European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348 S299
Table 3 Correlations between quality of life and coping strategies.
*P < 0.05; **P < 0.01; ***P < 0.001.
EW524
Self-stigma and quality of life in
Psychopharmacs treated outpatients
with schizophrenia and related
disorders - A cross-sectional study
M. Holubova ∗, J. Prasko , K. Latalova , M. Ociskova ,
A. Grambal , D. Kamaradova , K. Vrbova , R. Hruby
1 Faculty of medicine and dentistry- Palacky university Olomouc-
university hospital Olomouc, department of psychiatry, Olomouc,
Czech Republic
2 Regional hospital Liberec, department of psychiatry, Liberec, Czech
Republic
3 Psychiatric outpatient department, Martin, Slovakia
∗ Corresponding author.
Introduction Self-stigma is a maladaptive psychosocial phe-
nomenon that can disturb self-image and quality of life in
psychiatric outpatients and may lead to dysphoria, social isolation
and reduced adherence to treatment.
Objectives Self-stigma and QoL could be reflected as important
factors for patients, who suffer from schizophrenia spectrum dis-
orders, their caregivers and mental health specialists. Focus on
reducing the self-stigma in supportive and educational therapy
could be an important factor in promoting a higher QoL.
Aims Current research moved attention to the relationship
between demographic data, the severity of symptoms, self-stigma
and quality of life in schizophrenic outpatients compared to the
QoL in healthy controls.
Methods Patients who met ICD-10 criteria for schizophrenia
spectrum disorder were recruited in the study. The Quality of
Life Satisfaction and Enjoyment questionnaire (Q-LES-Q), Internal-
ized Stigma of Mental Illness (ISMI) and severity of the disorder
measured by objective and subjective Clinical Global Impression
severity scales (CGI) were assessed.
Results One hundred and nine psychotic patients and 91 healthy
controls participated in the study. Compared to the control group,
there was a lower QoL and a higher score of self-stigma in psy-
chotic patients. We found the correlation between the self-stigma,
duration of disorder and QoL. The level of self-stigma correlated
positively with total symptom severity score and negatively with
the QoL. Stepwise regression analysis revealed that the objective
severity and self-stigma score were significantly associated with
the quality of life
Conclusions Our study suggests a negative impact of self-stigma
level on the quality of life in patients suffering from schizophrenia
spectrum disorders.
Table 1 Description of the sample, demographic and clinical data.
Table 2 Relation between Q-les-Q domains and facets of ISMI.
*P < 0.05; **P < 0.01; ***P < 0.001.