Table of Contents Table of Contents
Previous Page  590 / 812 Next Page
Information
Show Menu
Previous Page 590 / 812 Next Page
Page Background

S586

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

EV738

Depression in geriatric inpatients:

Correlations with nutritional state

and cognitive functions

I. Bonfitto

1

, G. Moniello

2

, L. Ariano

2

, M. Pascucci

1 ,

,

M.D. Zanasi

2

, A. Bellomo

1

1

University of Foggia, Institute of Psychiatry, Foggia, Italy

2

Ospedali Riuniti di Foggia, Department of Geriatric Medicine,

Foggia, Italy

Corresponding author.

Background

Although the prevalence of malnutrition is relatively

low among elderly people, the risk increases significantly among

inpatients and even more in those with mental deterioration.

Aims

To evaluate the possible association between the severity

of depressive symptoms, the nutritional status and the cognitive

decline in a sample of geriatric inpatients.

Methods

Fifty-one geriatric inpatients completed the following

tests:

– HamiltonDepression Rating Scale (HAM-D), to assess the severity

of depressive symptoms;

– Mini Nutritional Assessment (MNA), as a nutrition screening and

assessment tool;

– Mini Mental State Examination (MMSE), to assess the cognitive

impairment.

Results

There is a negative proportional relationship between

HAM-D and MMSE scores (

P

= 0.001) and between HAM-D and

MNA scores (

P

= 0.023). Depressed patients found to have a greater

cognitive impairment and a worse nutritional status. Considering

a HAM-D cut-off point of 14, distinguishing mild than moderate

depression, it shows a significant correlation with the MNA scores

(

P

= 0.008). Patients with HAM-D scores

14 have an average MNA

score of 19.8, while patients with HAM-D scores < 14 have an MNA

average score of 23.6. Euthymic or mildly depressed patients are

not at risk of malnutrition, while those with moderate or severe

depression have an increased risk of malnutrition.

Conclusions

Our study shows significant correlations between

the severity of depressive symptoms and the risk of malnutrition

or cognitive impairment. A mild depression state does not seem to

be associated with an increased risk of malnutrition.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1723

EV739

Neuropsychological and motivational

factors of cognitive efficiency in

elderly patients with essential arterial

hypertension

E. Pervichko

1 ,

, Y. Zinchenko

1

, O. Ostroumova

2

1

Lomonosov Moscow State University, Faculty of Psychology,

Moscow, Russia

2

Moscow State University of Medicine and Dentistry, Faculty of

General Medicine, Moscow, Russia

Corresponding author.

Introduction

The diagnostics of cognitive disorders (CD) in

patients with essential arterial hypertension (EAH) is often nec-

essary for the choice of treatment strategy.

Objective

To assess the role of neuropsychological and motiva-

tional factors in cognitive efficiency of elderly EAH patients.

Materials and methods

Twenty-five patients with EAH took part

in the study, stage 1–2, mean age was 67.6

±

6.1. The assessment

of cognitive functions embraced a quantitative measurement of

intelligence quotient (IQ) with the Wechsler Adult Intelligence

Scale (Wechsler, 1955), and investigation into qualitative features

of cognitive processes with Luria’s neuropsychological assessment

scheme (Luria, 1980) and Zeigarnik’s procedure of pathopsycho-

logical study (Zeigarnik, 1972).

Results

Within the psychological syndrome structure of CD in

EAH patients the leading part is played by the neuro-dynamic

factor, manifested in general lability, slowing down, and sud-

den exhaustion caused by reduction in energy of mental activity.

The conclusion is supported by the high frequency of described

symptoms among EAH patients and low dynamics of their reduc-

tion against the antihypertensive therapy (Pervichko et al., 2014,

2015). However, performance of experimental tasks makes 30% of

EAH patients reveal reduced motivation. They would achieve poor

results in general scoring, if compared with the group of highly

motivated participants. Correlation analysis data show the inter-

connection between frequency disturbances in motivation and

frequency in occurrence of various signs of cognitive decline, such

as low efficiency inmemorization and delayed recall, as well as low

IQ indices.

Conclusions

The data provide a strong argument to support the

hypothesis of particular importance of motivational factor of cog-

nitive efficiency in elderly EAH patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1724

EV740

Case-report and review of selective

serotonin reuptake

inhibitors-induced delirium in older

adults

S. Petrykiv

1 ,

, L. de Jonge

2

, M. Arts

3

1

GGZ Friesland, Psychiatric Emergency, Leeuwarden, Netherlands

2

UMC Groningen, Epidemiology, Groningen, Netherlands

3

UMC Groningen, Old Age Psychiatry, Groningen, Netherlands

Corresponding author.

Introduction

Selective serotonin reuptake inhibitors (SSRIs) are

the most widely prescribed antidepressants with generally fewer

side effects than most other types of antidepressants. However, in

frail elderly, the use of SSRIs was anecdotally reported as a potential

cause of a delirium.

Objectives

To present a case of citalopram-induced delirium in

an older adult diagnosed with late-life depression.

Aims

To review available literature on SSRI-induced delirium.

Methods

A case report is presented and discussed, followed by a

literature review.

Results

Seven published cases of SSRI-induced delirium in older

adults (> 60 years) were found while searching through Pubmed

and Embase. Our case of a 75-year-old female is also included in

this report. This patient was ambulatory treated with citalopram

20mg per os against depressive symptoms and she developed a

delirium four days after the initiation of the therapy. Blood tests

were normal and CT scan showed no significant findings. No other

medical evidence was found that could explain her delirium. Her

symptoms finally resolved after discontinuation of citalopram.

Conclusion

The on- and off-treatment side-effect correlation by

a segregate oral use of citalopram strongly suggests that SSRIs may

have the potential to cause a delirium, especially in frail elderly.

Further research on this topic is needed.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1725