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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

S307

EW544

Effectiveness of Brief Individual

Cognitive Behavioral Therapy for

auditory hallucinations in a sample of

Egyptian patients with schizophrenia

D. Nagui Rizk

1 ,

, H. Salama

1

, T. Molokhiya

1

, L. Kassem

2

1

Alexandria university, neuropsychiatry department, Alexandria,

Egypt

2

National Institute of Health, Department of health and human

services, Maryland, USA

Corresponding author.

E-mail address:

dalianagui82@hotmail.com

(D. Nagui Rizk)

Background

Auditory hallucination is one of the most common

symptoms in schizophrenia. The frequency of the auditory halluci-

nations and ensuing distress make the individual believe that these

voices are not able to be controlled and to be coped with.

Aim

Testing the effectiveness of brief cognitive behavioral ther-

apy for psychosis (CBTp) for auditory hallucinations, using it in

modifying the beliefs about the voices and improving symptom

severity and overall functioning.

Methods

Forty participantswith schizophreniawere randomized

into intervention and control groups. Intervention group were 20

patients who received 8 individual sessions of CBTp plus Treatment

As Usual (TAU) over 8 weeks and the control group were the other

20 patients who received TAU only. The Positive and Negative Syn-

drome Scale (PANSS), the Arabic version of Beliefs About Voices

Questionnaire (BAVQ) and the General Assessment of Functioning

scale (GAF) were assessed at baseline and at the end of the study.

Results

Intervention group showed a statistically significant

increase in GAF (

P

= 0.012), a statistically significant reduction

regarding the Positive (

P

< 0.001), Negative (

P

= 0.008), General

(

P

< 00.001) and total (

P

00.001) sub-scales of PANSS. Regarding

BAVQ, Intervention group showed a statistically significant reduc-

tion in Malevolence (

P

= 0.008), Engagement (

P

= 0.001); and

showed a statistically significant increase in Resistance (

P

= 0.049)

compared to control.

Conclusions

Brief cognitive behavioral therapy for auditory hallu-

cinations can improve severity of schizophrenia, increase the level

of functioning and improve the beliefs about the voices.

Keywords

Schizophrenia; Auditory hallucinations; Brief

cognitive behavioral therapy

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.662

EW545

The effect of a 16-week walking

program on biomarkers, physical

fitness, health related quality of life

and self-perceptions of adults with

schizophrenia

E. Oliveira

1 ,

, M. Uba-Chupel

2

, D. Sousa

3

, C. Rocha

4

,

A. Teixeira

2

, P. Ferreira

2

1

Sisters Hospitallers of the Sacred Heart of Jesus, Occupational

Therapy - Casa Saúde Rainha Santa Isabel, Coimbra, Portugal

2

Faculty of Sport Sciences and Physical Education- University of

Coimbra, Research Unit for Sport and Physical Activity, Coimbra,

Portugal

3

Sisters Hospitallers of the Sacred Heart of Jesus, Nurse - Casa Saúde

Rainha Santa Isabel, Coimbra, Portugal

4

Polytechnic Institute of Coimbra- ESTESC - Coimbra Health School,

Department Complementary Sciences- INESCC, Coimbra, Portugal

Corresponding author.

Introduction

People with schizophrenia exhibit low levels of

physical activity, which have impact on physical and mental health

as well as overall quality of life (QOL). Mental and physical benefits

of exercise are known, although the mechanisms through which

physical exercise improves schizophrenia symptoms are not fully

understood.

Objectives

To assess the effect of a 16-week exercise program

(EP) on the expression of BDNF and S100B biomarkers, physical

fitness, health related quality of life and self-perceptions of adults

with schizophrenia.

Methods

Thirty-five patients with schizophrenia (PwSZ) were

divided in three groups Institutionalized Patients (

n

= 11); Psy-

chosocial Rehabilitation (

n

= 13); and Control Group (

n

= 11). The

EP consisted of one-hour walking session three times a week dur-

ing 16 weeks. All participants were assessed before and after EP

using the six minutes walking test, a psychological tests battery

including MOS Short Form 36, Rosenberg Self-Esteem Scale, Physi-

cal Self-Perception Profile, Satisfaction with Life Scale as well as the

BDNF and S100B measurements using serum analysis.

Results

No significant statistical differences were found both for

BDNF and S100B levels as a result of exercise. Additionally, no sig-

nificant statistical differences were found for Physical Self-concept

and Global Self-esteem changes as a result of the walking program

(WP). However, PwSZ showed significant statistical differences on

the satisfaction with life (

P

< 0.05) and on the perceived health

related QOL (

P

< 0.05) in all groups participating in the EP.

Conclusion

In spite of the limited impact of the WP in PwSZ, this

group may obtain positive outcomes of the exercise participation

based on a more positive attitude towards life.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.663

EW546

Social cognition across stages and

forms of schizophrenia

O. Papsuev

, M.

Minyaycheva , L. Movina , I. Gurovich

Moscow Research Institute of Psychiatry, Outpatient Psychiatry and

Organization of Psychiatric Care, Moscow, Russia

Corresponding author.

Introduction

Social cognition is considered as a main predic-

tor of functional outcomes and a candidate for endophenotype

of schizophrenia. We hypothesize that social cognition capacities

follow the course of schizophrenia as a progredient disorder.

Objective

To investigate social cognition across different groups

of patients with schizophrenia and schizophrenia spectrum disor-

ders.

Aims

To evaluate social cognitive impairments in patients with

first episode psychoses (FEP), chronic schizophrenia (CS) and

schizophrenia-spectrum disorders (SSD).

Methods

In a cross-sectional study, 71 patients with FEP, CS and

SSD were assessed with a battery of clinical and social cognitive

tests. Three key social cognitive domains were assessed: emotion

perception, Theory of Mind and attributional style.

Results

Patients with schizoaffective disorder and schizotypal

disorder showed better scores in Hinting task (mean ranks:

47.0 and 39.9 respectively) than patients with less favourable

forms of schizophrenia (mean ranks: 24.7 and 30.2 respectively)

(

P

= 0.003). Patients with FEP showed better results in Hinting

task (18.1

±

2.4) versus CS patients (17.4

±

2.0) (

P

< 0.05). No dif-

ferences in emotion perception (Ekman-60 task) among FEP and

CS patients were detected. Patients with schizoaffective disorder

showed better scores in emotional processing comparing to all

forms of schizophrenia patients (mean ranks 49.1 vs. 30.1, 34.5,

28.0,

P

< 0.05). No significant differences in attributional style were

registered.

Conclusions

Emotion perception and Theory of Mind domains

show different level of impairment across FEP and CS patients

and across forms of schizophrenia. Further longitudinal studies