European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S457
Background The method of “rehabilitation training”, developed
in the Soviet psychology, based on the idea that the human HMF are
realized in complex functional systems, developed during cultural-
and ontogenesis.
Aims To show the importance of the development of approaches
to the rehabilitation of HMF in Luria’s neuropsychology.
Methods The disturbances in brain activity leads to the neu-
ropsychological syndrome appearance that could be called
self-developing system. According to the systemic principles, each
neuropsychological syndrome HMF disorders in accordance with
brain injury localisation has the common “cause” – destroyed neu-
ropsychological factor. In the case of patientswith dementia several
neuropsychological factors are usually included. So the rehabilita-
tion processes should be aimed at the maximum preserved and
strengthened stereotypes and behavior strategies in past experi-
ences.
Results The binary syndrome structure (set of symptoms of
destroyed neuropsychological HMF and abnormal neuropsy-
chological factor itself) allows us to define two strategies of
neuropsychological rehabilitation programs. The first strategy
involves choice as a “target” of the most destroyedmental function.
The second strategy could be directed to the rehabilitation of abnor-
mal neuropsychological factor that should be accompanied by the
rehabilitation of several systemic interrelated mental functions.
Recourse to past knowledge, interests and emotionally important
topics is assisting and supporting the rehabilitation processes.
Conclusions Use of both strategies ensures targeted restoration
of cognitive functions within Vygotsky-Luria approach.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV341
The relationship between language
deficit, severity and structure of
cognitive decline and BPSD in patients
with dementia and MCI
M. Kralova ∗ eszaros Hideghety arkova
Z. Csefalvay , M. Hajduk
1 Medical Faculty Comenius University and University Hospital,
Psychiatric Clinic, Bratislava, Slovakia
2 Psychiatric Clinic University Hospital Comenius University,
Psychiatry, Bratislava, Slovakia
3 Department of communication disorders, Comenius University,
Logopaedic, Bratislava, Slovakia
∗ Corresponding author.
Introduction Comprehensive language testing shows a strong
relationship between overall severity of cognitive decline and lan-
guage deficit. Moreover, the language performance can be affected
also by neuropsychiatric symptoms of dementia.
Aim To detect the language deficits in sentence comprehension
in patients with MCI and dementia and to determine the relation-
ship between them, the severity and the structure of cognitive
impairment and independently between them and BPSD.
Method In the sample of 46 cognitively declined patients
(MCI and dementia, majority of them with Alzheimer’s dis-
ease), we evaluated the severity and the structure of cognitive
impairment by means of MoCA instrument, language deficits by
our own sentence comprehension test and BPSD by means of
NPI-Q.
Results The average performance in the sentence comprehension
testwas about 90%of normal in the group ofMCI patients, about 75%
in mild, about 60% in moderate and only about 20% in the group of
severe dementias. According to individual cognitive domains, their
impact on language performance was different. We found a strong
correlation between the overall severity of BPSD and the language
performance, too.
Conclusion At earlier stages of cognitive disorders/dementias, the
language specific test should be used to discover comprehension
deficits, because at the simple level of word the language skills are
preserved. BPSD are also associated with language deficits even
when the severity of dementia is controlled for. Identification of
these communication disturbances can help to detect cognitive
decline earlier and to start preserving treatment in time.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV342
Dementia due to HIV infection: Case
report
R. Almeida Leite ∗, C. Gama Pereira , E. Conde , T. Queirós Santos ,
M. Almeida , T. Azevedo Santos , A. Mesquita Figueiredo
Baixo Vouga Hospital Centre, Psychiatry and Mental Health
Department, Aveiro, Portugal
∗ Corresponding author.
Introduction The majority of HIV infected patients exhibit cen-
tral nervous system disorders. The most severe is dementia, which
is the most common cause of non-traumatic dementia in young
patients. It may affect the progression of the disease, compromising
the adherence of treatment and increasing the mortality rate.
Objectives Report of a clinical case of dementia due to HIV infec-
tion in a 33-year-old male patient, admitted in the Acute Inpatient
Unit of the Psychiatry and Mental Health Department in Baixo
Vouga Hospital Centre.
Methods The results were gathered based on the clinical history
of the patient, his objective exam, diagnostic exams and family
information and from medical research included on PubMed and
Google Scholar platforms.
Results The patient presented evident cognitive deterioration
with memory loss, attention and concentration deficits, apathy,
indifference, psychomotor retardation and behavioral changes in
the past few weeks, with a significant impact in his life. The
patient did supplementary diagnostic tests, which showed progres-
sivemultifocal leukoencephalopathy and global and diffuse cortical
atrophy involving the fronto-temporal regions and a neuropsycho-
logical assessment whose results confirmed a moderate cognitive
deficit. During the hospitalization there was a positive stabilization
of behavior with antiretroviral therapy and antipsychotics.
Conclusion The lack of knowledge about the factors that predis-
pose dementia in HIV patients is a relevant limitation nowadays.
The clinical effectiveness of antiretroviral therapy has improved in
recent years with a reduction in the prevalence of HIV dementia,
which now is estimated at 10%.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV343
Shared feelings: Investigating neural
attunement to the emotions of others
Y. Lerner ∗ endler Levit-Binnun olland
1 Tel Aviv Sourasky Medical Center & Tel Aviv University, Functional
Brain Center- Department of Neurology- Faculty of Medicine,
Tel-Aviv, Israel
2 Tel Aviv Sourasky Medical Center & Tel Aviv University, Functional
Brain Center- Faculty of Medicine- School of Psychological Science-
Sagol School of Neuroscience, Tel-Aviv, Israel
3 Interdisciplinary Center IDC, Sagol Center for Brain and Mind-
Baruch Ivcher School of Psychology, Herzliya, Israel
∗ Corresponding author.
Emotions of others can be highly contagious, affecting one’s own
emotional and neural responses. Yet, the neural mechanisms