European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S72–S115 S81
32.7% were male (P < 0.001). The multivariate logistic regression
model showed that female sex is a very strong predictor for the
development of depression during the interferon treatment [Exp
(B) = 6.729]. There were no significant sex differences in the preva-
lence of depression in the control group.
Conclusions Our study (the longest study in this area) indicate
that the prevalence of depression is significantly higher in female
subjects with CHC during antiviral treatment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
FC24
Depression as an interdisciplinary
problem
A. Vasileva ∗, N. Neznanov (Director)
1 Bekhterev Psychoneurological Institute, Medical Faculty of St.
Petersburg University, neurosis and psychotherapy, Saint-Petersburg,
Russia
2 Bekhterev Psychoneurological Institute, Medical Faculty of St.
Petersburg University, Saint-Petersburg, Russia
∗ Corresponding author.
Traditionally depression was defined as a mental illness. Acknowl-
edgment of biopsychosocial model in modern medicine brought
about a number of interdisciplinary studies. In the meantime, a
number of correlations in the onset, cause and prognosis between
depression and other somatic as well as mental illnesses were
discovered. The research results showed that from one hand,
depression could be an independent factor of the possible develop-
ment of heart infarct, on the other hand it can influence the recovery
process in cardiological patients. The conducted studies established
some commonpathways indepression and vascular diseases devel-
opment. Psychoneuroimmunological research gives the data about
the influence of anxiety and depression on the interleukine pro-
file that could be a matter of further investigation of the possible
links between depression and cancer diseases. The other dimension
is the addiction impact on depression onset. The interrelationship
between epilepsy as organic brain disease and depression is also
worth of attentional. Hypercortisolemia and low-grade inflamma-
tion plays an important role both in depression and dementia.
There is also a strong correlation between personality traits and
depression itself and as response to unfavorable circumstances and
somatic illness as well. We propose to apply to depression the
principles of pathological stable circuits with the self-sustained
reverbation engram chains mechanisms. All these data calls for
consideration of depression as an interdisciplinary phenomena.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Eating disorders
FC25
Clinical features in insulin-treated
diabetes with comorbid diabulimia,
disordered eating behaviors and
eating disorders
V. Deiana ∗, E. Diana , F. Pinna , M.G. Atzeni , F. Medda ,
D. Manca , E. Mascia , F. Farci , M. Ghiani , R. Cau , M. Tuveri ,
E. Cossu , L. Elena , S. Mariotti , B. Carpiniello
1 University of Cagliari, Clinica Psichiatrica, Cagliari, Italy
2 ASL Cagliari, Unità Operativa di Diabetologia, Quartu Sant’Elena,
Italy
3 AOU Cagliari, Unità Operativa di Diabetologia, Monserrato, Italy
∗ Corresponding author.
Adherence to self-management and medication regimens is
required to achieve blood glucose control in diabetic patients.
Therefore, diabulimia, the deliberate insulin restriction/omission to
lose weight, and other disordered eating behaviors (DEBs) or eating
disorders (EDs), place these patients at risk of complications.
We aimed to establish the frequency of diabulimia, DEBs and EDs
among patients with type 1 and 2 diabetes (T1DM and T2DM) and
their association with other clinical features.
A total of 211 insulin-treated diabetic patients (13–55 years old)
answered the Diabetes Eating Problem Survey-Revised (DEPS-R), a
diabetes-specific screening tool for DEBs, and the Eating Disorders
Inventory-3 (EDI-3). SCID-I modified according to DSM-5 criteria
was used to diagnose EDs.
At the DEPS-R, 20.8% of the sample scored above the cutoff, more
frequently females (P = 0.005), patients with T1DM (P = 0.045), with
a diagnosis of ED (P < 0.001), positive to the EDI-3 (P ≤ 0.001),
with physical comorbidities (P= 0.003), withHbA1c > 7% ( P= 0.020).
Combining data from the interview with the results at the DEPS-
R, 60.2% of the sample presented diabulimia. Dividing the sample
by gender, we found that diabulimic females more frequently used
diet pills (P = 0.006), had significantly higher HbA1c (P = 0.019) and
STAI-Y1 scores (P = 0.004). Other DEBs comprised dietary restraint
(51.8% of the sample), binge eating (42.2%), vomiting (6.2%), diet
pills (7.1%) or laxatives (1.9%) or diuretics use (4.3%). Overall, 21.8%
of the sample, mostly females (P < 0.001) met criteria for at least
one DSM-5 diagnosis of ED.
Diabetic patients, especiallywomen, should be carefullymonitored
for the presence of diabulimia, BEDs and EDs.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
FC26
Gender and age differences in eating
and drinking risk behaviors in Italian
high school students
V. Deiana ∗, L. Sanna , P. Milia , F. Pinna , L. Puddu , F. Fatteri ,
S. Lostia di Santa Sofia , A. Ghiani , A. Lai , F. Medda , M.G. Atzeni ,
D. Manca , C. Arzedi , B. Carpiniello
University of Cagliari, Clinica Psichiatrica, Cagliari, Italy
∗ Corresponding author.
Drunkorexia, limiting food intake before alcohol consumption,
increases teenagers and young adults’ risk for negative alcohol-
related health consequences.
The purpose of the present study is to explore gender and age
differences regarding weight management behaviors and alcohol
consumption among 3004 students aged 13 to 24 years.
The following questionnaires were administered: Eating Disor-
der Inventory-3 (EDI-3), Alcohol Use Disorders Identification Test
(AUDIT) and Compensatory Eating and Behaviors in Response to
Alcohol Consumption Scale (CEBRACS).
EDI-3 showed that 11.3% of the sample met the threshold on the
“Drive for Thinness” (DT) scale, 28.9% on the “Bulimia” (B) scale,
17.2% on the “Body Dissatisfaction” (BD) scale. Females presented
a higher risk at DT, B andBD scales (P < 0.001), and the risk of bulimia
was higher in those aged≤ 16 years (P = 0.028). AUDIT revealed a
greater clinical risk of alcohol-related problems inmales (P < 0.001)
and in those aged > 16 years (P < 0.001). Drunkorexia was found
in 44% of the sample, without significant difference in relation to
gender and age.
Girls and younger students have more weight concerns, while boys
and older students are at greater risk of alcohol use disorders.
Therefore, no specific group should be considered risk-free with
respect to drunkorexia.