European Psychiatry - Volume 33 - March 2016

493 / 812

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S489
4 Complejo Asistencial de Zamora, Gerencia de Atención Primaria,
Zamora, Spain
∗ Corresponding author.
Introduction Diabetes mellitus (DM) has been associated with
major depressive disorder, schizophrenia, Alzheimer’s, Parkinson’s
and mild cognitive impairment. To determine the psychiatric and
somatic comorbidity in diabetic patients treated by our Liaison Psy-
chiatry Unit.
Methods Sociodemographic variables (age, sex, marital status,
place of residence) and clinical (somatic disease that motivates
the admission, comorbid somatic pathology, number of concomi-
tant somatic diseases, drug consumption and its type, psychiatric
history, previous psychiatric diagnosis, number of concomitant
psychiatric disorders).
Study Design Epidemiological study of 172 diabetic patients,
fromthe total of 906 consulted from1 January 2012 until 31Decem-
ber 2014.
Bioethical considerations The study complies with the principles
of justice, non-maleficence, autonomy and beneficence.
Results The average age is 72 years, 50% are women, 49.4% are
married, and 54.1% live in rural areas. Somatic diseases that most
frequently motivate admission at the hospital are the endocrine-
metabolic (14%), gastrointestinal (12%) and cardiovascular (12.2%).
A total of 32.5% of the sample have six comorbid somatic diseases
and 55.2% five. A percentage of 14.5 of patients recognize con-
sumption of toxic (cigarettes–12.2%–7.6% Alcohol). One hundred
and eight patients have a history of psychiatric disorders (62.8%),
especially anxiety disorders (28.4%), depression (14.5%) and organic
mental disorders (11.1%).
Conclusions There is a high psychiatric and somatic comorbidity
in diabetic patients, therefore it would be desirable early diagno-
sis and treatment to provide symptomatic control of both types of
pathologies.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV440
Use of atypical antipsychotics in
delirium
F. Sanchez ∗, M. Gutierrez Rodríguez , C. Moreno Menguiano ,
S.M. Ba˜non Gonzalez , P. Mu˜noz-Calero Franco
Hospital Universitario de Mostoles, Psychiatry, Mostoles, Spain
∗ Corresponding author.
Introduction Deliriumis a generally abrupt clinical onset inwhich
an impairment of attention and other brain functions occurs. May
occur in up to 40% of patients admitted to intensive care unit. Clin-
ical manifestations fluctuate throughout the day. Very different
symptoms such as disorientation, agitation, drowsiness, halluci-
nations may occur. It is particularly common in hospitals and the
elderly or patients with pre-existing disease. It should first rule out
systemic causes: infectious, metabolic, toxic and drug.
Methods The literature sourceswere obtained through electronic
search of articles in PubMed database of the last five years.
Discussion It was found atypical antipsychotic that are effective
and safe in treating. Haloperidol compared showed similar efficacy.
On the effectiveness of preventive treatment of this condition in
patients with risk factors the results are inconclusive.
Keywords Atypical antipsychotic; Delirium; Efficacy
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV441
Detection of perceptions and thoughts
that may lead to disruption of insulin
use in type 2 diabetes mellitus
patients
E. KIrlI- , T.D. Berkol , G. Sarıdogan , H. Erensoy ∗
1 Arnavutköy State Hospital, psychiatry, Istanbul, Turkey
2 Diskapi Yildirim Beyazit Research and Training Hospital-,
psychiatry, Istanbul, Turkey
3 Erenköy Mental and Neurological Disease Training and Research
Hospital, psychiatry, Istanbul, Turkey
4 Uskudar University, psychiatry, Istanbul, Turkey
∗ Corresponding author.
Aim In this study we aimed to identify the perceptions and
thoughts and their association with state/trait anxiety, depression
that may lead to resistance to insulin treatment in patients with
previously diagnosed type 2 diabetes mellitus (DM) patients in
order to facilitate their compliance with insulin treatment.
Method In this study, 120 patients were recruited with a pre-
vious type 2 DM diagnosis from the diabetes outpatient clinic.
Patients were evaluated with sociodemographic data, State-Trait
Anxiety Inventory, Problem Areas in Diabetes Scale, Insulin Treat-
ment Appraisal Scale, Beck Depression Inventory.
Results A majority of the patients were found to have resis-
tance for startinginsulin treatment. Most of the patientswho were
on other treatment alternatives reported that they wouldn’t use
insulin even if theywere prescribed insulin. A significant number of
patients reported negative perceptions and thoughts about insulin
treatment such as “insulin is a punishment”, “it is a shame to use
insulin where other people can see”. In women injection phobia
was significantly higher. Injection avoidance was significantly high
and was more related to feeling insufficient about administration
instead of worries about pain. Psychological resistance to insulin
was significantly related to depression but not associatedwith state
or trait anxiety levels. Lack of education and knowledge was found
to be another important contributor to this resistance.
Results Type 2 DM patients show psychological resistance to
insulin treatment due to negative perceptions and thoughts about
the treatment. Cognitive interventions targeting these factors may
be useful to overcome psychological insulin resistance and faciliate
glisemic control.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV442
Alexithymia and the incidence of
post-stroke depression
J.A. Su
Chang Gung Memorial Hospital - Chiayi, Department of Psychiatry,
Chiayi, Taiwan
Backgrounds Post-stroke depression (PSD) is the most frequent
neuropsychiatric consequence of stroke and often leads to poor
recovery and higher mortality. Identification of patients at high
risk of PSD and providing early interventions is important to allevi-
ate negative outcomes. Alexithymia is a construct characterized by
the inability to identify and describe emotions, and is also consid-
ered as a deficit in emotional processing. Alexithymia has a close
relationship to depression. Our study aimed to determine whether
alexithymia is a risk factor for the development of PSD.
Methods Patients with ischemic stroke admitted to a general
teaching hospital were enrolled in this six-month study. Demo-