European Psychiatry - Volume 33 - March 2016

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S416 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Introduction Decreased quality of life can be observed in both
bipolar and schizoaffective disorder, more so in the acute episode,
but also during remission.
Objectives To assess the quality of life of bipolar and schizoaffec-
tive patients after at least 6 months of euthymia.
Methods Eighty-nine outpatients diagnosed with bipolar disor-
der and 74 outpatients diagnosed with schizoaffective disorder,
according to ICD 10 diagnostic criteria and 90 healthy subjects
were selected for this study. The assessment of the subjects took
place during remission (present for at least 6 months), between
2009 and 2015. As work instruments we used the SF-36 Scale for
assessing quality of life and the HAMD Scale (Hamilton Depression
Rating Scale) andYMRS Scale (YoungMania Rating Scale) to confirm
remission.
Results The schizoaffective group scored lower regarding quality
of life when compared to the bipolar group. Both affective disor-
der groups showed significantly lower quality of life scores when
compared to the healthy control group.
Conclusions Both affective disorders have a significant negative
impact on quality of life even during remission. Schizoaffective
patients seem to have a lower quality of life than bipolar patients.
Interventions regarding education, care planning, social interven-
tions and interventions towards improving physical health should
aid in the improvement of the quality of life.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV208
Religious delusions in bipolar and
schizoaffective patients: A Romanian
sample
R.S. Romosan ∗, F. Romosan , V.R. Enatescu , A. Draghici ,
L. Dehelean Podea redicean apava
C. Giurgi-Oncu
1 “Victor Babes” University of Medicine and Pharmacy, Neuroscience,
Timisoara, Romania
2 Vasile Goldis West University of Arad, Psychiatry, Arad, Romania
∗ Corresponding author.
Introduction Religious delusions have regularly been reported
throughout history in patients with schizophrenia, affective
psychoses, complex partial seizure disorders and drug-induced
psychoses.
Objectives The purpose of the study was to identify potential dif-
ferences regarding demographic and clinical features of bipolar and
schizoaffective patients presenting religious delusions.
Method Thirty-five inpatients diagnosed with bipolar disorder
and 32 inpatients diagnosed with schizoaffective disorder, accord-
ing to ICD 10 diagnostic criteria, were selected for this study. The
assessment of the subjects took place between 2012 and 2015.
We divided the subjects into two samples: with and without reli-
gious delusions. Socio-demographic (age, sex, education, marital
status) and clinical data were analysed. The Brief Psychiatric Rat-
ing Scale (BPRS) and the Global Assessment of Functioning Scale
(GAF) were used to assess current psychopathology and global
functioning.
Results Among the schizoaffective patients, 17.8% and 16.9% of
bipolar patients presented religious delusions. Similarly, in both
samples, patients with religious delusion were older, more fre-
quently unmarried women, had graduated high school, had higher
BPRS total scores and higher BPRS psychotic cluster scores and had
lesser global functioning.
Conclusions Religious delusions were not related to any of the
two diagnostic groups but were associated, in both bipolar and
schizoaffective patients, with an increased severity of psychotic
positive symptoms and had worse global functioning.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV209
Efficacy of electroconvulsive therapy
(ECT) in the first trimester of
pregnancy: A case of manic patient
M. Sahin ∗ ahmelikoglu Onur , N. Fıstıkcı , C. Karsıdag
Bakırkoy Research and Training Hospital for Psychiatry Neurology
and Neurosurgery, Psychiatry, Istanbul, Turkey
∗ Corresponding author.
Women with bipolar disorder have a risk for symptom exacerba-
tion during pregnancy. ECT is an appropriate option for psychiatric
symptoms during pregnancy although it is often neglected. We
report a case of bipolar, week 6 of gestation woman who discon-
tinued medication in the second week of pregnancy but resumed
pharmacotherapy with ECT due to manic episode that recurred
during the first trimester.
Case A 23-year-old female, with a history of one psychiatric
hospitalization (a manic episode three years ago) and lithium
900mg/day, olanzapine 5mg/day use for three years until week
2 of gestation admitted to clinic with complaints of decreased need
for sleep, increased speech, lability of emotions, religious delusions
and irritability for the last two weeks. Young Mani Score (YMS)
was 32. ECT, which was considered as the first-line treatment, was
not carried out due to low pseudocholinesterase (2401). There-
fore, olanzapine was reinstated with a dose of up to 20mg/day.
Although olanzapine, irritability still continued. Therefore, medica-
tion was switched from olanzapine to haloperidol 15mg/day and
quetiapine 25mg/day. Due to persistent symptoms, after neces-
sary consultations and family approval taken, shewas administered
6 sessions of ECT with oral haloperidole, although low pseudo-
cholinesterase. Since 7 YMS, she was discharged with haloperidol
15mg/day, biperiden 4mg/day and quetiapine 25mg/day.
Conclusion This case highlights the effectiveness of ECT in mania
during the first trimester of pregnancy. We suggest that ECT might
be considered as a valid option formanic episode during pregnancy.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV210
Evolution of bipolar disorder in dual
pathology
C.F. Silvia ∗, M.D. Sánchez García , A. Gómez Peinado , P. Cano Ruiz
HNSPS, PSIQUIATRIA, Albacete, Spain
∗ Corresponding author.
Introduction The substance use is common among people with
a diagnosis of bipolar disorder. In addition, alcoholism and bipolar
disorder coexist with a high frequency. This association is higher in
men than in women, and this consumption is the factor that most
strongly influences the hospitalization.
Objectives To analyze the clinical, epidemiological, diagnostic
approach and evolution of bipolar disorder and alcoholism.
Methods Review of the subject on recent articles of alcoholism in
bipolar disorder.
Results The stages of mania associatedwith alcohol consumption
up to 40% of cases and aremore common at this stage that in depres-
sive. This association is greater than that which occurs between
alcoholism and schizophrenia or depression. Patients with bipo-
lar disorder who have mixed and irritative states and those with
rapid cycling have a prevalence of alcohol consumption and sub-
stance use higher than those who do not use substances. It has also
been observed that the consumption of alcohol and substance use