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S136

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

3

Clinical Hospital of Psychiatry “Al. Obregia”, 9 Ward, Bucharest,

Romania

4

Clinical Hospital of Psychiatry “Elisabeta Doamna”, Psychiatry,

Galati, Romania

5

Emergency County Hospital Cluj-Napoca- Romania, Second

Psychiatric Clinic, Cluj-Napoca, Romania

Corresponding author.

Introduction

Bipolar patients show broad cognitive deficits and

low global functioning.

Objective

Assessment of global functioning in bipolars with

severe course of illness and cognitive deficits.

Aim

Improving life quality of bipolar patients with cognitive

deficits.

Methods

One hundred and thirty-seven bipolar (depressive:

Hamilton Depression Rating Scale score

17, manic/hypomanic:

Young Mania Rating Scale score

12, mixed: HAMD score > 8 and

YMRS score > 6, euthymic: 6-month of remission, HAMD score

8,

YMRS score

6) patients (DSMIVTR). Cognitive battery included

standardized test of IQ, attention, executive functioning, memory

(working and verbal). GAF (Global Assessment Functioning Scale)

scale assessed global functionality. Demographic data, psychiatric

history, past/current treatment, length of illness, age of onset were

collected. We evaluate global functioning in bipolar patients.

Results

Cognitive deficits with low functioning are more fre-

quent in bipolars with more severe course of illness (longer illness

length, younger onset age, history of frequent manic episodes,

higher number of hospitalization). Manic patients showed themost

pronounced cognitive deficits. Despite high energy, impaired cog-

nitive function does not support performance and final result is

an important decrease of functionality. While for most manic and

mixed patients, GAF scores were included between 41 and 50

(any serious deterioration in socio-occupational, school function-

ing), for majority of depressive patients, GAF scores were included

between 51 and 60 (moderate difficulty in socio-occupational,

school functioning) and for most euthymic patients, the GAF scores

were comprised between 61 and 70 (some difficulty in socio-

occupational, school functioning). Manic and mixed patients have

similar employment percentages (< 50%), and lowest employment

percentage is obtained by depressive ones (40%).

Conclusions

Severe course of bipolar disorder is associated with

cognitive deficits and lower socio-occupational functionality.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.176

Child and adolescent psychiatry

EW59

Correlation of vitamin D to attention

deficit hyperactivty disorder

M. Abouzed

, A. Moshref , A. Elsherbiny , M. Elsheikh

Al-Azhar Faculty of Medicine, Psychiatry, Cairo, Egypt

Corresponding author.

ADHD is one of the most common neurodevlopmental psychiatric

disorders. Many factors have been identified as the cause of ADHD.

ADHD is thought to be the result of interactions between biopsy-

chosocial factors leading to neurobiliogcal change. The aim of this

study is to investigate the association between serum level of vita-

min D and symptoms of attention deficit hyperactivity disorder

(ADHD).

Design

This is a case-control study which was conducted in

children below 12 years of age from June 2013 to May 2014 at

outpatient child psychiatry clinic at ElhussinHospital Al-Azhar Uni-

versity, Cairo, Egypt.

Methods and subjects

The study was based on 62 cases and

30 controls. The data collection instrument included socio-

demographic & Children Attention and Adjustment Survey (House

form)

{

CAAS

}

. And interview by (Diagnostic Interview Kiddie-

Sads-Present and Lifetime Version (K-SADS-PL) to exclude other

psychiatric morbidity. clinical data, serum 25(OH) Vitamin D.

Descriptive statistical analysis were performed, Pearson Chi

2

test

(

2

) and Student (

t

) test.

Result

1-Vitamin D level was much lower in ADHD children com-

pared to healthy children, and was a significant difference in the

mean values of vitamin D between ADHD(23

±

13) and control

group means (44

±

12) and

P

value was > 0.001 and was signifi-

cant difference between subgroup of ADHD, means of inattentive

subtypewas(20

±

13) hyper active subtype (30.1

±

5)and combined

subtype(24.04

±

4).

P

value 0.011

*

.

Conclusion

Children with ADHD had significantly lower levels of

VITAMIN D than healthy, and inattention subtype than other types

of ADHD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.177

EW60

Prevalence rate of psychiatric

disorders among Saudi Female

adolescents: School-based study from

Riyadh City

Y. Alatiq

, O. Al-Modayfer

King Abdulaziz Medical City, Medicine, Riyadh, Kingdom of Saudi

Arabia

Corresponding author.

Introduction

Studies have shown that mental health problems at

an early age can lead to greater impairment in adult life. Epidemio-

logical evidence on the prevalence and incidence of mental health

disorders is fundamental for planningmental health services. How-

ever, these data are lacking in Saudi Arabia.

Objectives

The objective of the study is to examine the prevalence

of mental health problems in Saudi female adolescents attending

high school in Riyadh City.

Aims

The primary aim is to examine the prevalence rate of

psychiatric disorders. Second is to examine some psychosocial vari-

ables as predictors of psychiatric disorders.

Methods

This two-stage epidemiological study used the

Strengths and Difficulties Questionnaire (SDQ) to screen all

eligible participants for the presence of a possible psychiatric

disorder. The screening was followed by the use of a structured

psychiatric interview (MINI-Kid), which was administered to a

sub-sample to confirm the presence or absence of psychiatric

disorders.

Results

A total of 4745 participants were screened in the first

stage, and 692 participants underwent follow-up interviews. Ago-

raphobia was the most common disorder with a prevalence rate of

(30.6%), followed by major depressive episode (29.9%), then sepa-

ration anxiety disorder (27.1%). The only variables with a predictive

power of having a psychiatric disorder were “having a private

teacher” (OR = 1.86, 95% CI (1.13–3/07),

P

= 0.013).

Conclusion

The rate of psychiatric disorders among Saudi female

adolescents is within the wide range reported internationally but

is associated with specific social predictive factors.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.178