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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S487

Objective

To identify a psychosomatic syndrome in patients with

mitral valve prolapse (MVP).

Materials and methods

We applied various techniques for a qual-

itative and statistical data analysis of clinical and psychological

study. We explored our patients’ individual personality profiles,

anxiety level (Spielberger et al., 1983), features of achievement

motivation (Heckhausen, 1963), emotion regulation strategies

(ERS) (Zinchenko, Pervichko, 2014; Pervichko, 2015), dynamics of

the patient’s emotional state in stress conditions, and degrees of

manifestation of MVP clinical symptoms. The study comprised 134

MVP patients, mean age was 24.8

±

1.2 years, and 73 healthy sub-

jects, mean age was 27.5

±

1.3 years.

Results

MVP patients proved to be more prone to emotional

stress; they were also inclined to choose less effective ERS as com-

pared to healthy subjects. ANOVA data revealed dependence of

intensity of such clinical symptoms as cardialgia, tensionheadaches

and psychogenic dyspnea on the degree of anxiety level and the

presence of dysfunctional ERS in MVP patients. The interpreta-

tion of the study results with PSA method suggested that the

patients’ psychological and clinical characteristics form into a psy-

chosomatic syndrome. The first syndrome-generating factor is the

presence of the approach – avoidance motivational conflict in

achievement settings. Dysfunctions of emotion regulation appear

as a second syndrome-generating factor in psychosomatic syn-

drome in MVP patients.

Conclusions

PSA (the Vygotsky-Luria School) can be used as a

means to approach diagnostic and prognostic tasks in Clinical psy-

chology and Psychosomatic medicine.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1418

EV434

Low-FODMAP-diet in irritable bowel

syndrome offers benefits not only in

terms of gastrointestinal symptoms,

but also in terms of psychopathology

in the medium- and long-term

D. Piacentino

1 ,

, S. Rossi

2

, L. Piretta

1

, D. Badiali

2

, N. Pallotta

2

,

E.S. Corazziari

2

1

Sapienza-University of Rome, NESMOS Neuroscience-Mental

Health-and Sensory Organs Department, Rome, Italy

2

Sapienza-University of Rome, Department of Internal Medicine and

Medical Specialties, Rome, Italy

Corresponding author.

Introduction

Low-FODMAP (fermentable oligosaccharides, dis-

accharides, monosaccharides, and polyols) diets are strongly rec-

ommended to improve irritable bowel syndrome (IBS) symptoms.

They are also hypothesized to improve the psychopathological sta-

tus that often accompanies the syndrome. A study (Ledochowski

et al., 2000) suggested that the ingestion of FODMAPs affected neg-

atively the mood and that the elimination of dietary FODMAPs

improved depressive symptoms.

Objectives/aims

We aimed to assess the levels of psychopathol-

ogy pre- and post-diet in IBS patients free of any severe

psychiatric disease (e.g., bipolar disorder, major depressive disor-

der, schizophrenia) or alcohol/substance abuse.

Methods

We consecutively recruited 75 IBS outpatients (68%

females; age range = 21–68 years) at the Gastrointestinal Outpa-

tient Center of our University Hospital. They filled out the Symptom

Checklist-90-Revised (SCL-90-R), a visual analogue scale (VAS) to

rate the intensity of abdominal bloating/pain, and a 2-week diary

card registering the frequency of bloating/pain. Then, they were

blindly assigned to a low-FODMAP diet, a low-FODMAP gluten-

free diet and a control diet for 4 weeks. During the last 2 weeks they

filled out a 2nd diary card and rerated the intensity of bloating/pain.

Patients were reassessed after a 16-month follow-up. Independent

t

-test,

2

test, and one-way ANOVA with Tukey post-hoc test were

used.

Results

Baseline characteristics did not differ between the three

groups. Post-diet and at follow-up, the two low-FODMAP diets,

vs. the test diet, improved not only the intensity and frequency

of bloating/pain, but also the SCL-90-R GSI, anxiety, and phobic

anxiety scores (

P

-values < 0.05).

Conclusions

The low-FODMAP diet may improve psychopathol-

ogy in IBS patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1419

EV435

EV435Life satisfaction and enjoyment

in medication-overuse headache

patients: The role of depression and

insomnia

M. Pompili

1 ,

, G. Paolo

2

, P. Martelletti

3

1

Rome, Italy

2

Sapienza, Department Nesmos, Roma, Italy

3

Sapienza, Department of Clinical and Molecular Medicine- Sapienza

University of Rome and Regional Referral Headache Centre-

Sant’Andrea Hospital–Rome–Italy, Roma, Italy

Corresponding author.

Introduction

Epidemiological research has documented a strong

association between medication-overuse headache (MOH)and

psychiatric disorders, emotional disturbances, and disordered per-

sonality traits, which are associated with worse outcomes, poorer

quality of life, and higher costs to the health care system.

Objectives

Identifying risk factors for progression of headache

into MOH represents one of the most relevant public health prior-

ities and psychiatric comorbidity has been identified as a potential

factor related to chronic phases.

Aims

The aim of the present study was to determine whether

depression and insomnia complaints were associated with satis-

faction and enjoyment with one’s own life in Medication-overuse

headache (MOH) patients, and whether insomnia complaints were

able to explain part of the variance of QoL explained by depression.

Methods

Participants were 187 consecutive adult outpatients

admitted to the outpatient headache clinic. Patients were adminis-

tered the Quality of Life Enjoyment and Satisfaction Questionnaire

(Q-LES-Q), the Beck Depression Inventory–II (BDI-II), and the

Athens Insomnia Scale (AIS).

Results

The BDI was associated with all the dimensions of the

Q-LES-Q, with more severe depression being associated indepen-

dently with lower satisfaction and enjoyment with one’s own life.

The AIS was independently and significantly associated only with

physical health, such that patients with more insomnia complaints

were 3.1 times (

P

< 0.001) more likely to report lower physical

health satisfaction.

Conclusions

Our findings confirmed that MOH has a negative

impact on quality of life, and suggested that depression and insom-

niawere independently associatedwith satisfaction and enjoyment

of life in MOH patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1420

EV436

Psychiatric comorbidity and suicide

risk in patients with psoriasis

M. Pompili

1 ,

, M. Innamorati

2

, D. Erbuto

3

, A. Costanzo

4

1

Rome, Italy

2

Università Europea di Roma, Department of Psychometrics, Roma,

Italy