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S406

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

when compared to the patients who did not discontinue medica-

tion. There were no other differences between the groups in the

clinical and demographical data. There was also no difference in

the level of adherence in patients treated by different drugs.

Conclusions

More thanhalf of bipolar patients discontinuedmed-

ication in the past. The risk of the discontinuation of medication is

higher in patients who are young and single. The rate of current

adherence significantly negatively correlated with self-stigma.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1160

EV176

Study of the impulsivity in bipolar

parent

G. Hamdi

1 ,

, M. karoui

2

, L. robbana

2

, F. elouze

2

, F. mrad

2

1

Razi Hospital, F, Mannouba, Tunisia

2

Razi Hospital, G, Mannouba, Tunisia

Corresponding author.

Introduction

Impulsivity, as defined by Barratt in 1983, is the

inability to associate a behavior to context or consequences. It refers

to a variety of risky behaviors, inappropriate to the situation and can

lead to undesirable consequences. It is well-established that impul-

sivity is strongly related to bipolar disorder. Currently, we speak

of impulsivity trait present even in bipolar patients in euthymia

given the hereditary nature of bipolar disorder. In this study, we are

interested in assessing impulsiveness in healthy relatives of bipolar

patients.

Methodology

Impulsivity was measured using BARRAT scale [the

Barratt impulsiveness Scale-11 (BIS-11)] in 30 healthy subjectswho

are first degree relatives of bipolar patients treated in Razi hospital;

and comparing the results to 30 subjects, witnessesmatched for age

and sex with no personal or family history of psychiatric disorders.

Results

The impulsivity score among parents of bipolar patients

was significantly higher compared to controls especially for motor

impulsivity with average scores 19.15 versus 16.94, respectively.

The general impulsivity score among parents of bipolar patients

was 61.53

±

13.83 versus an average score in controls of

47.20

±

18.26.

Limits

The small sample size did not allow conclusive results.

The difficulties in determining the mental history of the control

group (to check the absence of a family history of bipolar disorder).

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1161

EV177

The recognition of facial emotions in

bipolar disorder

G. Hamdi

, Dr. H. Ben Ammar , Z. Hechmi

Razi Hospital, F, Mannouba, Tunisia

Corresponding author.

Introduction

Bipolar disorder is a common chronic psychiatric

disorder, marked by the severity and frequency of mood episodes

and their impact on the psychosocial functioning of these patients.

Even during inter-critical periods, these patients’ cognitive func-

tions are altered. Patients diagnosed with bipolar disorder, by

definition, have problems with emotional regulation. However, it

remains uncertain whether these patients also have a deficit in

processing emotions of others.

The main objective was to assess social cognition (recognition of

facial emotions) in euthymic bipolar subjects by comparing them

to a control group.

Methodology

This is a transversal case-witness study, conducted

in consultation with the post-treatment, of 30 euthymic bipo-

lar patients and 30 healthy volunteers matched for age, sex and

educational level, with the help of a questionnaire targeting socio-

demographic and clinical data, as well as a facial expression

recognition test to measure social cognition.

Results

Our study showed that bipolar patients had deficits in

social cognition compared to the volunteers’ group. Bipolar patients

have more difficulties than healthy subjects to recognize facial

emotions of fear, anger and disgust, and assign intentions to others

from images. These deficits are even more accentuated in the early

onset forms.

Conclusion

This study shows a disturbance of perception of emo-

tions in bipolar patients. These cognitive deficits could participate

in behavioral and social disorders present in bipolar disorder.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1162

EV178

Childhood trauma in bipolar disorder

G. Hamdi

, H. Ben Ammar , Z. Hechmi

Razi Hospital, F, Mannouba, Tunisia

Corresponding author.

Introduction

Bipolar disorder is a multi-factorial disease and

has a heterogeneous clinical presentation. Currently, the negative

impact of stress on the evolutionary course of the disease is increas-

ingly being recognized. However, studies exploring the childhood

trauma in bipolar disorder are, so far, few and inconclusive.

Objectives

We sought to compare injury rates during childhood

in adults with bipolar disorder compared with a healthy control

group to study the impact of childhood trauma on the clinical evo-

lution of bipolar disorder.

Methods

A retrospective assessment of childhood trauma was

conducted using the Childhood Trauma Questionnaire (CTQ) with

30 patients with bipolar disorder who are stabilized and who fol-

lowing post treatment in the psychiatric unit “F” Razi hospital and

30 healthy subjects matched based on age and sex.

Results

Significantly higher rates of childhood trauma were

observed in bipolar patients compared to the control group. The

scores for sexual abuse and emotional neglect differ significantly

between the two groups. Psychological violence was predictive

of early onset bipolar disorder. Associations with clinical severity

were less clear.

Conclusion

Emotional deprivation in early childhood appears to

be significantly associated with bipolar disorder. More thorough

studies especially on the neurobiological consequences of child-

hood trauma would be necessary.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1163

EV179

Psychosocial functioning impairment

in euthymic patients with bipolar

disorder II: The role of clinical factors

R.S. Ilhan

1 ,

, V . S

enturk-Cankorur

2

1

Dr. Nafiz Korez Sincan State Hospital, Ministry of Health, Psychiatry,

Ankara, Turkey

2

Ankara University School of Medicine, Psychiatry, Ankara, Turkey

Corresponding author.

Introduction

Growing body of evidence have showed that

euthymic bipolar patients have poor psychosocial functioning.

Most of the studies have focused on the psychosocial functioning

in euthymic bipolar disorder (BD)-I patients. On the contrary, there

have been limited researches investigating psychosocial function-

ing in euthymic BD-II patients. Moreover, the factors associated

with psychosocial functioning in euthymic patients with BD II have

been also understudied.