European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S467
EV371
Study of sleep disturbances in patients
with alcohol abuse or dependence
M.D.C. García Mahía ∗, Á. Fernández Quintana
CHU A CORU ˜NA, Psychiatry, A Coru˜na, Spain
∗ Corresponding author.
Introduction Previous studies inform that psychiatric patients
often report problems with their sleep and alcohol increase sleep
disturbances.
Aims To analyze the prevalence of sleep disturbances in patients
diagnosed of Alcohol Abuse or Dependence and to study clinical
and sociodemographic variables associated with sleep disorders.
Methods The sample is composed of a randomized sample of
patients diagnosed of Alcohol Abuse or Dependence following
DSM-IV-TR criteria and treated in a Mental Health Clinic in a period
of 3 years. Medical records were reviewed. Quality and patterns of
sleep were evaluated using the Pittsburg Sleep Quality Index (PSQI)
with a cut-off point 5-6.
Results A total of 102 patients were included in the study, 69%
were male and 31% were female. Mean age 39.4 years (SD 9.26).
Sleep disorders were found in 91.6% of patients. The most altered
subscales in the overall sample were the Use of Sleeping Medica-
tion and Sleep Disturbances. Women presentedworse sleep quality
compared to men (P< 0.01) with higher number of altered sub-
scales. The most altered subscales in women were Subjective Sleep
Quality (P < 0.005) and Sleep Disturbances (P < 0.02).
Comorbidity with other psychiatric disorders and other clinical and
sociodemographic variables are analyzed.
Conclusions Sleep disorders have high prevalence in patients
with alcohol abuse of dependence, especially in women and
patients with other psychiatric comorbidity. Poor quality sleepmay
have a powerful impact on the global functioning and prognosis of
these groups of psychiatric patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV372
Dual pathology in users of early
intervention program in psychosis
B. Girela Serrano ∗, M. Guerrero Jiménez ,
C.M. Carrillo de Albornoz Calahorro , J.A. Rodrigo Manzano ,
O.B. Martínez García
1 Hospital Santa Ana Motril, Psiquiatría, Motril, Granada, Spain
2 Hospital Santa Ana Motril, Psicología, Motril, Granada, Spain
∗ Corresponding author.
Introduction The existence of independent services and facilities
for mental health and for addictions in Andalusia stand in the way
of addressing dual pathology. The strong comorbidity between sub-
stance use and early psychosis has been deeply studied in recent
literature. The aim of this paper is to analyse a group of consumers
in the First Episode Psychosis Program (FEP) to address the lack of
the actual interventions performed.
Methods Descriptive statistical analysis of demographic and
clinical variables of a group with drug consumption (n = 17) is com-
pared to a non-consumer group (n = 7).
Results Our sample of patients included, consumers who repre-
sent 71% of the sample. All consumers were users of cannabis or
derivatives and 35% of consumers were diagnosed at some point
of Toxic psychosis. Only 23% received care in drug addiction cen-
ters. They have less education. The duration of untreated psychosis
(DUP) is greater than in non-users and only 35% of the cases were
detected in Primary Care. PANSS with higher scores. Greater dif-
ferences in general psychopathology. The Social Functioning Scale
(SFS) were worse in the Isolation scale. The Family Questionnaire
(FQ) showed more difficulties in the family setting. Finally the
Global Assessment of Functioning (GAF) gives an average of 8 points
lower (severe symptoms).
Discussion Wewould like to point out the lowpercentage of users
who receive specialized care for their addiction. Better collabo-
ration with Primary Care is required to improve the capacity of
detection to reduce the time slot of untreated symptoms.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV373
Psychiatric manifestations in
porphyria: A case report of psychosis
S. González-Parra ∗, T. Aparicio Reinoso , M. Leonor ,
J.D.D. Molina , I. Hernan , F. Ricote
Hospital Dr Rodríguez Lafora, Psychiatry, Madrid, Spain
∗ Corresponding author.
Introduction Porphyrias are rare inherited disorders due to spe-
cific enzyme abnormalities of heme biosynthesis. Among the
hepatic forms, three of them are clinically characterized by acute
abdominal pain and neuropathy, sometimes associated with psy-
chiatric disorders like mood changes, organic brain syndrome and
psychosis.
Case report Here, we present a 38-year-old male patient with
intermittent porphyria and chronic psychosis who was hospital-
ized. He had been treated by benzodiacepines and neuroleptic
medication for several years. Exposure to certain drugs, dieting,
starvation and infection may precipitate AIP attacks.
Discussion Underlying organic causes of psychiatric disorders
such as psychosis should be considered among patients with atyp-
ical symptoms and/or resistance to standard therapy.
Conclusion It is important to increase awareness amongst psychi-
atric and neurological professionals with regard to certain inborn
errors of metabolism. Early detection of porphyria may diminish
morbidity andmortality rates, and perhaps heal some chronic atyp-
ical psychiatric illnesses.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV374
Cannabis psychosis, gender matters
I. Hamilton∗, P. Galdas , H. Essex
University of York, Health Sciences, York, United Kingdom
∗ Corresponding author.
Introduction Despite recent findings pointing toward cannabis
psychosis as one area where gender differences may exist, there
has been a widespread lack of attention paid to gender as a deter-
minant of health in both psychiatric services and within the field
of addiction.
Objectives To explore gender differences in treatment presenta-
tions for people with cannabis psychosis.
Aims To use national data sets to investigate gender differences.
Methods Analysis of British Crime Survey data and a Hospital
Episode Statistics data set were used in combinationwith data from
previously published epidemiological studies to compare gender
differences.
Results Male cannabis users outnumber female users by 2:1,
a similar gender ratio is found for those admitted to hospital
with a diagnosis of schizophrenia or psychosis. However this ratio
increases significantly for those admitted to hospital with a diag-
nosis of cannabis psychosis, with males outnumbering females by
4:1.
Conclusions This research brings into focus the marked gender
differences in cannabis psychosis. Attending to gender is important