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S346

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

scoring system for use in phase 2/3 clinical trials with DS popula-

tions.

Methods

Impairment in functional and adaptive behaviors in

DS – “speech”, “activities of daily living”, “social function-

ing” and “non-compliance” – were proposed as anchors for

assessment in determining a global score of severity and improve-

ment/deterioration. In a non-intervention study among individuals

with DS (

n

= 90, M age = 18.23, SD = 23.27), the CGI was conducted

with the ADAMS, CELF-2, CELF-4, BRIEF-P and VABS-II. Descriptive

and comparative analyses were performed.

Results

At screening, the CGI-S speech, social functioning, and

non-compliant domains correlated positively with ADAMS Social

avoidance (

r

= 0.400, 0.272 and 0.294, respectively) supporting con-

struct validity. The CELF negatively correlated with CGI-S Speech

(

r

= –0.469,

P

= 0.037). The CGI-I correlated negatively with the

VABS-II at Day 1, W4 and W24.

Conclusions

The CGI developed for Down syndrome (DS) is a valid

clinical outcome measure. It offers a number of advantages includ-

ing established utility in clinical research, sensitivity to change, and

consistency with neurocognitive measures in DS.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.773

EW656

Are there clinical and care differences

in real care intensity among patients

in general hospitals suffering from

psychiatric comorbidity?

J. Valdes-Stauber

1 ,

, S. Bachthaler

2

1

Zentrum für Psychiatrie Südwürttemberg, Psychosomatic Medicine,

Ravensburg, Germany

2

Zentrum für Psychiatrie Südwürttemberg Germany, Head Physician,

Psychosomatics, Ravensburg, Germany

Corresponding author.

Background

According to literature, about 30–40% of individuals

admitted in general hospitals suffer from psychiatric comorbidity.

Consultation-liaison services (CLS) cover internationally 1–10% of

admissions and are able to improve care quality, treatment adher-

ence and to reduce length of stay.

Objectives

To assess possible clinical and care differences

between individuals with and without psychiatric comorbidity as

well as differences among principal diagnostic groups.

Aims

To find out, whether individuals suffering fromspecific psy-

chiatric diagnoses show a higher degree of care needs held by a

CLS.

Method

Retrospective, ethical approved full-survey assessment

(

n

= 2940) over three years (2012–2014). ICD-10 diagnoses, clinical

factors and care variables were considered. Group differences were

calculated by means of chi-square and ANOVA as well as Scheffé

post-hoc estimation. Associations were conducted by means of

multivariate regression as well as logistic regression models.

Results

Individuals suffering from psychiatric comorbidity (48%

of sample) were seldom primarily oncologic patients (30%),

they showed more distress (DT = 6.5), more performance lim-

itations (ECOG = 1.38), and less functionality (GAF = 59.6). They

received more contacts by CLS (1.95), more cumulative treatment

time (89.7min), and more psychopharmacological interventions

(30.6%). People suffering from recurrent depressive and somato-

form disorders received much more contacts and treatment time

than other diagnostic groups. Age was negatively associated with

care intensity.

Conclusions

CLS services are able to offer differentiated psy-

chiatric care depending on diagnoses. Individuals suffering from

classical psychiatric disorders received rather treatment as

usual, oncologic patients more psychotherapeutic interventions.

Depressive as well as somatoformpatients seem to needmore time

and personal resources.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.774

EW657

Psychopathology, temperament and

suicide risk in adolescence: The role of

early traumatic experience

P. Venturini

1 ,

, F . F

agioli

2 , L. S

apienza

1 , T. B

oldrini

2 , 3 ,

E. Bonaccorsi

2 , D.

Erbuto

1 , F. M

ontebovi

1 , P. G

irardi

1 ,

M. Pompili

1

1

Department of Neurosciences, Mental Health and Sensory

Functions, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza

University of Rome, Rome, Italy

2

Department of Mental Health, Rome E Health Trust. Adolescents

Department Via Plinio 31, Rome, Italy

3

Department of Dynamic and Clinical Psychology. Sapienza

University of Rome, Rome, Italy

Corresponding author.

Introduction

Previous researches showed that adolescents are at

high risk of suicide. Suicide is a trans-nosographic phenomenon

regardless of psychiatric diagnosis. Trauma is an important risk

factor for suicide and young help-seeking patients usually refer

traumatic experiences, especially during childhood.

Objectives

The objective of this study is to assess the relationship

between traumatic experience and suicide risk comparing adoles-

cents with suicide risk with adolescents without suicide risk.

Aims

To investigate correlations between trauma, psychopathol-

ogy and suicide risk in a sample of young help-seeking outpatients.

Methods

We recruited 99 outpatients aged between 14 and 21

years admitted to department for prevention and early intervention

in adolescence of Rome. We administered psychometric instru-

ments exploring suicide risk (SHSS, BHS), prodromal (SIPS/SOPS),

affective and anxious symptoms (HAM-A, HAM-D,MRS), child

abuse (CTQ) and experiences of depersonalization (CDS).

Results

Sample is composed of 31 men and 68 women. A total

of 34.3% had mood disorder. A total of 28.3% reported history of

emotional neglect, 20.2% emotional abuse, 9.15 sexual abuse, 5.1%

physical neglect, 9,1% sexual abuse, 4% physical abuse. More than

30% of patients were at increased suicide risk. Depressive, irritable,

anxious and cyclothymic temperament was associated with sui-

cide risk. Patients with suicide risk had higher score at HAM-D

(

t

63 = 2.65;

P

= 0.01), CDS (

t

63 = 2.77;

P

= 0.007), in CTQ (

t

63 = 3.20;

P

= 0.002) and BHS (

t

63 = 3.23;

P

= 0.002).

Conclusions

Adolescents with suicide risk, compared with those

without, reportedmore frequently early traumatic experiences and

psychiatric symptoms. Early traumatic experiences constitute a risk

factor for both suicide risk and psychiatric symptoms during ado-

lescence.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.775

EW658

Sexual well-being among a

cross-national sample of older adults

S. von Humboldt

, I. Leal , A. Monteiro

ISPA-Instituo Universitário, William James Research Center, Lisbon,

Portugal

Corresponding author.

Introduction

Sexual well-being (SWB) has been an ignored

dimension that may contribute to successful aging.