European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S487
Objective To identify a psychosomatic syndrome in patients with
mitral valve prolapse (MVP).
Materials and methods We applied various techniques for a qual-
itative and statistical data analysis of clinical and psychological
study. We explored our patients’ individual personality profiles,
anxiety level (Spielberger et al., 1983), features of achievement
motivation (Heckhausen, 1963), emotion regulation strategies
(ERS) (Zinchenko, Pervichko, 2014; Pervichko, 2015), dynamics of
the patient’s emotional state in stress conditions, and degrees of
manifestation of MVP clinical symptoms. The study comprised 134
MVP patients, mean age was 24.8 ±1.2 years, and 73 healthy sub-
jects, mean age was 27.5 ± 1.3 years.
Results MVP patients proved to be more prone to emotional
stress; they were also inclined to choose less effective ERS as com-
pared to healthy subjects. ANOVA data revealed dependence of
intensity of such clinical symptoms as cardialgia, tensionheadaches
and psychogenic dyspnea on the degree of anxiety level and the
presence of dysfunctional ERS in MVP patients. The interpreta-
tion of the study results with PSA method suggested that the
patients’ psychological and clinical characteristics form into a psy-
chosomatic syndrome. The first syndrome-generating factor is the
presence of the approach – avoidance motivational conflict in
achievement settings. Dysfunctions of emotion regulation appear
as a second syndrome-generating factor in psychosomatic syn-
drome in MVP patients.
Conclusions PSA (the Vygotsky-Luria School) can be used as a
means to approach diagnostic and prognostic tasks in Clinical psy-
chology and Psychosomatic medicine.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV434
Low-FODMAP-diet in irritable bowel
syndrome offers benefits not only in
terms of gastrointestinal symptoms,
but also in terms of psychopathology
in the medium- and long-term
D. Piacentino ∗, S. Rossi , L. Piretta , D. Badiali , N. Pallotta ,
E.S. Corazziari
1 Sapienza-University of Rome, NESMOS Neuroscience-Mental
Health-and Sensory Organs Department, Rome, Italy
2 Sapienza-University of Rome, Department of Internal Medicine and
Medical Specialties, Rome, Italy
∗ Corresponding author.
Introduction Low-FODMAP (fermentable oligosaccharides, dis-
accharides, monosaccharides, and polyols) diets are strongly rec-
ommended to improve irritable bowel syndrome (IBS) symptoms.
They are also hypothesized to improve the psychopathological sta-
tus that often accompanies the syndrome. A study (Ledochowski
et al., 2000) suggested that the ingestion of FODMAPs affected neg-
atively the mood and that the elimination of dietary FODMAPs
improved depressive symptoms.
Objectives/aims We aimed to assess the levels of psychopathol-
ogy pre- and post-diet in IBS patients free of any severe
psychiatric disease (e.g., bipolar disorder, major depressive disor-
der, schizophrenia) or alcohol/substance abuse.
Methods We consecutively recruited 75 IBS outpatients (68%
females; age range = 21–68 years) at the Gastrointestinal Outpa-
tient Center of our University Hospital. They filled out the Symptom
Checklist-90-Revised (SCL-90-R), a visual analogue scale (VAS) to
rate the intensity of abdominal bloating/pain, and a 2-week diary
card registering the frequency of bloating/pain. Then, they were
blindly assigned to a low-FODMAP diet, a low-FODMAP gluten-
free diet and a control diet for 4 weeks. During the last 2 weeks they
filled out a 2nd diary card and rerated the intensity of bloating/pain.
Patients were reassessed after a 16-month follow-up. Independent
t-test, 2 test, and one-way ANOVA with Tukey post-hoc test were
used.
Results Baseline characteristics did not differ between the three
groups. Post-diet and at follow-up, the two low-FODMAP diets,
vs. the test diet, improved not only the intensity and frequency
of bloating/pain, but also the SCL-90-R GSI, anxiety, and phobic
anxiety scores (P-values < 0.05).
Conclusions The low-FODMAP diet may improve psychopathol-
ogy in IBS patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV435
EV435Life satisfaction and enjoyment
in medication-overuse headache
patients: The role of depression and
insomnia
M. Pompili ∗, G. Paolo , P. Martelletti
1 Rome, Italy
2 Sapienza, Department Nesmos, Roma, Italy
3 Sapienza, Department of Clinical and Molecular Medicine- Sapienza
University of Rome and Regional Referral Headache Centre-
Sant’Andrea Hospital–Rome–Italy, Roma, Italy
∗ Corresponding author.
Introduction Epidemiological research has documented a strong
association between medication-overuse headache (MOH)and
psychiatric disorders, emotional disturbances, and disordered per-
sonality traits, which are associated with worse outcomes, poorer
quality of life, and higher costs to the health care system.
Objectives Identifying risk factors for progression of headache
into MOH represents one of the most relevant public health prior-
ities and psychiatric comorbidity has been identified as a potential
factor related to chronic phases.
Aims The aim of the present study was to determine whether
depression and insomnia complaints were associated with satis-
faction and enjoyment with one’s own life in Medication-overuse
headache (MOH) patients, and whether insomnia complaints were
able to explain part of the variance of QoL explained by depression.
Methods Participants were 187 consecutive adult outpatients
admitted to the outpatient headache clinic. Patients were adminis-
tered the Quality of Life Enjoyment and Satisfaction Questionnaire
(Q-LES-Q), the Beck Depression Inventory–II (BDI-II), and the
Athens Insomnia Scale (AIS).
Results The BDI was associated with all the dimensions of the
Q-LES-Q, with more severe depression being associated indepen-
dently with lower satisfaction and enjoyment with one’s own life.
The AIS was independently and significantly associated only with
physical health, such that patients with more insomnia complaints
were 3.1 times (P < 0.001) more likely to report lower physical
health satisfaction.
Conclusions Our findings confirmed that MOH has a negative
impact on quality of life, and suggested that depression and insom-
niawere independently associatedwith satisfaction and enjoyment
of life in MOH patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV436
Psychiatric comorbidity and suicide
risk in patients with psoriasis
M. Pompili ∗, M. Innamorati , D. Erbuto , A. Costanzo
1 Rome, Italy
2 Università Europea di Roma, Department of Psychometrics, Roma,
Italy