European Psychiatry - Volume 33 - March 2016

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S488 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
3 Sapienza University of Rome, Department of Neurosciences-Mental
Health and Sensory Organs-Sapienza University of Rome-Rome-Italy,
Rome, Italy
4 Dermatology Unit-, Department of Neurosciences- Mental Health
and Sensory Organs- Sapienza University of Rome–Rome–Italy,
Rome, Italy
∗ Corresponding author.
Introduction Psoriasis has a significant impact on the mental and
emotional functioning.
Objective It has been reported that the risk of psychiatric comor-
bidity increases with the severity of the disorder, and the most
frequent associations appear to be those with depression and anx-
iety.
Aims To analyze the association between psoriasis, mental dis-
orders and suicidal ideation in a sample of patients affected by
psoriasis. To investigate the differences between psoriasis patients
and patients with other dermatologic diseases.
Methods Participants were 242 consecutive patients (142
women and 100 men), 112 patients with psoriasis (46.3%), 77
with melanoma (31.8%) and 53 with allergy (21.0%). All patients
were administered a structured sociodemographic interview and
the following measures: the Hamilton Rating Scale for Depression
(HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A). We
also assessed current and previous suicidal ideation and previous
suicide attempts.
Results Patients with psoriasis (compared to other groups of
patients) more frequently had a comorbid mood disorder (16.1%
vs 3.9% and 0.0%, respectively for patients with melanoma and
patients with allergy; 2
2 = 14.98; P < 0.001), past suicidal ideation
(33.9% vs 15.6% and 18.9%, respectively for patients withmelanoma
and patients with allergy; 2
2 = 2.05; P < 0.01) and attempts (6.3%
vs 0.0% and 0.0%, for the other groups of patients; 2
2 = 8.37;
P < 0.05). Patients with psoriasis reported higher HAM-D scores
than melanoma patients.
Conclusions The clinical evaluation of patients with psoriasis
should include the assessment of psychiatric comorbidities and the
routinely assessment of suicide risk.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV437
Apathy and impulse control disorders
association: A study in a sample of
Parkinson’s disease patients
N. Sáez-Francàs ∗, N. Ramirez , J. Alegre-Martin ,
O. De Fabregues lvarez-Sabin ernandez-Vara
1 Hospital Saint Rafael, Department of Psychiatry, Barcelona, Spain
2 Hospital Universitari Vall D ´hebron, Vall D ´hebron Institut de
Recerca, Internal Medicine, Barcelona, Spain
3 Hospital Universitari Vall D’hebron, Vall D’hebron Institut de
Recerca, Neurology, Barcelona, Spain
∗ Corresponding author.
Introduction Parkinson’s disease (PD) is a neurodegenerative dis-
order that is associated with a wide range of motor symptoms,
cognitive deficits and behavioral disorders. Apathy and impulse
control disorders (ICDs) are common in these patients and have
been considered opposite ends of a reward and motivation disor-
ders continuum.
Aim To evaluate the association and impact of ICDs presence
on apathy symptoms in PDs patients, considering the influence of
other psychopathological symptoms on this association.
Methods This is a cross-sectional, observational study in which
115 consecutive medicated PD patients without dementia (mean
age 61.22 ± 13.5 years; 63.5% men) were recruited. All the
patients underwent a psychiatric and neurologic evaluation. Motor
dysfunction was assessed with the Unified Parkinson’s disease Rat-
ing Scale (UPDRS), ICDswere evaluatedwith theMinnesota Impulse
Control Disorders Inventory (MIDI) and apathy with the Lille Apa-
thy Scale (LARS). The Hamilton Depression scale (HAM-D). The
State-Trait Anxiety Inventory (STAI-S) and Barrat Impulsivity Scale
(BIS) were also administrated.
Results Twenty-seven (23.5%) patients showed an ICD. Patients
with an ICD scored higher in apathy ( P= 0.012), trait anxiety
(P = 0.003) and impulsivity (P = 0.008). There were no differences
in depressive symptoms. In the linear regression analysis, TCI was
associated with more severe apathy ( b= 4.20, t = 2.15, P = 0.034).
Conclusions ICDs and apathy are frequent in PD. Although ICDs
have been related with a hyperdopaminergic state and apathy with
low dopamine levels, the observed frequent association suggests
common etiopathological mechanisms.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV438
Seizure as a conversion symptom, a
case report
N. Salgado ∗, S. Benavente , B. Macias , J.M. Coll
1 Hospital Dr. Rodriguez Lafora, Psiquiatria, Madrid, Spain
2 Hospital Universitario 12 de Octubre, Psiquiatria, Madrid, Spain
3 Hospital Unversitario la Paz, psiquiatria, Madrid, Spain
∗ Corresponding author.
Introduction Patients with conversive disorder could show atyp-
ical clinical presentations with neurological symptoms that are not
frequently seen currently.
Case Report A 21-year-old female who was diagnosed of con-
versive disorder was admitted into a short-stay psychiatric unit
for two weeks to introduce treatment and receiving a diagno-
sis. She presented few seconds long seizures in members without
bitting her tongue and keeping control of sphincters, always sur-
rounded by relatives. A neurological study was made with CT
scan and electroencephalography and no evidences of neurologi-
cal abnormalities were found. Various treatments were used but
seizures went worse. Venlafaxine (150 mg/day) was prescribed
after hipothymc reactive symptoms were observed, which together
with pshycotherapy achieved clinical improvement in the two
months follow-up.
Discussion Patients with conversive disorder don’t respond
appropriately to pharmacologic treatment. In order for patients to
understand the situation it is important to keep themupdated in an
empathic manner. It is important to exclude other causes.
Conclusions A detailed psychopathological exploration should be
made in all conversive patients, to explore symptoms and comor-
bidities that could reveal new therapeutic treatment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV439
Diabetes: Psychiatric and somatic
comorbidity
J.Á. Monforte Porto San Román Uría ∗ lanes Álvarez
P. Herguedas Vela Escuer Nú˜nez . Alcalá Due˜nas
M.T. Conde Ledesma
1 Complejo Asistencial de Zamora. Hospital Provincial de Zamora,
Servicio de Psiquiatría, Zamora, Spain
2 Hospital Universitario de Burgos, Servicio de Endocrinología y
Nutrición, Burgos, Spain
3 Unidad de Rehabilitación Psiquiátrica, Secretaría de Salud de Nuevo
León, Monterrey, Mexico