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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S467

EV371

Study of sleep disturbances in patients

with alcohol abuse or dependence

M.D.C. García Mahía

, Á. Fernández Quintana

CHU A CORU ˜NA, Psychiatry, A Coru˜na, Spain

Corresponding author.

Introduction

Previous studies inform that psychiatric patients

often report problems with their sleep and alcohol increase sleep

disturbances.

Aims

To analyze the prevalence of sleep disturbances in patients

diagnosed of Alcohol Abuse or Dependence and to study clinical

and sociodemographic variables associated with sleep disorders.

Methods

The sample is composed of a randomized sample of

patients diagnosed of Alcohol Abuse or Dependence following

DSM-IV-TR criteria and treated in a Mental Health Clinic in a period

of 3 years. Medical records were reviewed. Quality and patterns of

sleep were evaluated using the Pittsburg Sleep Quality Index (PSQI)

with a cut-off point 5-6.

Results

A total of 102 patients were included in the study, 69%

were male and 31% were female. Mean age 39.4 years (SD 9.26).

Sleep disorders were found in 91.6% of patients. The most altered

subscales in the overall sample were the Use of Sleeping Medica-

tion and Sleep Disturbances. Women presentedworse sleep quality

compared to men (

P

< 0.01) with higher number of altered sub-

scales. The most altered subscales in women were Subjective Sleep

Quality (

P

< 0.005) and Sleep Disturbances (

P

< 0.02).

Comorbidity with other psychiatric disorders and other clinical and

sociodemographic variables are analyzed.

Conclusions

Sleep disorders have high prevalence in patients

with alcohol abuse of dependence, especially in women and

patients with other psychiatric comorbidity. Poor quality sleepmay

have a powerful impact on the global functioning and prognosis of

these groups of psychiatric patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1356

EV372

Dual pathology in users of early

intervention program in psychosis

B. Girela Serrano

1 ,

, M. Guerrero Jiménez

1

,

C.M. Carrillo de Albornoz Calahorro

1

, J.A. Rodrigo Manzano

2

,

O.B. Martínez García

1

1

Hospital Santa Ana Motril, Psiquiatría, Motril, Granada, Spain

2

Hospital Santa Ana Motril, Psicología, Motril, Granada, Spain

Corresponding author.

Introduction

The existence of independent services and facilities

for mental health and for addictions in Andalusia stand in the way

of addressing dual pathology. The strong comorbidity between sub-

stance use and early psychosis has been deeply studied in recent

literature. The aim of this paper is to analyse a group of consumers

in the First Episode Psychosis Program (FEP) to address the lack of

the actual interventions performed.

Methods

Descriptive statistical analysis of demographic and

clinical variables of a group with drug consumption (

n

= 17) is com-

pared to a non-consumer group (

n

= 7).

Results

Our sample of patients included, consumers who repre-

sent 71% of the sample. All consumers were users of cannabis or

derivatives and 35% of consumers were diagnosed at some point

of Toxic psychosis. Only 23% received care in drug addiction cen-

ters. They have less education. The duration of untreated psychosis

(DUP) is greater than in non-users and only 35% of the cases were

detected in Primary Care. PANSS with higher scores. Greater dif-

ferences in general psychopathology. The Social Functioning Scale

(SFS) were worse in the Isolation scale. The Family Questionnaire

(FQ) showed more difficulties in the family setting. Finally the

Global Assessment of Functioning (GAF) gives an average of 8 points

lower (severe symptoms).

Discussion

Wewould like to point out the lowpercentage of users

who receive specialized care for their addiction. Better collabo-

ration with Primary Care is required to improve the capacity of

detection to reduce the time slot of untreated symptoms.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1357

EV373

Psychiatric manifestations in

porphyria: A case report of psychosis

S. González-Parra

, T. Aparicio Reinoso , M. Leonor ,

J.D.D. Molina , I. Hernan , F. Ricote

Hospital Dr Rodríguez Lafora, Psychiatry, Madrid, Spain

Corresponding author.

Introduction

Porphyrias are rare inherited disorders due to spe-

cific enzyme abnormalities of heme biosynthesis. Among the

hepatic forms, three of them are clinically characterized by acute

abdominal pain and neuropathy, sometimes associated with psy-

chiatric disorders like mood changes, organic brain syndrome and

psychosis.

Case report

Here, we present a 38-year-old male patient with

intermittent porphyria and chronic psychosis who was hospital-

ized. He had been treated by benzodiacepines and neuroleptic

medication for several years. Exposure to certain drugs, dieting,

starvation and infection may precipitate AIP attacks.

Discussion

Underlying organic causes of psychiatric disorders

such as psychosis should be considered among patients with atyp-

ical symptoms and/or resistance to standard therapy.

Conclusion

It is important to increase awareness amongst psychi-

atric and neurological professionals with regard to certain inborn

errors of metabolism. Early detection of porphyria may diminish

morbidity andmortality rates, and perhaps heal some chronic atyp-

ical psychiatric illnesses.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1358

EV374

Cannabis psychosis, gender matters

I. Hamilton

, P. Galdas , H. Essex

University of York, Health Sciences, York, United Kingdom

Corresponding author.

Introduction

Despite recent findings pointing toward cannabis

psychosis as one area where gender differences may exist, there

has been a widespread lack of attention paid to gender as a deter-

minant of health in both psychiatric services and within the field

of addiction.

Objectives

To explore gender differences in treatment presenta-

tions for people with cannabis psychosis.

Aims

To use national data sets to investigate gender differences.

Methods

Analysis of British Crime Survey data and a Hospital

Episode Statistics data set were used in combinationwith data from

previously published epidemiological studies to compare gender

differences.

Results

Male cannabis users outnumber female users by 2:1,

a similar gender ratio is found for those admitted to hospital

with a diagnosis of schizophrenia or psychosis. However this ratio

increases significantly for those admitted to hospital with a diag-

nosis of cannabis psychosis, with males outnumbering females by

4:1.

Conclusions

This research brings into focus the marked gender

differences in cannabis psychosis. Attending to gender is important