European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry
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Addictive behaviours
EV01
Efficacy of nalmefene in a sample of
patients with alcohol dependence
J.A. Aguado Ma˜nas ∗, O. Segurado
1 Centro Hospitalario Benito Menni, Psychiatry, Valladolid, Spain
2 Hospital Universitario Rio Hortega, Psychiatry, Valladolid, Spain
∗ Corresponding author.
Introduction It is well known the high rate of alcohol abuse and
dependence in Spain. Specifically, in Castilla and Léon as a wine
region, the risk of developing alcoholism is 1 of 10 men and 1 of 15
women [1].
Objective The aim of the study is to assess the efficacy of nalme-
fene in reducing alcohol consumption and its complications, in a
sample of patients with alcoholism.
Materials and methods It is an open, naturalistic, observational
and descriptive study in a sample of 18 patientswith alcohol depen-
dence diagnosis.
We collected standard demographic variables, but also living alone,
social support and work.
In addition, clinical variables as SD (standard drinks) per day, time
of illness, concomitant diseases, number of admissions, periods of
abstinence, abstinence longer duration, nalmefene doses and other
treatments were collected. These variables were reassessed at first,
3th and 6th month.
Results In our sample the average profile is a man (75%) with an
age of 46, who lives alone (68%), in urban area and with poor social
support.
Average SD consumed at the beginning was 53, one month later
was 26, after three months was 14 and 6 months later was 5, with a
total abstinence rate of 65% at the end of the period. Logically there
was also a dramatic reduction in somatic and social complications.
Conclusions Nalmefene is demonstrated as a useful drug in
reducing alcohol consumption and its complications.
Nalmefene also proves to be effective for achieving complete alco-
hol abstinence starting with a reduction plan.
Reference not available.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV02
Prevalence rate, demographic and
clinical predictors of substance use
disorders in emergency room
psychiatric patients of a tertiary
hospital in Canada
V. Agyapong ∗, M. Juhas
1 Department of Psychiaty, Fort McMurray, University of Alberta,
Canada
2 Department of Psychiatry, Edmonton, University of Alberta, Canada
∗ Corresponding author.
Background There is only a limited body of literature which has
examined the factors which can predict the presence of substance
use disorders (SUD) in psychiatric patients seeking emergency
room (ER) treatment.
Objective To examine the factors that can predict the likelihood
that a patient presenting to the emergency room and referred to
the liaison psychiatric team will suffer from a SUD.
Methods Nineteen independent demographic and clinical factors
from data assessment tools for 477 patients assessed by the liai-
son psychiatric team in the ER over 12 months were compiled and
analysed using univariate analyses and logistic regression in SPSS
(version 20).
Results The 12-month prevalence rate of all SUDs in our clinical
sample was 24.7%. Patients who presented to the ER with a chief
alcohol and/or drug related complaint (withdrawal or intoxica-
tion) were 142 times more likely to fulfill the diagnostic criteria for
SUD compared to those who presented with non-SUD related com-
plaints. Male patients or patients with forensic history were both
three times more likely to suffer from SUD than female patients or
patients with no forensic history, respectively.
Conclusion There is a high prevalence of SUDs among psychiatric
patients assessed in the ER. In addition to targeting patients who
present to the ER with an alcohol or drug withdrawal/intoxication
for brief psycho-educational interventions and referrals to addic-
tion treatment services, patients with forensic history and male
patients should be targeted for SUD screening.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
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