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S486

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Aims

Clarify the role of anxiety and depression in predicting new

cardiac events.

Methods

Two hundred and fifty-one consecutive patients com-

pleted the two-years follow-up. The presence of depression was

evaluated with the Primary Care Evaluation of Mental Disorders

(PRIME-MD) and its severity with the Hospital Anxiety and Depres-

sion Scale (HADS). Evaluations were collected at baseline, when

GRACE-score was calculated, and at 1, 2, 4, 6, 9, 12 and 24-months

follow-ups.

Results

Forty-two patients (16.7%) developed a second cardiac

event and, of these, eighteen (42.9%) had a previous depressive

episode. At Cox Regression, controlling for confounding clinical

variables (e.g. GRACE-score), developing a first-ever depressive

episode was a significant risk factor (OR = 2.38; 95%CI = 1.11–5.14;

P

= 0.027) whereas baseline anxiety was protective (OR = 0.56;

95%CI = 0.38–0.81;

P

= 0.002). The latter, moreover, moderated the

effect of incident depression on new cardiac events.

Conclusion

Our results confirm the well-established detrimental

effect of depression on cardiac prognosis and suggest clinicians to

keep in mind anxious symptoms when facing a patient at his/her

first ACS.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1415

EV431

Affective disorders in multiple

sclerosis

M. Said

1

, S. Ouanes

2 ,

, R. Nefzi

1

, A. Aissa

1

, H. Maatallah

1

,

H. Ben Ammar

1

, Z. El-Hechmi

1

1

Razi Hospital, Psychiatry F, Mannouba, Tunisia

2

Razi Hospital, Mannouba, Tunisia

Corresponding author.

Background

Psychiatric disorders have a remarquable frequency

in multiple sclerosis. The leading group of these disorders con-

sists of affective disorders. These psychiatric conditions canworsen

the outcome of multiple sclerosis, thus contributing to increase

the burden of the disease to both patients and relatives. Manag-

ing such a complicated situation needs a focus on the underlying

links between affective disorders and multiple sclerosis.

Objective

To examine the hypotheses proposed to explain the

high prevalence of affective disorders in patients with multiple

sclerosis.

Methods

Literature was reviewed using the Medline database

and the following keywords “bipolar disorder” “affective disorder”,

“mania” and “multiple sclerosis”.

Results

PubMed research returned 13 results. After manual

inspection, 10 articles were retained and examined. The cause of

the high comorbidity between multiple sclerosis and mood dis-

orders is regarded as being multifactorial: the medication used

in multiple sclerosis possibly inducing/exacerbating mood distur-

bances, the demyelinazing brain lesions which could bring about

depression or mania, genetic overlapping with affective disorders

and last the psychological reactions and adjustment difficulties to

the neurological handicap.

Conclusion

Despite the fact that the higher prevalence of affective

disorders in multiple sclerosis is well established, these disorders

still remain underdiagnosed and undertreated. A shift towards a

better assessment of the psychiatric comorbidity in multiple scle-

rosis patients and the optimal treatment of those disorders is

fundamental.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1416

EV432

Consultation liaison psychiatry in

Talavera’s hospital during the year

2014

M. Palomo Monge

1 ,

, D.C. Sandra

2

, A.L. Maria Fernanda

3

,

G.M. David

1

, T.G. Maria Fernanda

1

, D.D. Arántzazu

4

,

S.D.L.P. Silvia

3

, O.B. Rubén

1

, L.D.L. Beatriz

1

1

Hospital Nuestra Se˜nora del Prado, Psychiatry, 45600 Spain

2

Centro de Rehabilitación Psicosocial y Laboral, Psicology, Talavera

de la Reina, Spain

3

Hospital Nuestra Se˜nora del Prado, Family Medicine, 45600 Spain

4

Hospital General de Ávila, Psychiatry, Avila, Spain

Corresponding author.

Introduction

Analyze the number of interdepartmental consul-

tations carried out at Department of Psychiatry, Hospital Nuestra

Se˜nora del Prado from other areas of hospitalization during 2014.

Objectives

The goal is to evaluate the prevalence of psychiatric

disorders in patients who are hospitalized for other reasons, and

which services are needed the most.

Methods

Retrospective cross-sectional descriptive study. A

record of consultations carried out by the psychiatry service in 2014

was collected. The data were analyzed according to the origin of the

consultation service, the month when it was performed and the sex

of the patient. The monthly percentage of interconsultations and

the percentage represented by each interconsultation service were

calculated. They classified according to sex.

Results

In 2014, 211 interconsultations were carried out, 104

men and 86 women. Surgery 16, 11%, pneumology 13, 74%, internal

medicine 12, 32%, traumatology 8, 06%, digestive 7, 11%), I.C.U. 6,

64%, cardiology 6, 16%, hematology 5, 69%, oncology 5, 21%, pedi-

atrics 4, 27%, gynecology 2, 84%, emergency 1, 90%, palliative1, 90%,

endocrinology 1, 42%, urology 1, 42, nephrology 0, 95%, E.N.T. 0, 95%,

obstetrics 0, 47%, dermatology 0%, ophthalmology 0%, rheumatol-

ogy 0%. January 12, 8%, February 13%, March 9, 5%, April 6, 2%, May

5, 7%, June 8, 1%, July 6, 2%, August 4, 3%, September 8, 1%, October

12%, November 7, 6%, December 6, 2%.

Conclusions

Most of the interconsultations were carried out in

January, February and October. However, August was the least busy

month. The busiest service was the Surgery service, followed by the

Pneumology and Internal Medicine one. There were no intercon-

sultations of the Ophthalmology, Rheumatology and Dermatology

services. The consults were in demand mainly by men rather than

women.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1417

EV433

Psychological syndrome analysis

(Vygotsky – Luria School) in

psychosomatics: Clinical and

psychological study of patients with

mitral valve prolapse

E. Pervichko

1 ,

, Y. Zinchenko

1

, A. Martynov

2

1

Lomonosov Moscow State University, Faculty of Psychology,

Moscow, Russia

2

Moscow State University of Medicine and Dentistry, Faculty of

General Medicine, Moscow, Russia

Corresponding author.

Introduction

One of the dominant methodological principles of

Russian clinical psychology (the Vygotsky-Luria School) is the prin-

ciple of Psychological syndrome analysis (PSA). It can also be

heuristically applied to psychosomatics.