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Page Background European Psychiatry 33S (2016) S349–S805

Available online at

ScienceDirect

www.sciencedirect.com

24th European Congress of Psychiatry

e-Poster viewing

Addictive behaviours

EV01

Efficacy of nalmefene in a sample of

patients with alcohol dependence

J.A. Aguado Ma˜nas

1 ,

, O. Segurado

2

1

Centro Hospitalario Benito Menni, Psychiatry, Valladolid, Spain

2

Hospital Universitario Rio Hortega, Psychiatry, Valladolid, Spain

Corresponding author.

Introduction

It is well known the high rate of alcohol abuse and

dependence in Spain. Specifically, in Castilla and Léon as a wine

region, the risk of developing alcoholism is 1 of 10 men and 1 of 15

women [1].

Objective

The aim of the study is to assess the efficacy of nalme-

fene in reducing alcohol consumption and its complications, in a

sample of patients with alcoholism.

Materials and methods

It is an open, naturalistic, observational

and descriptive study in a sample of 18 patientswith alcohol depen-

dence diagnosis.

We collected standard demographic variables, but also living alone,

social support and work.

In addition, clinical variables as SD (standard drinks) per day, time

of illness, concomitant diseases, number of admissions, periods of

abstinence, abstinence longer duration, nalmefene doses and other

treatments were collected. These variables were reassessed at first,

3th and 6th month.

Results

In our sample the average profile is a man (75%) with an

age of 46, who lives alone (68%), in urban area and with poor social

support.

Average SD consumed at the beginning was 53, one month later

was 26, after three months was 14 and 6 months later was 5, with a

total abstinence rate of 65% at the end of the period. Logically there

was also a dramatic reduction in somatic and social complications.

Conclusions

Nalmefene is demonstrated as a useful drug in

reducing alcohol consumption and its complications.

Nalmefene also proves to be effective for achieving complete alco-

hol abstinence starting with a reduction plan.

Reference not available.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.986

EV02

Prevalence rate, demographic and

clinical predictors of substance use

disorders in emergency room

psychiatric patients of a tertiary

hospital in Canada

V. Agyapong

1 ,

, M. Juhas

2

1

Department of Psychiaty, Fort McMurray, University of Alberta,

Canada

2

Department of Psychiatry, Edmonton, University of Alberta, Canada

Corresponding author.

Background

There is only a limited body of literature which has

examined the factors which can predict the presence of substance

use disorders (SUD) in psychiatric patients seeking emergency

room (ER) treatment.

Objective

To examine the factors that can predict the likelihood

that a patient presenting to the emergency room and referred to

the liaison psychiatric team will suffer from a SUD.

Methods

Nineteen independent demographic and clinical factors

from data assessment tools for 477 patients assessed by the liai-

son psychiatric team in the ER over 12 months were compiled and

analysed using univariate analyses and logistic regression in SPSS

(version 20).

Results

The 12-month prevalence rate of all SUDs in our clinical

sample was 24.7%. Patients who presented to the ER with a chief

alcohol and/or drug related complaint (withdrawal or intoxica-

tion) were 142 times more likely to fulfill the diagnostic criteria for

SUD compared to those who presented with non-SUD related com-

plaints. Male patients or patients with forensic history were both

three times more likely to suffer from SUD than female patients or

patients with no forensic history, respectively.

Conclusion

There is a high prevalence of SUDs among psychiatric

patients assessed in the ER. In addition to targeting patients who

present to the ER with an alcohol or drug withdrawal/intoxication

for brief psycho-educational interventions and referrals to addic-

tion treatment services, patients with forensic history and male

patients should be targeted for SUD screening.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.987

0924-9338/$ – see front matter