European Psychiatry - Volume 33 - March 2016

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S622 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Introduction For the most part, central nervous system (CNS)
tumors present themselves with focal neurologic sing or manifes-
tations resulting from increased intracranial pressure. However, in
particular cases, these tumors may present exclusively psychiatric
symptoms.
Objective This communication explores importance of CNS
tumors as differential diagnosis of various psychiatric disorders.
Aims Highlight the need of acknowledging this important differ-
ential diagnosis (CNS tumors) in current psychiatry practice, while
presenting a clinical case as an example of the subject.
Methods It is exposed a bibliographic review of the topic, fol-
lowed by the description of a clinical case regarding a patient
with pituitary adenoma and simultaneous installation of psychotic
symptoms namely delusional paranoid ideation.
Results The authors present a case report of a 66-year-old
patient admitted compulsively in a Psychiatric ward in the con-
text of behavioral changes associated with delusional ideation of
paranoid content. Multidisciplinary assessed by specialties of Psy-
chiatry, Neurology, Neurosurgery, Endocrinology and Psychology,
concluded by the presence of nonfunctioning pituitary adenoma
associated with cognitive major disturbance.
Conclusions The tumors of the CNS can be associated with a
whole variety of psychiatric symptoms such as psychosis, anxi-
ety, depression or cognitive impairment, even in the absence of
organic/neurological symptoms. Its role in the genesis of psy-
chiatric symptomatology makes these neoplasias an important
differential diagnosis, whose clinical approach should include dif-
ferent medical specialties integrated as a multidisciplinary team.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV853
Pancreatic cancer associated with
psychotic depression – A case report
M.E. Perfene-Banu ∗ . Cristache , I.A. Andrei , M.C. Tudorache ,
R.E. Popa , M. Manea
Psychiatry Clinical Hospital “Prof. Dr. Alexandru Obregia”, IV,
Bucuresti, Romania
∗ Corresponding author.
Pancreatic cancer is an aggressive form of cancer with increasing
incidence and a 5-year survival rate of 4% for all stages. Depression
and anxiety have a higher prevalence than the general popula-
tion in all cancer types. Also, rates of depression in patients with
pancreatic cancer are higher than in patients with other types of
gastrointestinal neoplasms. Depression in pancreatic cancer has
also been shown to impair quality of life, so early and adequate
antidepressant treatment is an essential component of comprehen-
sive supportive care.
We would like to report the case of a 67-year-old female patient,
with no previous psychiatric history, brought to the psychia-
try emergency unit by her husband for psycho-motor agitation,
persecutory delusions, delusional jealousy and bizarre behavior.
According to her husband, the symptoms started insidiously over
the last few weeks and that she attempted suicide by drug over-
dose three days before admission to our clinic, which she denies.
Three years prior to her hospitalization the patient received sur-
gical, radiotherapy and chemotherapy treatment for a base of
tongue tumor and 6months prior to her psychiatric admission, the
was diagnosed with cephalic pancreatic neoplasm for which she
received seven cycles of chemotherapy. Treatment with mirtaza-
pine, risperidone, and lorazepam was initiated. The evolution was
favorable and the patient was discharged one week later.
Early recognition and treatment of mood disorders associated with
cancer are important because, left untreated, theymay lead to diffi-
culty inmanaging symptoms, increased demand for health services
and low adherence to treatment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV854
Characterization of a referral to
psycho-oncology liaison consults in a
general hospital
J. Ramos ∗ liveira
Centro Hospitalar Tondela-Viseu, Psychiatry, Viseu, Portugal
∗ Corresponding author.
Introduction Liaison psychiatry is based on a practice that lies
on the interface between psychological, sociological and biological
factors of illness. Cancer is a devastating disease. For many patients
the occurrence of it is synonymous of chronic, severe or lethal
outcome. It is important for health professionals to be aware of
the psychological suffering of these patients and promote a proper
use of specialized consultations in order to increase and improve
adherence to treatment.
Aims To make known the reality of referral to a Psycho-Oncology
Liaison consult and its context in literature.
Methods Data collection on applications for the 1st request to
Psycho-Oncology liaison consults occurred between 2010–2012
in the variables, gender, age, reason for referral, psychiatric his-
tory, cancer diagnosis, knowledge of the referral and who does
(patient/family/service) and psychiatric diagnosis. Statistical anal-
ysis with Microsoft Excel 2010® .
Results It was found that there were 83 applications during the
three years, 24 men and 59 women. The most prevalent cancer
diagnoses were breast cancer (29.89%) and colorectal carcinoma
(19.28%). Most patients had knowledge of the request (75.9%). The
reason was mostly for Anxiety and Depression (33.73%).
Conclusion Cancer disease coupled with feelings of loss of auton-
omy, hopelessness and pain can lead the patient to develop
psychopathology of anxious-depressive disorders. This condition
may hamper the normal recovery of the patient. The promotion
of mental well-being in cancer patients is critical to recovery and
leads to a better adherence to treatment, inclusive can influence
survival.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV855
Cognitive decline induced by cerebral
radiotherapy: What to do?
T. Silva ∗, T. Carvalhão , M. Fernandes , J. Silva
Hospitalar and Universitary Center of Coimbra, Psychiatry, Coimbra,
Portugal
∗ Corresponding author.
Introduction Each year about 200 000 individuals undergo radio-
therapy treatment to primary brain cancer or brain metastasis. The
number of survivor has been rising with the improvement of treat-
ment and techniques. The current evidence suggest a progressive
cognitive decline in the years following brain irradiation, and show
that 50% of the people that survive longer than 6months are most
affected.
Aim The authors propose to make a literature review, trying to
expose the cognitive decline profile after cerebral brain therapy and
how to choose the best therapeutic option.
Methodology Literature review using the data base available in
the Documentation Service of the Central Library of the Centro
Hospitalar e Universitário de Coimbra.
Results and conclusions The severity profile of cognitive decline
influences the therapeutic options. The use of donepezile and