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S714

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

EV1142

Internalized stigma, negative

symptoms and global functioning in

schizophrenia

O.O. Capatina

, I.V. Miclutia

University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca,

Neuroscience Psychiatry, Cluj-Napoca, Romania

Corresponding author.

Introduction

Negative symptoms (NS) of schizophrenia were

usually described as a unitary construct and as a separable domain

of pathology; however recent studies suggest, that they encompass

2 separable domains: Diminished Expression (DE) and Avolition-

Apathy (AA). Research into the relationship between internalized

stigma and NS have yielded mixed results up to present.

Objective

The objectives of this study was to assess the factor

structure of NS and to examine the relationship between these

factors and internalized stigma, global functioning and sociodemo-

graphic characteristics.

Aims

The broad aim of this study was to gather greater under-

standing of the relationship between internalized stigma, NS and

global functioning.

Methods

A sample of 50 consecutive subjects were recruited

from outpatient psychiatric hospitals meeting the criteria for

schizophrenia according to ICD-10. The patients were evaluated

using the Positive and Negative Symptoms Scale (PANSS), Negative

Symptoms Assessment-16 items (NSA-16), Global Assessment of

Functioning (GAF), Clinical Global Impression-Severity Scale (CGI-

s), Internalized Stigma of Mental Illness Scale (ISMI) and were

interviewed to assess sociodemographic characteristics.

Results

A two-factor structure for the domain of NSwas found: an

AA and DE profile group. AA and DE subgroups significantly differed

on clinically relevant external validators and greater resistance to

stigma is related to both fewer AA and DE symptoms in people with

schizophrenia.

Conclusions

Our findings suggest that the different subdomains

of NS can be identified within the broader diagnosis of schizophre-

nia and that they should be analyzed as distinct domains and that

stigma resistance can be a possible intervention target to amelio-

rate NS.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2127

EV1143

Hypergraphia: Illustrating clinical

pictures

L. Carvalhão Gil

, A. Ponte , J. Gama Marques

Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisboa, Portugal

Corresponding author.

Introduction

Hypergraphia is an extensive writing tendency

sometimes coupled with hyperreliogiosity and atypical sexuality,

completing a syndrome described by Waxman and Geschwind

in 1975 during interictal phases of patients with temporal lobe

epilepsy. Nevertheless, it may arise from any temporolimbic lesion,

usually in the right hemisphere, in contrast to the schizophreniform

psychosis more often seen in left-sided lesions.

Objective

A review on the lateralizing significance of tem-

porolimbic lesions, highlighting the (un)specificity of hyper-

graphia, after a case report concerning a patient with both

hypergraphia and schizophreniform psychosis.

Methods

Analyse patient’s clinical records and PubMed review,

using hypergraphia, epilepsy and psychosis as keywords.

Results

We report a 74-year-old male admitted due to aggres-

siveness. The patient had a traumatic brain injury in his 20s

with secondary left temporal epilepsy. He lived in a psy-

chiatric asylum, for almost 40 years, with the diagnosis of

schizophrenia, showing fluctuant atypical sexual behavior. After

being transinstitutionalized to community nursing-home he devel-

oped meningoencephalitis, leading to medication change and

behavior relapse. He showed viscosity, circumstantiality, soliloquy,

euthymic mood and normal cognition. He wrote profusely, e.g. lists

of various categories and letters to eminent clerics and politics. His

diary was scanned for illustrative purpose.

Conclusions

Hypergraphia is an uncommon but easy to find

symptom that deserves the full attention of the clinician, especially

in the differential diagnosis between schizophreniform psychosis

and temporal epilepsy.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2128

EV1144

Schizencephaly and psychosis: A case

report

L. Carvalhão Gil

, A. Ponte

Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisboa, Portugal

Corresponding author.

Introduction

Schizencephaly is a raremalformation of the central

nervous system, a congenital disorder of cerebral cortical develop-

ment resulting in the formation of abnormal unilateral or bilateral

clefts in the cerebral hemispheres that extends from the pial sur-

face to the ventricle. It oftenmanifests with partial seizures, mental

retardation and hemiparesis.

Objective

To illustrate a rare case of association between psy-

chosis and schizencephaly and the implication of this association

for understanding the biology of the psychosis.

Methods

A literature search was performed on PubMed database

using the key words schizencephaly, psychosis, brain diseases and

retrieved papers were selected according to their relevance. The

patient clinical record was reviewed.

Results

The authors report a case of a 59-year-old male admitted

into a psychiatric hospital with insomnia, disorganized behavior

probably secondary to auditory hallucinations and mystic delu-

sions. He also reported epilepsy and strabismus inhis right eye since

his childhood and right facial paresis. A head CT scan revealed a

left deep cortico-ventricular parieto-occipital communication cor-

responding to schizencephaly.

Conclusions

Considering the theory that schizophrenia is asso-

ciated with abnormal brain development, this case report may

provide an example of a neurodevelopment abnormality that man-

ifests as psychosis.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2129

EV1145

The evolution of emotional

intelligence in schizophrenia: A

comparative study of two groups at

different times of the disorder

E. Chapela

1 ,

, J. Q

uintero

1 , 2 , 3 , I. M

orales

3 , M.

Félix-Alcántara

1 ,

J. Correas

2 , 4 , J. G

ómez-Arnau

4

1

Hospital Universitario Infanta Leonor, Psychiatry, Madrid, Spain

2

Fundación Psiformación, Psychiatry, Madrid, Spain

3

Psikids, Psychiatry, Madrid, Spain

4

Hospital del Henares, Psychiatry, Madrid, Spain

Corresponding author.

Introduction

People with schizophrenia show changes in the

skills related to emotional intelligence, but little is known about

the clinical course of these deficits. Few studies have examined the

evolution of emotional intelligence in schizophrenia patients.