European Psychiatry - Volume 33 - March 2016

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S354 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Conclusions As the management of compulsive behaviours is
complex, physician should better assess and recognize psycholog-
ical personality aspect, collecting patients’ complete history, also
testing them psychometrically, and paying more attention to an
eventual treatment (both psychological and pharmacological).
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV15
The impact of addictive disorders on
the HIV and syphilis coinfection
E. Chumakov ∗, N. Petrova , I. Smirnova
1 Saint Petersburg State University, Department of Psychiatry and
Narcology, Saint-Petersburg, Russia
2 Saint Petersburg State University, Department of Psychiatry and
Narcology, Saint Petersburg, Russia
3 Saint Petersburg State University, Department of Infectious Diseases
– Epidemiology and Dermatovenerology, Saint Petersburg, Russia
∗ Corresponding author.
Introduction One of the main risk factors for both HIV-infection
and syphilis is addictive behavior.
The objective of the study was to determine the impact of addic-
tions on the HIV and syphilis coinfection.
Method Sixty-five HIV-infected patients with syphilis were
examined by a clinical method.
Results The sample included 45 men (average age 32.09 ± 9.83)
and 20 women (average age 31.7 ± 5.97). All patients were char-
acterized by risky behavior. Seventy-one percent of men belonged
to the category of men who have sex with men (MSM). Eighty-five
percent of women had drug dependence (as compared to 61% for
men who have sex with women (MSW) and 19% for МSМ; P < 0.05).
Women were more likely to have opiate dependence (P < 0.001; as
compared to men). We revealed a high incidence of drug addiction
and alcoholismwith the prevalence of dependence on opioids (F11;
55.0%; 7.7%), polysubstance use (F19; 25.0%; 23.1%) and alcoholism
(F10; 50.0%; 61.25%) amongwomen andMSWrespectively (P < 0.05
as compared toMSM). Only 50% of women and 23% of MSWwere in
remission. MSM regularly consumed stimulants and cannabinoids
without developing dependence.
Conclusions Injecting drug use is typical of women and MSWand
plays a leading role in the risk factors for HIV infection and syphilis.
Addictive behavior among MSM increases risky sexual behavior
and thus influences infection with HIV and syphilis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV16
The structure of mental disorders in
HIV-infected patients with syphilis
E. Chumakov ∗, N. Petrova , I. Smirnova
1 Saint Petersburg State University, Department of Psychiatry and
Narcology, Saint-Petersburg, Russia
2 Saint Petersburg State University, Department of Psychiatry and
Narcology, Saint Petersburg, Russia
3 Saint Petersburg State University, Department of Infectious
Diseases- Epidemiology and Dermatovenerology, Saint Petersburg,
Russia
∗ Corresponding author.
Introduction There are no data in literature on mental disorders
in HIV-infected patients with syphilis.
The objective of the study was to determine the structure of mental
disorders in HIV-infected patients with syphilis.
Method Sixty-five HIV-infected patients with syphilis were
examined by a clinical method.
Results The sample included 45 men (average age 32.09 ±9.83)
and 20 women (average age 31.7 ± 5.97). We divided the sample
into three comparison groups (according to the importance of risk
factors): women, men who have sex with men (MSM), and men
who have sex with women (MSW).
Mental disorders were identified in most patients (83%). Opiate
dependence (F11, ICD-10) was established in 55% of women (7.7%
for MSW, 0% in MSM; P < 0.001). The dependence on multiple
drug use (F19) was revealed with nearly the same frequency in
women (25.0%) and inMSW (23.1%); but far less frequently inMSM
(3.2%; P = 0.047). The dependence on stimulants (F15) was found in
women (5.0%) and MSM (6.3%). The dependence on alcohol (F10)
was more common among MSW (61.5%) and women (50.0%) (9.4%
in MSM; P < 0.001). 20% of women had Depressive episode (F32).
Adjustment disorders (F43) were found much more often in men
(43.8% for MSM; 38.5% for MSW; 10% for women; P = 0.035). Per-
sonality disorders (F60) were found in all the groups.
Conclusions We revealed a high incidence of addictions among
women and MSW. Affective disorders were represented by depres-
sive episode in women and adjustment disorders in men.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV17
A comprehensive overview on Kratom
E. Cinosi ∗, P. Simonato , D. Singh , F.S. Bersani ,
G. Piazzon , M. Lupi , S. Marini , M. Kapitány-Fövény ,
J. Farkas , Z. Demetrovics , A. Roman-Urrestarazu ,
B. Vicknasingam , J.H. Li , W.J. Yu , R. Santacroce ,
T. Acciavatti , G. Martinotti , M. Di Giannantonio , O. Corazza
1 University “G. D’ Annunzio”, Neuroscience- Imaging and Clinical
Sciences, Chieti, Italy
2 University of Hertfordshire, School of Life and Medical Sciences,
Hatfield, United Kingdom
3 Universiti Sains Malaysia, Centre for Drug Research, USM, Malaysia
4 Sapienza University of Rome, Department of Neurology and
Psychiatry, Rome, Italy
5 Semmelweis University, Faculty of Health Sciences, Budapest,
Hungary
6 Eötvös Loránd University, Institute of Psychology, Budapest,
Hungary
7 University of Cambridge, Department of Psychiatry, Cambridge,
United Kingdom
8 Kaohsiung Medical University, School of Pharmacy, Kaohsiung,
Taiwan
∗ Corresponding author.
Kratom (Mitragyna speciosa Korth) is a tropical tree, indigenous to
South East Asia. Historically, the plant is locally used as a stimulant,
a remedy in traditional medicine and in social context. Imported
to Western countries, Kratom is classified as a novel psychoactive
substance (NPS).
A systematic review of the literature on Mitragyna speciosa and
its main constituents was carried by our international multidisci-
plinary group. Results were qualitatively analysed in three main
areas of interest: in-vitro and preclinical data on pharmacology
and behavioral effects, laboratoristic techniques for identifi-
cation/characterization, epidemiological/toxicological reports on
humans.
At present, there is no systematic data on the prevalence of Kratom
use in all the native countries, but it seems to be considerable.
In South-East Asia, Kratom, even if banned, might be still con-
sidered a better option than other illicit drugs, an alternative
opioid treatment, a “natural” remedy with no real social stigma
attached to its consumption. In parallel, this ethno-drug seems
to be popular in Western countries, largely unregulated, easily
available on the Internet. Kratom pharmacology appears to be