European Psychiatry - Volume 33 - March 2016

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S406 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
when compared to the patients who did not discontinue medica-
tion. There were no other differences between the groups in the
clinical and demographical data. There was also no difference in
the level of adherence in patients treated by different drugs.
Conclusions More thanhalf of bipolar patients discontinuedmed-
ication in the past. The risk of the discontinuation of medication is
higher in patients who are young and single. The rate of current
adherence significantly negatively correlated with self-stigma.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV176
Study of the impulsivity in bipolar
parent
G. Hamdi ∗, M. karoui , L. robbana , F. elouze , F. mrad
1 Razi Hospital, F, Mannouba, Tunisia
2 Razi Hospital, G, Mannouba, Tunisia
∗ Corresponding author.
Introduction Impulsivity, as defined by Barratt in 1983, is the
inability to associate a behavior to context or consequences. It refers
to a variety of risky behaviors, inappropriate to the situation and can
lead to undesirable consequences. It is well-established that impul-
sivity is strongly related to bipolar disorder. Currently, we speak
of impulsivity trait present even in bipolar patients in euthymia
given the hereditary nature of bipolar disorder. In this study, we are
interested in assessing impulsiveness in healthy relatives of bipolar
patients.
Methodology Impulsivity was measured using BARRAT scale [the
Barratt impulsiveness Scale-11 (BIS-11)] in 30 healthy subjectswho
are first degree relatives of bipolar patients treated in Razi hospital;
and comparing the results to 30 subjects, witnessesmatched for age
and sex with no personal or family history of psychiatric disorders.
Results The impulsivity score among parents of bipolar patients
was significantly higher compared to controls especially for motor
impulsivity with average scores 19.15 versus 16.94, respectively.
The general impulsivity score among parents of bipolar patients
was 61.53 ±13.83 versus an average score in controls of
47.20 ±18.26.
Limits The small sample size did not allow conclusive results.
The difficulties in determining the mental history of the control
group (to check the absence of a family history of bipolar disorder).
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV177
The recognition of facial emotions in
bipolar disorder
G. Hamdi ∗, Dr. H. Ben Ammar , Z. Hechmi
Razi Hospital, F, Mannouba, Tunisia
∗ Corresponding author.
Introduction Bipolar disorder is a common chronic psychiatric
disorder, marked by the severity and frequency of mood episodes
and their impact on the psychosocial functioning of these patients.
Even during inter-critical periods, these patients’ cognitive func-
tions are altered. Patients diagnosed with bipolar disorder, by
definition, have problems with emotional regulation. However, it
remains uncertain whether these patients also have a deficit in
processing emotions of others.
The main objective was to assess social cognition (recognition of
facial emotions) in euthymic bipolar subjects by comparing them
to a control group.
Methodology This is a transversal case-witness study, conducted
in consultation with the post-treatment, of 30 euthymic bipo-
lar patients and 30 healthy volunteers matched for age, sex and
educational level, with the help of a questionnaire targeting socio-
demographic and clinical data, as well as a facial expression
recognition test to measure social cognition.
Results Our study showed that bipolar patients had deficits in
social cognition compared to the volunteers’ group. Bipolar patients
have more difficulties than healthy subjects to recognize facial
emotions of fear, anger and disgust, and assign intentions to others
from images. These deficits are even more accentuated in the early
onset forms.
Conclusion This study shows a disturbance of perception of emo-
tions in bipolar patients. These cognitive deficits could participate
in behavioral and social disorders present in bipolar disorder.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV178
Childhood trauma in bipolar disorder
G. Hamdi∗, H. Ben Ammar , Z. Hechmi
Razi Hospital, F, Mannouba, Tunisia
∗ Corresponding author.
Introduction Bipolar disorder is a multi-factorial disease and
has a heterogeneous clinical presentation. Currently, the negative
impact of stress on the evolutionary course of the disease is increas-
ingly being recognized. However, studies exploring the childhood
trauma in bipolar disorder are, so far, few and inconclusive.
Objectives We sought to compare injury rates during childhood
in adults with bipolar disorder compared with a healthy control
group to study the impact of childhood trauma on the clinical evo-
lution of bipolar disorder.
Methods A retrospective assessment of childhood trauma was
conducted using the Childhood Trauma Questionnaire (CTQ) with
30 patients with bipolar disorder who are stabilized and who fol-
lowing post treatment in the psychiatric unit “F” Razi hospital and
30 healthy subjects matched based on age and sex.
Results Significantly higher rates of childhood trauma were
observed in bipolar patients compared to the control group. The
scores for sexual abuse and emotional neglect differ significantly
between the two groups. Psychological violence was predictive
of early onset bipolar disorder. Associations with clinical severity
were less clear.
Conclusion Emotional deprivation in early childhood appears to
be significantly associated with bipolar disorder. More thorough
studies especially on the neurobiological consequences of child-
hood trauma would be necessary.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV179
Psychosocial functioning impairment
in euthymic patients with bipolar
disorder II: The role of clinical factors
R.S. Ilhan ∗ enturk-Cankorur
1 Dr. Nafiz Korez Sincan State Hospital, Ministry of Health, Psychiatry,
Ankara, Turkey
2 Ankara University School of Medicine, Psychiatry, Ankara, Turkey
∗ Corresponding author.
Introduction Growing body of evidence have showed that
euthymic bipolar patients have poor psychosocial functioning.
Most of the studies have focused on the psychosocial functioning
in euthymic bipolar disorder (BD)-I patients. On the contrary, there
have been limited researches investigating psychosocial function-
ing in euthymic BD-II patients. Moreover, the factors associated
with psychosocial functioning in euthymic patients with BD II have
been also understudied.