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S354

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Conclusions

As the management of compulsive behaviours is

complex, physician should better assess and recognize psycholog-

ical personality aspect, collecting patients’ complete history, also

testing them psychometrically, and paying more attention to an

eventual treatment (both psychological and pharmacological).

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.999

EV15

The impact of addictive disorders on

the HIV and syphilis coinfection

E. Chumakov

1 ,

, N. Petrova

2

, I. Smirnova

3

1

Saint Petersburg State University, Department of Psychiatry and

Narcology, Saint-Petersburg, Russia

2

Saint Petersburg State University, Department of Psychiatry and

Narcology, Saint Petersburg, Russia

3

Saint Petersburg State University, Department of Infectious Diseases

– Epidemiology and Dermatovenerology, Saint Petersburg, Russia

Corresponding author.

Introduction

One of the main risk factors for both HIV-infection

and syphilis is addictive behavior.

The objective of the study was to determine the impact of addic-

tions on the HIV and syphilis coinfection.

Method

Sixty-five HIV-infected patients with syphilis were

examined by a clinical method.

Results

The sample included 45 men (average age 32.09

±

9.83)

and 20 women (average age 31.7

±

5.97). All patients were char-

acterized by risky behavior. Seventy-one percent of men belonged

to the category of men who have sex with men (MSM). Eighty-five

percent of women had drug dependence (as compared to 61% for

men who have sex with women (MSW) and 19% for

М

S

М

;

P

< 0.05).

Women were more likely to have opiate dependence (

P

< 0.001; as

compared to men). We revealed a high incidence of drug addiction

and alcoholismwith the prevalence of dependence on opioids (F11;

55.0%; 7.7%), polysubstance use (F19; 25.0%; 23.1%) and alcoholism

(F10; 50.0%; 61.25%) amongwomen andMSWrespectively (

P

< 0.05

as compared toMSM). Only 50% of women and 23% of MSWwere in

remission. MSM regularly consumed stimulants and cannabinoids

without developing dependence.

Conclusions

Injecting drug use is typical of women and MSWand

plays a leading role in the risk factors for HIV infection and syphilis.

Addictive behavior among MSM increases risky sexual behavior

and thus influences infection with HIV and syphilis.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1000

EV16

The structure of mental disorders in

HIV-infected patients with syphilis

E. Chumakov

1 ,

, N. Petrova

2

, I. Smirnova

3

1

Saint Petersburg State University, Department of Psychiatry and

Narcology, Saint-Petersburg, Russia

2

Saint Petersburg State University, Department of Psychiatry and

Narcology, Saint Petersburg, Russia

3

Saint Petersburg State University, Department of Infectious

Diseases- Epidemiology and Dermatovenerology, Saint Petersburg,

Russia

Corresponding author.

Introduction

There are no data in literature on mental disorders

in HIV-infected patients with syphilis.

The objective of the study was to determine the structure of mental

disorders in HIV-infected patients with syphilis.

Method

Sixty-five HIV-infected patients with syphilis were

examined by a clinical method.

Results

The sample included 45 men (average age 32.09

±

9.83)

and 20 women (average age 31.7

±

5.97). We divided the sample

into three comparison groups (according to the importance of risk

factors): women, men who have sex with men (MSM), and men

who have sex with women (MSW).

Mental disorders were identified in most patients (83%). Opiate

dependence (F11, ICD-10) was established in 55% of women (7.7%

for MSW, 0% in MSM;

P

< 0.001). The dependence on multiple

drug use (F19) was revealed with nearly the same frequency in

women (25.0%) and inMSW (23.1%); but far less frequently inMSM

(3.2%;

P

= 0.047). The dependence on stimulants (F15) was found in

women (5.0%) and MSM (6.3%). The dependence on alcohol (F10)

was more common among MSW (61.5%) and women (50.0%) (9.4%

in MSM;

P

< 0.001). 20% of women had Depressive episode (F32).

Adjustment disorders (F43) were found much more often in men

(43.8% for MSM; 38.5% for MSW; 10% for women;

P

= 0.035). Per-

sonality disorders (F60) were found in all the groups.

Conclusions

We revealed a high incidence of addictions among

women and MSW. Affective disorders were represented by depres-

sive episode in women and adjustment disorders in men.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1001

EV17

A comprehensive overview on Kratom

E. Cinosi

1 ,

, P. Simonato

2

, D. Singh

3

, F.S. Bersani

4

,

G. Piazzon

2

, M. Lupi

1

, S. Marini

1

, M. Kapitány-Fövény

5

,

J. Farkas

6

, Z. Demetrovics

6

, A. Roman-Urrestarazu

7

,

B. Vicknasingam

3

, J.H. Li

8

, W.J. Yu

8

, R. Santacroce

1

,

T. Acciavatti

1

, G. Martinotti

1

, M. Di Giannantonio

1

, O. Corazza

2

1

University “G. D’ Annunzio”, Neuroscience- Imaging and Clinical

Sciences, Chieti, Italy

2

University of Hertfordshire, School of Life and Medical Sciences,

Hatfield, United Kingdom

3

Universiti Sains Malaysia, Centre for Drug Research, USM, Malaysia

4

Sapienza University of Rome, Department of Neurology and

Psychiatry, Rome, Italy

5

Semmelweis University, Faculty of Health Sciences, Budapest,

Hungary

6

Eötvös Loránd University, Institute of Psychology, Budapest,

Hungary

7

University of Cambridge, Department of Psychiatry, Cambridge,

United Kingdom

8

Kaohsiung Medical University, School of Pharmacy, Kaohsiung,

Taiwan

Corresponding author.

Kratom (Mitragyna speciosa Korth) is a tropical tree, indigenous to

South East Asia. Historically, the plant is locally used as a stimulant,

a remedy in traditional medicine and in social context. Imported

to Western countries, Kratom is classified as a novel psychoactive

substance (NPS).

A systematic review of the literature on Mitragyna speciosa and

its main constituents was carried by our international multidisci-

plinary group. Results were qualitatively analysed in three main

areas of interest: in-vitro and preclinical data on pharmacology

and behavioral effects, laboratoristic techniques for identifi-

cation/characterization, epidemiological/toxicological reports on

humans.

At present, there is no systematic data on the prevalence of Kratom

use in all the native countries, but it seems to be considerable.

In South-East Asia, Kratom, even if banned, might be still con-

sidered a better option than other illicit drugs, an alternative

opioid treatment, a “natural” remedy with no real social stigma

attached to its consumption. In parallel, this ethno-drug seems

to be popular in Western countries, largely unregulated, easily

available on the Internet. Kratom pharmacology appears to be