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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S489

4

Complejo Asistencial de Zamora, Gerencia de Atención Primaria,

Zamora, Spain

Corresponding author.

Introduction

Diabetes mellitus (DM) has been associated with

major depressive disorder, schizophrenia, Alzheimer’s, Parkinson’s

and mild cognitive impairment. To determine the psychiatric and

somatic comorbidity in diabetic patients treated by our Liaison Psy-

chiatry Unit.

Methods

Sociodemographic variables (age, sex, marital status,

place of residence) and clinical (somatic disease that motivates

the admission, comorbid somatic pathology, number of concomi-

tant somatic diseases, drug consumption and its type, psychiatric

history, previous psychiatric diagnosis, number of concomitant

psychiatric disorders).

Study Design

Epidemiological study of 172 diabetic patients,

fromthe total of 906 consulted from1 January 2012 until 31Decem-

ber 2014.

Bioethical considerations

The study complies with the principles

of justice, non-maleficence, autonomy and beneficence.

Results

The average age is 72 years, 50% are women, 49.4% are

married, and 54.1% live in rural areas. Somatic diseases that most

frequently motivate admission at the hospital are the endocrine-

metabolic (14%), gastrointestinal (12%) and cardiovascular (12.2%).

A total of 32.5% of the sample have six comorbid somatic diseases

and 55.2% five. A percentage of 14.5 of patients recognize con-

sumption of toxic (cigarettes–12.2%–7.6% Alcohol). One hundred

and eight patients have a history of psychiatric disorders (62.8%),

especially anxiety disorders (28.4%), depression (14.5%) and organic

mental disorders (11.1%).

Conclusions

There is a high psychiatric and somatic comorbidity

in diabetic patients, therefore it would be desirable early diagno-

sis and treatment to provide symptomatic control of both types of

pathologies.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1424

EV440

Use of atypical antipsychotics in

delirium

F. Sanchez

, M. Gutierrez Rodríguez , C. Moreno Menguiano ,

S.M. Ba˜non Gonzalez , P. Mu˜noz-Calero Franco

Hospital Universitario de Mostoles, Psychiatry, Mostoles, Spain

Corresponding author.

Introduction

Deliriumis a generally abrupt clinical onset inwhich

an impairment of attention and other brain functions occurs. May

occur in up to 40% of patients admitted to intensive care unit. Clin-

ical manifestations fluctuate throughout the day. Very different

symptoms such as disorientation, agitation, drowsiness, halluci-

nations may occur. It is particularly common in hospitals and the

elderly or patients with pre-existing disease. It should first rule out

systemic causes: infectious, metabolic, toxic and drug.

Methods

The literature sourceswere obtained through electronic

search of articles in PubMed database of the last five years.

Discussion

It was found atypical antipsychotic that are effective

and safe in treating. Haloperidol compared showed similar efficacy.

On the effectiveness of preventive treatment of this condition in

patients with risk factors the results are inconclusive.

Keywords

Atypical antipsychotic; Delirium; Efficacy

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1425

EV441

Detection of perceptions and thoughts

that may lead to disruption of insulin

use in type 2 diabetes mellitus

patients

E. KIrlI-

1

, T.D. Berkol

2

, G. Sarıdogan

3

, H. Erensoy

4 ,

1

Arnavutköy State Hospital, psychiatry, Istanbul, Turkey

2

Diskapi Yildirim Beyazit Research and Training Hospital-,

psychiatry, Istanbul, Turkey

3

Erenköy Mental and Neurological Disease Training and Research

Hospital, psychiatry, Istanbul, Turkey

4

Uskudar University, psychiatry, Istanbul, Turkey

Corresponding author.

Aim

In this study we aimed to identify the perceptions and

thoughts and their association with state/trait anxiety, depression

that may lead to resistance to insulin treatment in patients with

previously diagnosed type 2 diabetes mellitus (DM) patients in

order to facilitate their compliance with insulin treatment.

Method

In this study, 120 patients were recruited with a pre-

vious type 2 DM diagnosis from the diabetes outpatient clinic.

Patients were evaluated with sociodemographic data, State-Trait

Anxiety Inventory, Problem Areas in Diabetes Scale, Insulin Treat-

ment Appraisal Scale, Beck Depression Inventory.

Results

A majority of the patients were found to have resis-

tance for startinginsulin treatment. Most of the patientswho were

on other treatment alternatives reported that they wouldn’t use

insulin even if theywere prescribed insulin. A significant number of

patients reported negative perceptions and thoughts about insulin

treatment such as “insulin is a punishment”, “it is a shame to use

insulin where other people can see”. In women injection phobia

was significantly higher. Injection avoidance was significantly high

and was more related to feeling insufficient about administration

instead of worries about pain. Psychological resistance to insulin

was significantly related to depression but not associatedwith state

or trait anxiety levels. Lack of education and knowledge was found

to be another important contributor to this resistance.

Results

Type 2 DM patients show psychological resistance to

insulin treatment due to negative perceptions and thoughts about

the treatment. Cognitive interventions targeting these factors may

be useful to overcome psychological insulin resistance and faciliate

glisemic control.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1426

EV442

Alexithymia and the incidence of

post-stroke depression

J.A. Su

Chang Gung Memorial Hospital - Chiayi, Department of Psychiatry,

Chiayi, Taiwan

Backgrounds

Post-stroke depression (PSD) is the most frequent

neuropsychiatric consequence of stroke and often leads to poor

recovery and higher mortality. Identification of patients at high

risk of PSD and providing early interventions is important to allevi-

ate negative outcomes. Alexithymia is a construct characterized by

the inability to identify and describe emotions, and is also consid-

ered as a deficit in emotional processing. Alexithymia has a close

relationship to depression. Our study aimed to determine whether

alexithymia is a risk factor for the development of PSD.

Methods

Patients with ischemic stroke admitted to a general

teaching hospital were enrolled in this six-month study. Demo-