensatory Eating and Behaviors in Response to

Alcohol Consumption Scale (CEBRACS).

EDI-3 showed that 11.3% of the sample met the threshold on the

“Drive for Thinness” (DT) scale, 28.9% on the “Bulimia” (B) scale,

17.2% on the “Body Dissatisfaction” (BD) scale. Females presented

a higher risk at DT, B andBD scales (

P

< 0.001), and the risk of bulimia

was higher in those aged

16 years (

P

= 0.028). AUDIT revealed a

greater clinical risk of alcohol-related problems inmales (

P

< 0.001)

and in those aged > 16 years (

P

< 0.001). Drunkorexia was found

in 44% of the sample, without significant difference in relation to

gender and age.

Girls and younger students have more weight concerns, while boys

and older students are at greater risk of alcohol use disorders.

Therefore, no specific group should be considered risk-free with

respect to drunkorexia.