European Psychiatry - Volume 33 - March 2016

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S714 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
EV1142
Internalized stigma, negative
symptoms and global functioning in
schizophrenia
O.O. Capatina ∗, I.V. Miclutia
University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca,
Neuroscience Psychiatry, Cluj-Napoca, Romania
∗ Corresponding author.
Introduction Negative symptoms (NS) of schizophrenia were
usually described as a unitary construct and as a separable domain
of pathology; however recent studies suggest, that they encompass
2 separable domains: Diminished Expression (DE) and Avolition-
Apathy (AA). Research into the relationship between internalized
stigma and NS have yielded mixed results up to present.
Objective The objectives of this study was to assess the factor
structure of NS and to examine the relationship between these
factors and internalized stigma, global functioning and sociodemo-
graphic characteristics.
Aims The broad aim of this study was to gather greater under-
standing of the relationship between internalized stigma, NS and
global functioning.
Methods A sample of 50 consecutive subjects were recruited
from outpatient psychiatric hospitals meeting the criteria for
schizophrenia according to ICD-10. The patients were evaluated
using the Positive and Negative Symptoms Scale (PANSS), Negative
Symptoms Assessment-16 items (NSA-16), Global Assessment of
Functioning (GAF), Clinical Global Impression-Severity Scale (CGI-
s), Internalized Stigma of Mental Illness Scale (ISMI) and were
interviewed to assess sociodemographic characteristics.
Results A two-factor structure for the domain of NSwas found: an
AA and DE profile group. AA and DE subgroups significantly differed
on clinically relevant external validators and greater resistance to
stigma is related to both fewer AA and DE symptoms in people with
schizophrenia.
Conclusions Our findings suggest that the different subdomains
of NS can be identified within the broader diagnosis of schizophre-
nia and that they should be analyzed as distinct domains and that
stigma resistance can be a possible intervention target to amelio-
rate NS.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1143
Hypergraphia: Illustrating clinical
pictures
L. Carvalhão Gil ∗, A. Ponte , J. Gama Marques
Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisboa, Portugal
∗ Corresponding author.
Introduction Hypergraphia is an extensive writing tendency
sometimes coupled with hyperreliogiosity and atypical sexuality,
completing a syndrome described by Waxman and Geschwind
in 1975 during interictal phases of patients with temporal lobe
epilepsy. Nevertheless, it may arise from any temporolimbic lesion,
usually in the right hemisphere, in contrast to the schizophreniform
psychosis more often seen in left-sided lesions.
Objective A review on the lateralizing significance of tem-
porolimbic lesions, highlighting the (un)specificity of hyper-
graphia, after a case report concerning a patient with both
hypergraphia and schizophreniform psychosis.
Methods Analyse patient’s clinical records and PubMed review,
using hypergraphia, epilepsy and psychosis as keywords.
Results We report a 74-year-old male admitted due to aggres-
siveness. The patient had a traumatic brain injury in his 20s
with secondary left temporal epilepsy. He lived in a psy-
chiatric asylum, for almost 40 years, with the diagnosis of
schizophrenia, showing fluctuant atypical sexual behavior. After
being transinstitutionalized to community nursing-home he devel-
oped meningoencephalitis, leading to medication change and
behavior relapse. He showed viscosity, circumstantiality, soliloquy,
euthymic mood and normal cognition. He wrote profusely, e.g. lists
of various categories and letters to eminent clerics and politics. His
diary was scanned for illustrative purpose.
Conclusions Hypergraphia is an uncommon but easy to find
symptom that deserves the full attention of the clinician, especially
in the differential diagnosis between schizophreniform psychosis
and temporal epilepsy.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1144
Schizencephaly and psychosis: A case
report
L. Carvalhão Gil ∗, A. Ponte
Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisboa, Portugal
∗ Corresponding author.
Introduction Schizencephaly is a raremalformation of the central
nervous system, a congenital disorder of cerebral cortical develop-
ment resulting in the formation of abnormal unilateral or bilateral
clefts in the cerebral hemispheres that extends from the pial sur-
face to the ventricle. It oftenmanifests with partial seizures, mental
retardation and hemiparesis.
Objective To illustrate a rare case of association between psy-
chosis and schizencephaly and the implication of this association
for understanding the biology of the psychosis.
Methods A literature search was performed on PubMed database
using the key words schizencephaly, psychosis, brain diseases and
retrieved papers were selected according to their relevance. The
patient clinical record was reviewed.
Results The authors report a case of a 59-year-old male admitted
into a psychiatric hospital with insomnia, disorganized behavior
probably secondary to auditory hallucinations and mystic delu-
sions. He also reported epilepsy and strabismus inhis right eye since
his childhood and right facial paresis. A head CT scan revealed a
left deep cortico-ventricular parieto-occipital communication cor-
responding to schizencephaly.
Conclusions Considering the theory that schizophrenia is asso-
ciated with abnormal brain development, this case report may
provide an example of a neurodevelopment abnormality that man-
ifests as psychosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1145
The evolution of emotional
intelligence in schizophrenia: A
comparative study of two groups at
different times of the disorder
E. Chapela ∗ uintero orales Félix-Alcántara
J. Correas ómez-Arnau
1 Hospital Universitario Infanta Leonor, Psychiatry, Madrid, Spain
2 Fundación Psiformación, Psychiatry, Madrid, Spain
3 Psikids, Psychiatry, Madrid, Spain
4 Hospital del Henares, Psychiatry, Madrid, Spain
∗ Corresponding author.
Introduction People with schizophrenia show changes in the
skills related to emotional intelligence, but little is known about
the clinical course of these deficits. Few studies have examined the
evolution of emotional intelligence in schizophrenia patients.