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S488

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

3

Sapienza University of Rome, Department of Neurosciences-Mental

Health and Sensory Organs-Sapienza University of Rome-Rome-Italy,

Rome, Italy

4

Dermatology Unit-, Department of Neurosciences- Mental Health

and Sensory Organs- Sapienza University of Rome–Rome–Italy,

Rome, Italy

Corresponding author.

Introduction

Psoriasis has a significant impact on the mental and

emotional functioning.

Objective

It has been reported that the risk of psychiatric comor-

bidity increases with the severity of the disorder, and the most

frequent associations appear to be those with depression and anx-

iety.

Aims

To analyze the association between psoriasis, mental dis-

orders and suicidal ideation in a sample of patients affected by

psoriasis. To investigate the differences between psoriasis patients

and patients with other dermatologic diseases.

Methods

Participants were 242 consecutive patients (142

women and 100 men), 112 patients with psoriasis (46.3%), 77

with melanoma (31.8%) and 53 with allergy (21.0%). All patients

were administered a structured sociodemographic interview and

the following measures: the Hamilton Rating Scale for Depression

(HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A). We

also assessed current and previous suicidal ideation and previous

suicide attempts.

Results

Patients with psoriasis (compared to other groups of

patients) more frequently had a comorbid mood disorder (16.1%

vs 3.9% and 0.0%, respectively for patients with melanoma and

patients with allergy;

2

2

= 14.98;

P

< 0.001), past suicidal ideation

(33.9% vs 15.6% and 18.9%, respectively for patients withmelanoma

and patients with allergy;

2

2

= 2.05;

P

< 0.01) and attempts (6.3%

vs 0.0% and 0.0%, for the other groups of patients;

2

2

= 8.37;

P

< 0.05). Patients with psoriasis reported higher HAM-D scores

than melanoma patients.

Conclusions

The clinical evaluation of patients with psoriasis

should include the assessment of psychiatric comorbidities and the

routinely assessment of suicide risk.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1421

EV437

Apathy and impulse control disorders

association: A study in a sample of

Parkinson’s disease patients

N. Sáez-Francàs

1 ,

, N. Ramirez

1

, J. Alegre-Martin

2

,

O. De Fabregues

3 , J. A

lvarez-Sabin

3 , J. H

ernandez-Vara

3

1

Hospital Saint Rafael, Department of Psychiatry, Barcelona, Spain

2

Hospital Universitari Vall D ´hebron, Vall D ´hebron Institut de

Recerca, Internal Medicine, Barcelona, Spain

3

Hospital Universitari Vall D’hebron, Vall D’hebron Institut de

Recerca, Neurology, Barcelona, Spain

Corresponding author.

Introduction

Parkinson’s disease (PD) is a neurodegenerative dis-

order that is associated with a wide range of motor symptoms,

cognitive deficits and behavioral disorders. Apathy and impulse

control disorders (ICDs) are common in these patients and have

been considered opposite ends of a reward and motivation disor-

ders continuum.

Aim

To evaluate the association and impact of ICDs presence

on apathy symptoms in PDs patients, considering the influence of

other psychopathological symptoms on this association.

Methods

This is a cross-sectional, observational study in which

115 consecutive medicated PD patients without dementia (mean

age 61.22

±

13.5 years; 63.5% men) were recruited. All the

patients underwent a psychiatric and neurologic evaluation. Motor

dysfunction was assessed with the Unified Parkinson’s disease Rat-

ing Scale (UPDRS), ICDswere evaluatedwith theMinnesota Impulse

Control Disorders Inventory (MIDI) and apathy with the Lille Apa-

thy Scale (LARS). The Hamilton Depression scale (HAM-D). The

State-Trait Anxiety Inventory (STAI-S) and Barrat Impulsivity Scale

(BIS) were also administrated.

Results

Twenty-seven (23.5%) patients showed an ICD. Patients

with an ICD scored higher in apathy (

P

= 0.012), trait anxiety

(

P

= 0.003) and impulsivity (

P

= 0.008). There were no differences

in depressive symptoms. In the linear regression analysis, TCI was

associated with more severe apathy (

b

= 4.20,

t

= 2.15,

P

= 0.034).

Conclusions

ICDs and apathy are frequent in PD. Although ICDs

have been related with a hyperdopaminergic state and apathy with

low dopamine levels, the observed frequent association suggests

common etiopathological mechanisms.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1422

EV438

Seizure as a conversion symptom, a

case report

N. Salgado

1 ,

, S. Benavente

2

, B. Macias

1

, J.M. Coll

3

1

Hospital Dr. Rodriguez Lafora, Psiquiatria, Madrid, Spain

2

Hospital Universitario 12 de Octubre, Psiquiatria, Madrid, Spain

3

Hospital Unversitario la Paz, psiquiatria, Madrid, Spain

Corresponding author.

Introduction

Patients with conversive disorder could show atyp-

ical clinical presentations with neurological symptoms that are not

frequently seen currently.

Case Report

A 21-year-old female who was diagnosed of con-

versive disorder was admitted into a short-stay psychiatric unit

for two weeks to introduce treatment and receiving a diagno-

sis. She presented few seconds long seizures in members without

bitting her tongue and keeping control of sphincters, always sur-

rounded by relatives. A neurological study was made with CT

scan and electroencephalography and no evidences of neurologi-

cal abnormalities were found. Various treatments were used but

seizures went worse. Venlafaxine (150 mg/day) was prescribed

after hipothymc reactive symptoms were observed, which together

with pshycotherapy achieved clinical improvement in the two

months follow-up.

Discussion

Patients with conversive disorder don’t respond

appropriately to pharmacologic treatment. In order for patients to

understand the situation it is important to keep themupdated in an

empathic manner. It is important to exclude other causes.

Conclusions

A detailed psychopathological exploration should be

made in all conversive patients, to explore symptoms and comor-

bidities that could reveal new therapeutic treatment.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1423

EV439

Diabetes: Psychiatric and somatic

comorbidity

J.Á. Monforte Porto

1 , A.

San Román Uría

1 ,

, C . L

lanes Álvarez

1 ,

P. Herguedas Vela

2 , I.E.

Escuer Nú˜nez

2 , J.A

. Alcalá Due˜nas

3 ,

M.T. Conde Ledesma

4

1

Complejo Asistencial de Zamora. Hospital Provincial de Zamora,

Servicio de Psiquiatría, Zamora, Spain

2

Hospital Universitario de Burgos, Servicio de Endocrinología y

Nutrición, Burgos, Spain

3

Unidad de Rehabilitación Psiquiátrica, Secretaría de Salud de Nuevo

León, Monterrey, Mexico