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S352

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

syndrome ago. It has a history of cannabis, cocaine and alcohol since

he was thirteen and remains abstinent for more than six months

ago. Differential diagnosis arises between amotivational toxic syn-

drome, reactive depressive symptoms to the disease and negative

symptoms for chronic psychotic process. Finally diagnosed with

paranoid schizophrenia and is included in the program of first psy-

chotic episodes.

Today the productive symptoms disappeared and remain negative

though with less intensity achieving an improvement in overall

activity.

Conclusions

Consumption of toxic influences the development of

a chronic psychotic process that may appear years later, becom-

ing a etiological and maintainer factor, not only if its consumption

continue, but other effects that occur long term amotivational syn-

drome and worsening prognosis.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Further readings

Luca, et al. Negative dimension in psychiatry. Amotivational syn-

drome as a paradigm of negative symptoms in substance abuse.

Simon Zhornitsky, et al. Research article psychopathology in

patients with substance use disorder and substance-induced with-

out psychosis. J Addict 2015.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.994

EV10

Cannabis and cyclical vomiting

M. Canseco Navarro

, M. Canccino Botello ,

M.M. Machado Vera , J.M. Hernández Sánchez , F. Molina López

Consorcio Hospital General Universitario, Conselleria de Sanitat,

Valencia, Spain

Corresponding author.

Introduction

Traditionally,

cannabis is associated with

antiemetic action after acute consumption. However, in 2004

the cannabinoid hyperemesis as paradoxical effect of chronic

users, after years of exposure described.

Objectives

Description of the cannabinoid hyperemesis.

Method

OLOGYA case is presented.

Results

Clinical case of a woman who repeatedly comes to the

emergency service because of abdominal, nausea and vomiting

pain.

This is cyclical and hardly controllable. The gastroenterology ser-

vice studied in depth with negative results. She was followed up by

mental health borderline personality disorder and she consumed

cannabis at an early age, 20–30 joints daily.

When she reaches abstinence in short periods, ceases digestive dis-

comfort. However, aprece digestive symptoms with each relapse.

The present case showed improvement with cessation of cannabis

so it probably was the cannabinoid hyperemesis syndrome.

Conclusions

The cannabinoid hyperemesis is characterized by

recurrent episodes of nausea, vomiting, abdominal pain, and

chronic cannabis use. Temporary relief is achieved with hot baths.

Ceases when abstinence is achieved. It is a clinical entity that does

not have much information and requires further study.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Further readings

Sullivan S. Cannabinoid hyperemesis. Can J Gastroenterol

2010;24(5):284–5.

Enriqueta Ochoa-Mangado, Gimenez Monica Jimenez, Salvador

Vadillo, Augustine Star Madoz-Gurpide. Vomitos side to cannabis

cyclic. Gastroenterol Hepatol 2009;32(6):406–9.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.995

EV11

Clinical features of kinesthetic

hallucinations in cocaine-dependent

patients

C. Roncero

1 , 2 ,

, L. Rodriguez-Cintas

1 , 2

, L. Grau-López

1 , 2

,

E. Ros-Cucurull

2

, J. Perez-Pazos

1

, C. Barral

1 , 2

, F. Palma-Alvarez

1

,

V. Barrau

1

, A. Herrrero-Fernandez

1

, N. Vela

1

, D. Romero

1

,

M. Sorribes

1

, M. Casas

2 , 3

, A. Egido

1

, J. Alvaros

1

, C. Daigre

1 , 4

1

Vall d’Hebron University Hospital, Adddiction and Dual Diagnosis

Unit. Psychiatry, Barcelona, Spain

2

Universidad Autonoma de Barcelona, Psychiatry, Barcelona, Spain

3

Vall d’Hebron University Hospital, Psychiatry, Barcelona, Spain

4

Vall Hebron Institut Reserca, Addiction, Barcelona, Spain

Corresponding author.

Introduction

Legal and illegal drugs can cause psychotic symp-

toms, in cocaine-dependent patients the prevalence of these

symptoms may reach 86% (Vorspan, 2012). It is estimated that

13–32% of cocaine-dependent patients have kinaesthetic halluci-

nations (Siegel, 1978; Mahoney, 2008; Roncero, 2012).

Objectives

To compare the prevalence of substance-induced psy-

chotic symptoms and compare the use of welfare/social resources

and social adjustment among cocaine-dependent patients (CD) and

other substances dependences (OtherD).

Methods

Two hundred and six patients seeking treatment at

the Addictions and Dual Diagnosis Unit of the Vall d’Hebron.

Patients were assessed by ad hoc questionnaire designed to collect

demographic data and psychotic symptoms associated with con-

sumption, a record of the care/social resources used by the patient

and the scale of social adaptation (SASS). A descriptive and bivariate

analysis of the data was performed.

Results

CD were 47.1% vs. 52.9% OtherD (66.1% alcohol, 17.4%

cannabis, 8.3% opioid, 8.3% benzodiazepines/other drugs). Of

cocaine dependent-patients, 65.6% present psychotic symptoms vs.

32.1% for the OtherD. Different exhibiting psychotic symptoms are:

self-referential (69.7% vs. 30.7%), delusions of persecution (43.4%

vs. 12.2%), hallucinations (49.4% vs. 14.3%), auditory hallucinations

(43.5% vs. 11.4%), visual hallucinations (30.4% vs. 5.7%) and kinaes-

thetic hallucinations (7.2% vs. 2.9%).

Cocaine-dependent patients significantly use more health care

resources in reference addiction unit (76.3% vs. 62.4%,

P

:.035)

and infectious diseases (22.7% vs. 5.5%,

P

:.000) and justice-related

(50.5% vs. 26 resources 0.6%;

P

:1.001) and less resources andmental

health (25.8% vs. 43.1%;

P

:.013).

Regarding social adaptation, no differences were found in the SASS.

Kinaesthetic hallucinations do not appear to be related to a greater

use of resources and in social adaptation.

References not available.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.996

EV12

Risk factors for accidents among

cocaine-dependent patient seeking

treatment

C. Roncero

1 , 2 ,

, L. Rodriguez-Cintas

1 , 2

, C. Daigre

1

, J. Alvarez

3

,

C. Barral

2

, A. Abad

1

, V. Nina

1

, A. Herrero-Fernandez

1

,

L. Grau-López

1 , 2

, C. Barral

1 , 2

, J. Pérez-Pazos

1

,

E. Ros-Cucurrull

1 , 2

, L. Rodriguez-Martos

1

, M. Casas

3 , 4

1

Vall d’Hebron University Hospital, Addiction and Dual Diagnosis

Unit, Psychiatry, Barcelona, Spain

2

Universidad Autonoma de Barcelona, Psychiatry, Barcelona, Spain

3

Facultad de Medicina, Pharmacology, Valladolid, Spain

4

Vall d’Hebron University Hospital, Psychiatry, Barcelona, Spain

Corresponding author.