European Psychiatry - Volume 33 - March 2016

587 / 812

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S583
6 months ago she started with hematuria and urologist found a
multifocal oncocytoma in left kidney. Shewas operatedwithdouble
lumpectomy and partial nephrectomy without complications. Nor-
mal preoperative and postoperative renal function. Two months
ago, she started with dysarthria, dystonia and coarse tremor, and
T wave inversion on the electrocardiogram. In the blood test,
lythemia was 1.67mEQ/L. Creatinine was 0.65mg/dL. She was
admitted to Internal Medicine Unit. She was treated with rehydra-
tion by serum. All psychoactive drugs were removed. Twenty days
later, lithemia was undetectable in the blood analysis.
Results Twoweeks ago, the patient was transferred to themental
health unit due to worsening her mood. Lithium was reintroduced
3 days ago, at doses of 200mg per day. Today, the patient starts
again with symptoms of poisoning by lithium. Lithemia was 1.78.
Conclusions On this occasion, partial nephrectomy due to onco-
cytoma is themost likely cause two consecutive lithiumpoisonings.
Although creatinine and glomerular filtration are in normal range,
patients after partial nephrectomy may have a reduced sodium
reabsorption in proximal convoluted tubule, which may cause
lithium compensatory resorption. This could cause rising in blood
lithium levels.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV729
Delusional of parasitosis in geriatric
patients
M. Gutierrez Rodriguez ∗, C. Moreno Menguiano ,
F. Garcia Sanchez , R. Martin Aragon
Hospital Universitario de Móstoles, Psiquiatría, Móstoles, Spain
∗ Corresponding author.
Introduction Delusional of parasitosis or Ekbom’s syndrome (ES)
is a psychiatric disorder in which the patient has a fixed and
false belief that small organisms infest the body. The belief is
often accompanied by hallucinations. It is an uncommon condi-
tion that was initially studied by dermatologists, more prevalent
in the elderly and typically observed in women older than 50 years
although isolated cases among men have been reported.
Objective To review current knowledge about delusional of para-
sitosis in elderly patients through literature systematic review and
the analysis of a case report.
Methodology We performed a literature search using electronic
manuscripts available in PubMed database published during the
last five years, following the description and discussion of a clini-
cal case. We report a case of an 85-year-old man who presented a
delusional parasitosis as a primary disorder.
Results The literature on ES consists mostly of case reports and
limited series. In this paper, we analyze the etiology, demographic
characteristics, clinical features and treatment in geriatric patients
with delusional parasitosis.
Conclusion International classifications have included this syn-
drome in non-schizophrenic delusions. However, it has also been
reported in schizophrenia, affective disorders, and organic or
induced psychosis. Treatment is based on antipsychotic agents,
psychotherapy and cooperation between dermatologists and psy-
chiatrists.
Keywords Dermatozoic delusion; Ekbom syndrome;
Infestation; Parasitosis
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV730
To investigate quality of life in elderly
persons with dementia residing in
assisting living facility
Y.C. Hsu ∗, W.C. Ouyang , W.S. Huang
1 Chang Jung Christian University, Nursing, Tainan city, Taiwan
2 Lutung Christian Hospital and Changhua Christian Healthcare
System, Psychiatry, Changhua, Taiwan
3 Chang Jung Christian University, Health Care Administration,
Tainan City, Taiwan
∗ Corresponding author.
Introduction With constantly increasing aged populations, qual-
ity of life (QOL) in persons with dementia has become a significant
research concern. The Alzheimer’s Disease Related Quality of Life
(ADRQL) is a high-validated, theory-derived, andmultidimensional
instrument developed by Rabins et al. (1997, 2009) that has widely
utilized in many countries, except in Taiwan. However, diverse
results of quality of life from different countries by using the same
measurement can provide the potential to help understand the
impact of cultural contributor on QOL.
Objective To investigate the extent to which quality of life on
older adults with dementia in Taiwan.
Methods Cross-sectional, descriptive study conducted in an
assisting living facility affiliated with daycare center in southern
Taiwan. A purposeful sample of 34 participants was recruited.
Inclusion criteria: at least 65 years old, able to communicate, and
diagnosedwithmild tomoderate dementia. The QOLwasmeasured
by Chinese version ADRQL. This observational instrument consists
of 30 items that is divided to five subscales with the full range of
each subscale scores from 0 to 100.0. Higher scores indicate better
QOL.
Results The means for subscales of the Social Interaction, Aware-
ness of Self, Feelings and Mood, Enjoyment of Activities, and
Response to Surroundings were 87.9, 74.7, 91.3, 64.5, and 90.3,
respectively. The overall mean for the scale of ADQOL was 0.83.
Conclusion Findings suggest that the level of enjoyment of activ-
ities is the lowest and may convey information about a need of
evaluation on arrangement of facility’s activities.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV731
Comparative efficacy and safety of
antidepressive mono- and
multimodal therapy with citicoline in
elderly patients with depression in
psychogeriatric unit
Y. Kalyn ∗, S. Gavrilova , T. Safarova , E. Shipilova
Mental Health Research Center of the Russian Academy of Medical
Sciences, geriatricpsychiatry, Moscow, Russia
∗ Corresponding author.
Introduction Citicoline is a choline donor involved in the biosyn-
thesis of brain phospholipids and acetylcholine, used for treating
neurodegenerative disorders. Several studies have shown its ben-
eficial effects both in degenerative and vascular cognitive decline.
Due to its effects on the adrenergic and dopaminergic CNS activity,
citicoline can also be used as an adjuvant in depression treatment.
Objectives and aims Comparative evaluation of efficacy and safety
of a multimodal antidepressive therapy with ceraxone (citicoline)
plus one of the antidepressants (venlafaxine, agomelatine, or flu-
voxamine) and monotherapy with the same antidepressant for the
treatment of depression in the elderly. Two groups of patients were
included in the study (21 patients in each group) aged from 60 to
79 years old, comparable to the main clinical characteristics.