European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348 S307
EW544
Effectiveness of Brief Individual
Cognitive Behavioral Therapy for
auditory hallucinations in a sample of
Egyptian patients with schizophrenia
D. Nagui Rizk ∗, H. Salama , T. Molokhiya , L. Kassem
1 Alexandria university, neuropsychiatry department, Alexandria,
Egypt
2 National Institute of Health, Department of health and human
services, Maryland, USA
∗ Corresponding author.
E-mail address: (D. Nagui Rizk)
Background Auditory hallucination is one of the most common
symptoms in schizophrenia. The frequency of the auditory halluci-
nations and ensuing distress make the individual believe that these
voices are not able to be controlled and to be coped with.
Aim Testing the effectiveness of brief cognitive behavioral ther-
apy for psychosis (CBTp) for auditory hallucinations, using it in
modifying the beliefs about the voices and improving symptom
severity and overall functioning.
Methods Forty participantswith schizophreniawere randomized
into intervention and control groups. Intervention group were 20
patients who received 8 individual sessions of CBTp plus Treatment
As Usual (TAU) over 8 weeks and the control group were the other
20 patients who received TAU only. The Positive and Negative Syn-
drome Scale (PANSS), the Arabic version of Beliefs About Voices
Questionnaire (BAVQ) and the General Assessment of Functioning
scale (GAF) were assessed at baseline and at the end of the study.
Results Intervention group showed a statistically significant
increase in GAF (P = 0.012), a statistically significant reduction
regarding the Positive (P < 0.001), Negative (P = 0.008), General
(P < 00.001) and total (P ≤ 00.001) sub-scales of PANSS. Regarding
BAVQ, Intervention group showed a statistically significant reduc-
tion in Malevolence (P = 0.008), Engagement (P = 0.001); and
showed a statistically significant increase in Resistance (P = 0.049)
compared to control.
Conclusions Brief cognitive behavioral therapy for auditory hallu-
cinations can improve severity of schizophrenia, increase the level
of functioning and improve the beliefs about the voices.
Keywords Schizophrenia; Auditory hallucinations; Brief
cognitive behavioral therapy
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW545
The effect of a 16-week walking
program on biomarkers, physical
fitness, health related quality of life
and self-perceptions of adults with
schizophrenia
E. Oliveira ∗, M. Uba-Chupel , D. Sousa , C. Rocha ,
A. Teixeira , P. Ferreira
1 Sisters Hospitallers of the Sacred Heart of Jesus, Occupational
Therapy - Casa Saúde Rainha Santa Isabel, Coimbra, Portugal
2 Faculty of Sport Sciences and Physical Education- University of
Coimbra, Research Unit for Sport and Physical Activity, Coimbra,
Portugal
3 Sisters Hospitallers of the Sacred Heart of Jesus, Nurse - Casa Saúde
Rainha Santa Isabel, Coimbra, Portugal
4 Polytechnic Institute of Coimbra- ESTESC - Coimbra Health School,
Department Complementary Sciences- INESCC, Coimbra, Portugal
∗ Corresponding author.
Introduction People with schizophrenia exhibit low levels of
physical activity, which have impact on physical and mental health
as well as overall quality of life (QOL). Mental and physical benefits
of exercise are known, although the mechanisms through which
physical exercise improves schizophrenia symptoms are not fully
understood.
Objectives To assess the effect of a 16-week exercise program
(EP) on the expression of BDNF and S100B biomarkers, physical
fitness, health related quality of life and self-perceptions of adults
with schizophrenia.
Methods Thirty-five patients with schizophrenia (PwSZ) were
divided in three groups Institutionalized Patients (n = 11); Psy-
chosocial Rehabilitation (n = 13); and Control Group (n = 11). The
EP consisted of one-hour walking session three times a week dur-
ing 16 weeks. All participants were assessed before and after EP
using the six minutes walking test, a psychological tests battery
including MOS Short Form 36, Rosenberg Self-Esteem Scale, Physi-
cal Self-Perception Profile, Satisfaction with Life Scale as well as the
BDNF and S100B measurements using serum analysis.
Results No significant statistical differences were found both for
BDNF and S100B levels as a result of exercise. Additionally, no sig-
nificant statistical differences were found for Physical Self-concept
and Global Self-esteem changes as a result of the walking program
(WP). However, PwSZ showed significant statistical differences on
the satisfaction with life (P < 0.05) and on the perceived health
related QOL (P < 0.05) in all groups participating in the EP.
Conclusion In spite of the limited impact of the WP in PwSZ, this
group may obtain positive outcomes of the exercise participation
based on a more positive attitude towards life.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW546
Social cognition across stages and
forms of schizophrenia
O. Papsuev∗ Minyaycheva , L. Movina , I. Gurovich
Moscow Research Institute of Psychiatry, Outpatient Psychiatry and
Organization of Psychiatric Care, Moscow, Russia
∗ Corresponding author.
Introduction Social cognition is considered as a main predic-
tor of functional outcomes and a candidate for endophenotype
of schizophrenia. We hypothesize that social cognition capacities
follow the course of schizophrenia as a progredient disorder.
Objective To investigate social cognition across different groups
of patients with schizophrenia and schizophrenia spectrum disor-
ders.
Aims To evaluate social cognitive impairments in patients with
first episode psychoses (FEP), chronic schizophrenia (CS) and
schizophrenia-spectrum disorders (SSD).
Methods In a cross-sectional study, 71 patients with FEP, CS and
SSD were assessed with a battery of clinical and social cognitive
tests. Three key social cognitive domains were assessed: emotion
perception, Theory of Mind and attributional style.
Results Patients with schizoaffective disorder and schizotypal
disorder showed better scores in Hinting task (mean ranks:
47.0 and 39.9 respectively) than patients with less favourable
forms of schizophrenia (mean ranks: 24.7 and 30.2 respectively)
(P = 0.003). Patients with FEP showed better results in Hinting
task (18.1± 2.4) versus CS patients (17.4 ± 2.0) (P < 0.05). No dif-
ferences in emotion perception (Ekman-60 task) among FEP and
CS patients were detected. Patients with schizoaffective disorder
showed better scores in emotional processing comparing to all
forms of schizophrenia patients (mean ranks 49.1 vs. 30.1, 34.5,
28.0, P < 0.05). No significant differences in attributional style were
registered.
Conclusions Emotion perception and Theory of Mind domains
show different level of impairment across FEP and CS patients
and across forms of schizophrenia. Further longitudinal studies