European Psychiatry - Volume 33 - March 2016

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S718 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
been included in a delirium of persecution in 13 patients, delirium
of bewitchment (7 patients), mystical religious (n = 4) and finally
in apart of delusions of greatness ( n = 6) so as to follow a single
assignment: to fight terrorism.
Conclusion Delusions focused on the topic of DAECH were
observed frequently among young patients and formed an integral
part of especially persecution delirium, reflecting the collective fear
of this phenomenon.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1155
Analysis of the duration of untreated
illness (DUI) in the first episode
psychosis Program (FEP) in AGS South
Granada
B. Girela Serrano ∗, M. Guerrero Jiménez ,
C.M. Carrillo de Albornoz Calahorro , J.A. Rodrigo Manzano ,
O.B. Martínez García
Hospital Santa Ana Motril, Psiquiatría, Motril, Granada, Spain
∗ Corresponding author.
Introduction Duration of untreated illness (DUI) has been consid-
ered as a relevant variable used tomeasure the degree of disabilities
that are associated with psychotic disorders. In this paper we
describe a cluster of patientswith a DUI superior to 1 year according
to their symptoms and sociofamiliar functioning.
Methods We compare a groupwith a DUI superior to 1 year (n = 7)
against a group with a DUI inferior to 1 year (n = 17).
Results The group with a DUI superior to 1 year showed an
average age of 4 years younger (21) as the duration of untreated
psychosis (DUP) of 1 to 3months in the 80% of cases and higher
percentage of unemployed or without occupation. The 60% were
derived fromprimary care, compared to the 17% of the other group.
Although the consumption of toxic substances was similar in both
groups, no toxic psychosis were found in comparison with the 35%
present in the group with a DUI inferior to 1 year. PANSS’ profile
scored more positive and less negative symptoms. Both have sim-
ilar general psychopathology. There were group differences in the
Social Functioning Scale (SFS) with lower scores in the superior
to 1 year DUI, in the following scales: Prosocial, Autonomy, Execu-
tion and Employment. The Global Assessment of Functioning (GAF)
gives an average of almost 8 points higher.
Discussion While the SFS shows significant differences in several
areas of social functioning, both PANSS ´profile and the family ques-
tionnaire do not support greater deterioration, as evidenced in the
GAF’s average score.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1156
Meta-analysis of the effectiveness of
the drug in the treatment of
schizophrenia
A. Golmohammadi Hafshejani ∗ Arizi Abedi
M. Shafiei Amiri
1 University of Isfahan, Clinical Psychology, Isfahafan, Iran
2 University Faculty of Humanities, University of Esfahan, Clinical
Psychology, Esfahan, Iran
3 Young Researchers Club, Azad University Roudehen, Clinical
Psychology, Rodehen, Iran
∗ Corresponding author.
Introduction In recent years, scientists have been looking for the
effects of the drug in the treatment of schizophrenia. In this meta-
analysis by integrating the results of various studies, shall specify
the size of treatment effect.
Aim The study is based on research using meta-analysis model,
the impact of drugs on the treatment of schizophrenia.
Methods For this purpose, nine of whichwere acceptable in terms
of methodology, and meta-analysis was performed on them.
Research tools Meta-analysis checklist was included.
Research findings The rate of drug treatment interventions on the
treatment of schizophrenia 2.41 respectively.
Conclusion The study showed the effect of treatments on the
interpretation of Cohen in the treatment of schizophrenia high.
Keywords Meta-analysis; Disorder; Schizophrenia; Drug
treatment
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1157
Psychosis-related polydipsia and
chronic hyponatremia – A case report
F. Gonc¸ alves Godinho ∗, A.L. Melo , S. Marques , D. Barrocas
Hospital Espírito Santo de Évora, Psychiatry and mental health,
Évora, Portugal
∗ Corresponding author.
Introduction Psychogenic polydipsia has an estimated preva-
lence of 6–20% in psychiatric population. Although first described
in the 1930s, there are few studies addressing this problem and
its management. The high water intake can lead to severe hypona-
tremia with a mortality rate high enough to merit clinical concern.
Aims Report a case of a schizophrenic patient with psychogenic
polydipsia and hyponatremia.
Methods Retrospective review of the clinical file and literature
research on this topic.
Results A 41-year-old man with a long-term schizophrenia pre-
sented to the emergency room (ER) with exacerbation of psychotic
symptoms. In the prior 24months, he had stopped medication and
began excessive water intake (5 to 10 L/day). He presented with
auditory hallucinations, passivity phenomena and persecutory and
other delusional thoughts that justified this behavior – “The water
will end; I have to stock it, like camels do”. Presently he had
an asymptomatic hyponatremia (128mg/dL), but 6months before
he had been admitted in the ER with vomiting, altered state of
consciousness and convulsions secondary to severe hyponatremia
(108mg/dL). During the present hospitalization, organic causes of
hyponatremia were excluded and he was started on behavioral
measures and antipsychotics. The psychotic symptoms improved
and there was no need for water restriction after the first week,
with restored natremia values on discharge.
Conclusions With this case report we intended to raise aware-
ness on this potentially fatal condition that despite its prevalence
has no defined diagnostic criteria, nor established controlled trials
concerning the effectiveness of treatments.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1158
Schizophrenia spectrum disorders:
Focus on social cognition and
empathy
C. Gramaglia ∗, E. Gattoni , G. Giovanna , S. Gili , A. Feggi ,
V. Binda , P. Prosperini , P. Zeppegno
1 University of Eastern Piedmont, Traslational Medicine, Novara, Italy
2 AOU “Maggiore della Carità”, S.C. Psichiatria, Novara, Italy
∗ Corresponding author.