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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S457

Background

The method of “rehabilitation training”, developed

in the Soviet psychology, based on the idea that the human HMF are

realized in complex functional systems, developed during cultural-

and ontogenesis.

Aims

To show the importance of the development of approaches

to the rehabilitation of HMF in Luria’s neuropsychology.

Methods

The disturbances in brain activity leads to the neu-

ropsychological syndrome appearance that could be called

self-developing system. According to the systemic principles, each

neuropsychological syndrome HMF disorders in accordance with

brain injury localisation has the common “cause” – destroyed neu-

ropsychological factor. In the case of patientswith dementia several

neuropsychological factors are usually included. So the rehabilita-

tion processes should be aimed at the maximum preserved and

strengthened stereotypes and behavior strategies in past experi-

ences.

Results

The binary syndrome structure (set of symptoms of

destroyed neuropsychological HMF and abnormal neuropsy-

chological factor itself) allows us to define two strategies of

neuropsychological rehabilitation programs. The first strategy

involves choice as a “target” of the most destroyedmental function.

The second strategy could be directed to the rehabilitation of abnor-

mal neuropsychological factor that should be accompanied by the

rehabilitation of several systemic interrelated mental functions.

Recourse to past knowledge, interests and emotionally important

topics is assisting and supporting the rehabilitation processes.

Conclusions

Use of both strategies ensures targeted restoration

of cognitive functions within Vygotsky-Luria approach.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1325

EV341

The relationship between language

deficit, severity and structure of

cognitive decline and BPSD in patients

with dementia and MCI

M. Kralova

1 ,

, B . M

eszaros Hideghety

2 , J. M

arkova

3 ,

Z. Csefalvay

3

, M. Hajduk

2

1

Medical Faculty Comenius University and University Hospital,

Psychiatric Clinic, Bratislava, Slovakia

2

Psychiatric Clinic University Hospital Comenius University,

Psychiatry, Bratislava, Slovakia

3

Department of communication disorders, Comenius University,

Logopaedic, Bratislava, Slovakia

Corresponding author.

Introduction

Comprehensive language testing shows a strong

relationship between overall severity of cognitive decline and lan-

guage deficit. Moreover, the language performance can be affected

also by neuropsychiatric symptoms of dementia.

Aim

To detect the language deficits in sentence comprehension

in patients with MCI and dementia and to determine the relation-

ship between them, the severity and the structure of cognitive

impairment and independently between them and BPSD.

Method

In the sample of 46 cognitively declined patients

(MCI and dementia, majority of them with Alzheimer’s dis-

ease), we evaluated the severity and the structure of cognitive

impairment by means of MoCA instrument, language deficits by

our own sentence comprehension test and BPSD by means of

NPI-Q.

Results

The average performance in the sentence comprehension

testwas about 90%of normal in the group ofMCI patients, about 75%

in mild, about 60% in moderate and only about 20% in the group of

severe dementias. According to individual cognitive domains, their

impact on language performance was different. We found a strong

correlation between the overall severity of BPSD and the language

performance, too.

Conclusion

At earlier stages of cognitive disorders/dementias, the

language specific test should be used to discover comprehension

deficits, because at the simple level of word the language skills are

preserved. BPSD are also associated with language deficits even

when the severity of dementia is controlled for. Identification of

these communication disturbances can help to detect cognitive

decline earlier and to start preserving treatment in time.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1326

EV342

Dementia due to HIV infection: Case

report

R. Almeida Leite

, C. Gama Pereira , E. Conde , T. Queirós Santos ,

M. Almeida , T. Azevedo Santos , A. Mesquita Figueiredo

Baixo Vouga Hospital Centre, Psychiatry and Mental Health

Department, Aveiro, Portugal

Corresponding author.

Introduction

The majority of HIV infected patients exhibit cen-

tral nervous system disorders. The most severe is dementia, which

is the most common cause of non-traumatic dementia in young

patients. It may affect the progression of the disease, compromising

the adherence of treatment and increasing the mortality rate.

Objectives

Report of a clinical case of dementia due to HIV infec-

tion in a 33-year-old male patient, admitted in the Acute Inpatient

Unit of the Psychiatry and Mental Health Department in Baixo

Vouga Hospital Centre.

Methods

The results were gathered based on the clinical history

of the patient, his objective exam, diagnostic exams and family

information and from medical research included on PubMed and

Google Scholar platforms.

Results

The patient presented evident cognitive deterioration

with memory loss, attention and concentration deficits, apathy,

indifference, psychomotor retardation and behavioral changes in

the past few weeks, with a significant impact in his life. The

patient did supplementary diagnostic tests, which showed progres-

sivemultifocal leukoencephalopathy and global and diffuse cortical

atrophy involving the fronto-temporal regions and a neuropsycho-

logical assessment whose results confirmed a moderate cognitive

deficit. During the hospitalization there was a positive stabilization

of behavior with antiretroviral therapy and antipsychotics.

Conclusion

The lack of knowledge about the factors that predis-

pose dementia in HIV patients is a relevant limitation nowadays.

The clinical effectiveness of antiretroviral therapy has improved in

recent years with a reduction in the prevalence of HIV dementia,

which now is estimated at 10%.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1327

EV343

Shared feelings: Investigating neural

attunement to the emotions of others

Y. Lerner

1 ,

, T . H

endler

2 , N.

Levit-Binnun

3 , Y. G

olland

3

1

Tel Aviv Sourasky Medical Center & Tel Aviv University, Functional

Brain Center- Department of Neurology- Faculty of Medicine,

Tel-Aviv, Israel

2

Tel Aviv Sourasky Medical Center & Tel Aviv University, Functional

Brain Center- Faculty of Medicine- School of Psychological Science-

Sagol School of Neuroscience, Tel-Aviv, Israel

3

Interdisciplinary Center IDC, Sagol Center for Brain and Mind-

Baruch Ivcher School of Psychology, Herzliya, Israel

Corresponding author.

Emotions of others can be highly contagious, affecting one’s own

emotional and neural responses. Yet, the neural mechanisms