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S240

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

Methods

We consecutively recruited 57 first-visit DSM-V OCD

patients (females = 66.7%; age range = 18–63 years) at the Psychi-

atric Outpatient Clinic of our University Hospital. These patients

were affected by severe OCD, as shown by a median (1st

quartile–3rd quartile) Yale-Brown Obsessive-Compulsive Scale

(Y-BOCS) score of 27.0 (23.0–32.5). We used the point-biserial

coefficient (

r

pbi

) to measure the correlation between psychopatho-

logical dimensions, as assessed with the Scale for the Rapid

Assessment of Psychopathology (SVARAD), and obsession sub-

types, as evaluated with the Y-BOCS.

Results

We found significant correlations (

P

-values < 0.05)

between: anger/aggressiveness dimension and aggressive, con-

tamination, and sexual obsessions; apprehension/fear dimension

and contamination, religious, and somatic obsessions; sad-

ness/demoralization dimension and contamination and somatic

obsessions; obsessiveness/iterativity dimension and all obses-

sion subtypes; impulsivity dimension and aggressive and sexual

obsessions; somatic concern/somatization dimension and con-

tamination and somatic obsessions. We also found, by using

the Mann-Whitney

U

-test, that OCD patients with comorbid

Obsessive-Compulsive Personality Disorder–but not Schizotypal

or Histrionic ones–showed higher levels (

P

< 0.05) of obsessive-

ness/iterativity and anger/aggressiveness than OCD patients

without the personality disorder.

Conclusions

Anger and other psychopathological dimensions

seem to be linked with specific obsession subtypes in OCD patients,

suggesting an association between these dimensions and OCD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.480

EW363

Does cognitive flexibility moderate

the relationship between disgust

sensitivity and contamination fear?

E. Powell

Ferndown, United Kingdom

High disgust sensitivity and poor cognitive flexibility have been

independently identified as contributing factors in the aetiology

of obsessive-compulsive disorder. This study looks at the rela-

tionship between contamination fear and disgust sensitivity in a

non-clinical population. In particular, at whether two moderat-

ing factors, cognitive flexibility and emotional reappraisal, have

a buffering influence. One hundred participants from an under-

graduate population completed a battery of questionnaires which

rated their disgust and level of contamination fear. They also com-

pleted a set-shifting task to assess cognitive flexibility and an

emotion regulation questionnaire. The mean age of the sample

was 21.4 years with 62% of the sample population being female.

SPSS 16 was used to correlate the main variables using Pear-

son’s correlation andmoderated regression, usingMODPROBE, was

used for analysis. Results confirmed previous findings that high

disgust sensitivity is significantly associated with contamination

fear (

P

< 0.01). In addition to this, both cognitive flexibility and

emotional reappraisal reduced the influence that disgust has on

an individual’s contamination fear. Cognitive flexibility and emo-

tion reappraisal were not found to be significantly correlated to

each other (

P

= 0.511), which suggest that these variables moderate

the relationship between disgust and contamination fear indepen-

dently of each other. Individuals with poor cognitive flexibility

and/or poor emotional reappraisal were found to have high lev-

els of contamination fear, which suggests that these two variables

may attenuate the relationship between disgust and contamina-

tion fear. Future implications of these findings have been discussed

although further research is needed to confirm these conclusions

in a clinical population.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.481

EW364

The comorbidity of cluster C

personality disorders in obsessive

compulsive disorder as a marker of

anxiety and depression severity

A. Pozza

1 ,

, S. Domenichetti

2

, G.P. Mazzoni

3

, D. Dèttore

4

1

University of Florence, Department of Experimental and Clinica

Medicine, Florence, Italy

2

Florence Healthcare Services, Department of Mental Health,

Florence, Italy

3

“Studi Cognitivi” Cognitive Psychotherapy and Research Center,

Postgraduate Program on Cognitive Psychotherapy, Florence, Italy

4

University of Florence, Department of Health Sciences, Florence,

Italy

Corresponding author.

Introduction

Comorbid Cluster C Personality Disorders (PDs) are

the most prevalent PDs in Obsessive-Compulsive Disorder (OCD).

Investigating clinical correlates associated to OCD with Cluster C

PDs may allow identifying tailored treatment strategies.

Objectives

The current study examined whether OCD with

comorbid cluster C PDs is associated to more severe OCD symp-

toms, anxiety and depression relative to OCDwith comorbid cluster

B PDs or OCD alone.

Methods

Two hundred thirty-nine patients with OCD were

included (mean age = 35.64, SD = 11.08, 51% females). Seventeen

percent had a comorbid Cluster C PD, 8% had a comorbid Cluster

B PD, and 75% had OCD alone. The Structured Clinical Interview

for Axis II Disorders, Yale-Brown Obsessive Compulsive Scale, Beck

Anxiety Inventory, Beck Depression Inventory-II were adminis-

tered.

Results

Patients with comorbid Cluster C PDs reported more

severe depression and anxiety than those with comorbid Cluster

B PDs (

F

= 10.48,

P

< 0.001) or with OCD alone (

F

= 9.10,

P

< 0.001).

Patients with comorbid Cluster C PDs had more severe OCD symp-

toms than those with OCD alone but not than those with comorbid

Cluster B PDs (

F

= 3.12,

P

< 0.05).

Conclusions

OCDwith Cluster C PDs could be a subtypewithmore

severe anxiety and depression. These findings could be explained

with the fact that Cluster C PDs are characterized by behaviours,

which can be seen as maladaptive attempts to cope with anxiety

and depression. Tailored treatment strategies for OCD with comor-

bid Cluster C PDs are discussed to target co-occurring anxiety and

depression.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.482

EW365

Group cognitive behavioural therapy

for outpatients with

obsessive-compulsive disorder in a

psychiatric service in Italy

A. Pozza

1 ,

, S. Domenichetti

2

, A. Tanini

2

, E. Ruggieri

2

,

D. Dèttore

3

1

University of Florence, Department of Experimental and Clinical

Medicine, Florence, Italy

2

Healthcare Services of Florence, Department of Mental Health,

Florence, Italy

3

University of Florence, Department of Health Sciences, Florence,

Italy

Corresponding author.