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S362

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

and a poly-drug excessive drinking and smoking group, on an objec-

tive measure of PM.

Methods

A between-subjects design will be used to compare

three groups: (1) a group of excessive drinkers who do not smoke;

(2) a group of smokers who do not drink excessively and (3) a group

of excessive drinkers who also smoke. The Cambridge Prospec-

tive Memory Task will measure both time and event based PM;

and two self-reports will measure covariates of substance use and

everyday mood (since these can impact upon PM independent of

smoking/drinking status).

Results

Descriptive statisticswill be applied to observe the trends

across all three groups with regards the covariates andmain depen-

dent measures of time and event based PM. A series of ANOVAs

will be applied to determine significance across the groups on the

covariates and on the main dependent measures.

Conclusions

The conclusions and implications will be presented

at the conference, along with suggestions for future research.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1023

EV39

Relation between substance of abuse

and demographic characteristics,

medical and psychiatric history in

patients with substance related

disorders

S. Herrera

1 ,

, A. Riquelme

1

, T. León

2

, M. Babul

2

1

Pontificia Universidad Católica de Chile, School of Medicine,

Santiago, Chile

2

Pontificia Universidad Católica, School of Medicine, Department of

Psyquiatry, Santiago, Chile

Corresponding author.

Introduction

Substance related disorders is a problem of global

concern because of the high prevalence and costs for patients and

society. In one of the latest surveys, 52% of the American popu-

lation reported being current alcohol drinkers and 6.3% admitted

being heavy drinkers. In addition, 9.4% are illicit drug users, being

marijuana the most commonly used.

Objectives

To determine whether there is a relation between the

substance of abuse and the demographic characteristics, medical

and psychiatric comorbidities of patients with substance use dis-

order.

Patients and methods

This correlational study examined data

of 218 patients with substance use disorder (DSM-5), that con-

sulted at the Addiction Unit of “Red de Salud, Pontificia Universidad

Católica de Chile”, between April 2012 and September 2015. Data

included: demographics, medical and psychiatric history, labora-

tory and imaging tests.

Results

Out of all the patients, 57% suffered from alcohol use dis-

order, whereas 21% abused of marijuana, 20% of cocaine and 8% of

benzodiazepines. There was a correlation between alcohol use dis-

order and being over 40 years of age, being separated and having

higher educational studies. For marijuana, being under 40 years of

age, being single and having no medical comorbidities. For cocaine,

not being single. For benzodiazepines, being over 40 years of age,

being separated and having medical comorbidities. All of these cor-

relations were statistically significant.

Conclusion

These results emphasize on the complexity of these

patients and on the important contrast created between age,

marital status, level of education and prevalence of comorbidity

depending on the abused substance.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1024

EV40

Demographic characteristics, medical

and psychiatric history of patients

with prescription opioid use disorder

S. Herrera

1 ,

, A. Riquelme

1

, T. León

2

, M. Babul

2

1

Pontificia Universidad Católica, School of Medicine, Santiago, Chile

2

Pontificia Universidad Católica, School of Medicine. Department of

Psyquiatry, Santiago, Chile

Corresponding author.

Introduction

Over the past two decades the prescription of opioid

analgesics has increased with a subsequent escalating in prescrip-

tion opioid misuse. It is estimated that 4.5 million (2.5%) of the

United States of America population abuse of pain relievers; opioids

are among the most commonly.

In Chile there are few reports about the prevalence of opioid use

disorder.

Objectives

The aim of this study is to describe the demographic

characteristics, medical and psychiatric comorbidity of patients

that suffer from opioid addiction.

Patients and methods

This transversal study examined data of 7

patients with opioid use disorder (OUD; DSM-5) that consulted

at the addiction unit of “Red de Salud, Pontificia Universidad

Católica de Chile”, betweenNovember 2013 andOctober 2015. Data

included: demographics, medical and psychiatric history, labora-

tory and imaging tests.

Results

Of all the patients, 57% were men, 25 to 67 years of

age, 43% between 35-40 years; 57% were married; 57% had com-

pleted studies at university. 43% had also alcohol use disorder,

28% marijuana, 28% cocaine and 28% benzodiazepines than in most

cases began before OUD. In addition; 57% had medical comorbid-

ity among which stand out obesity (17%), osteoarthritis (17%) and

chronic low back pain (17%). Eighty-three percent require hospi-

talization. Twenty-eight percent had abnormal liver tests and one

patient had positive hepatitis B core antibody. Opioids used were:

morphine(14%), codeine (43%), tramadol (42%).

Conclusion

These results emphasize on the misuse of prescrip-

tion opioids analgesics, the complexity of patients with OUD and

the prevalence of other substance use disorder that precedes and

accompany OUD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1025

EV41

Predictors of quality of life in

opiate-dependent individuals

undergoing methadone maintenance

treatment

C. Hornillos

, M. Crespo

Universidad Complutense de Madrid – School of Psychology,

Personalidad – Evaluación y Tratamientos Psicológicos I

Personalidad – Evaluación y Psicología Clínica, Pozuelo de Alarcón,

Spain

Corresponding author.

Introduction

Quality of Life (QoL) is an important outcome vari-

able in Methadone Maintenance Treatment (MMT) for opiate

dependence. Previous research has focused on demographic vari-

ables, treatment features, drug use and physical and mental health

as possible predictors of QoL in this condition but interest in gen-

uinely psychological variables (skills and personal repertoires) has

been lacking. Experiential Avoidance (EA), the tendency to behave

in order to decrease some kind of internal distress, has a strong rela-

tionship to psychological disorders and holds promise as a potential

predictor of QoL.