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S710

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Introduction

Emotion regulation (ER) efficiency dwells among

the most pressing issues of contemporary psychology and psychi-

atry. Further development of the methods of reliable assessments

for ER makes it the task of current importance.

Objective

To modify Rosenzweig Picture-Frustration Test for the

study of ER in health and in disease.

Methods

In the initial stage of testing participants had to look

through a succession of Rosenzweig’s pictures, and select poten-

tially traumatizing situations.

In the second stage they answered the following questions:

– what would you say in this particular situation?

– what would you have in mind, saying this?

– could you think of an answer that would taper down the

traumatizing character of the situation in your own perception?

(Zinchenko, Pervichko, 2014).

A total of 85 patients with stress-induced hypertension (mean age

was 45.9

±

2.8) and 82 healthy subjects (mean age was 44.9

±

3.1)

took part in the study.

Results

We came to distinguish among four classes of ER strate-

gies: internal, cognitively non-mediated; internal, cognitively

transforming; external, cognitively non-mediated; and external,

cognitively transforming (Pervichko, 2015). Hypertensive patients

significantly more frequently than healthy subjects reveal wider

set of emotionally grave events (19.8% vs 11.2%,

P

< 0.001), they

are more prone to rumination, disasterization (19.0% vs 11.1%,

P

< 0.001) and suppression in display of their emotions (31.9% vs

20.2%,

P

< 0.001). The patients will seldom employ the strategy

of interactive subject–subject transformations; their capability to

actualize new meanings in traumatic situations is diminished.

Conclusions

Application of the described modification of Rosen-

zweig Picture-Frustration Test allows to distinguish and classify

various ER strategies, and to demonstrate peculiarities in ER related

behaviour of hypertensive patients as opposed to healthy subjects.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2115

EV1131

New methodologies for faster study of

new psychoactive substances: A

proposal

P. Quintana Mathé

1 , 2 ,

, M. Grifell

1 , 2 , 3

1

Hospital del Mar Medical Research Institute, Grup de Recerca en

Addiccions, Barcelona, Spain

2

Associació Benestar i Desenvolupament, Energy Control, Barcelona,

Spain

3

Parc de Salut Mar, Institut de Neuropsiquiatria i Addiccions,

Barcelona, Spain

Corresponding author.

Introduction

New psychoactive substances (NPS) are substances

that have recently become available, and are not worldwide reg-

ulated. They often intend to mimic the effect of controlled drugs,

becoming a public health concern. In 2014, 101 substances were

reported for the first time in the EU, whichmay require to be studied

and risk-assessed by the scientific community. The EMCDDA rec-

ognizes it as an emerging topic where research is most needed, as

the scientific community is struggling to keep pace with the speed

at which new substances appear. On the one hand, case reports

and internet-based surveys are quickly published but do not pro-

vide enough evidence to guide clinical decisions. On the other hand,

classical high-reliability methodologies such as Cohort and Clinical

studies take too long and their cost is too high to be of much use

for the study of NPS. We propose an intermediate methodology to

tackle this unmet need.

Rationale

González and colleagues described a set of highly edu-

cated, experimental users of NPS with extensive knowledge and

consumption of substances. These users usually look for drug

checking of the substances they intend to consume. We suggest

we could benefit from the collaboration of such users, and the pos-

sibility of obtaining analytical confirmation, to retrieve information

about NPS in a quick and reliable fashion.

Outline of methodology

Recluting of subjects that submit NPS to a

drug checking facility. Analysis of the samples for analytical confir-

mation. Check inclusion criteria and propose inclusion in the study.

Give structured forms for reporting effects and adverse events.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2116

Schizophrenia

EV1132

Self-continuity across time in

schizophrenia: An exploration of

phenomenological and narrative

continuity in the past and future

M. Allé

1 ,

, A. D’Argembeau

2

, P. Schneider

1

, J. Potheegadoo

1

,

R. Coutelle

3

, J.M. Danion

1

, F. Berna

1

1

Inserm, U1114, Strasbourg, France

2

University of Liège, Psychology Department, Liège, Belgium

3

Psychotherapy center of Nancy, Autism Ressources Center, Laxou,

France

Corresponding author.

Disorders of the self, such as the “loss of continuity” of the self

in time, are a core symptom of schizophrenia, but one, which is

still poorly understood. In the present study, we investigated two

complementary aspects of self-continuity, namely phenomenolog-

ical and narrative continuity, in 27 patients with schizophrenia,

and compared themwith 27 control participants. Participants were

asked to identify 7 important past events and to narrate a story

taken from their life that included these events. They were then

asked to imagine 3 important events thatmight happen in their per-

sonal future and to build a narrative of their future life. Thememory

vividness of these important life-events and the proportion of

self-event connections in the narratives were used as a measure

of phenomenological and narrative continuity, respectively. Our

results showed that the difficulty for patients to construct vivid

representations of personally significant events was observed in

both temporal directions, past and future. Patients’ ability to estab-

lish explicit connections between personal events and attributes

of self in life narratives was also impaired, but only in the case of

past narratives. Our results yield a fresh understanding of the cog-

nitive mechanisms of self-disorders in schizophrenia. The clinical

and therapeutic implications of these findings are discussed.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2117

EV1133

Population pharmacokinetic

modeling and simulations of

dopamine Dd2 receptor occupancy of

long-acting intramuscular

risperidone-ISM

J. Llaudó

1 , L. A

nta

1 , I. A

yani

1 ,

, J. M

artínez-González

1 ,

I. Gutierro

2 , R. F

aelens

3 , J. W

inkler

3 , E. S

noeck

3

1

Laboratorios Farmacéuticos Rovi-S.A., Medical Department, Madrid,

Spain