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S142

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

EW76

Deficit in executive abilities as a risk

factor for emerging weakness in

grammar understanding in

Russian-speaking children

S. Kiselev

Ural Federal University, Clinical Psychology, Ekaterinburg, Russia

Introduction

Weakness in grammar understanding is key future

of specific language impairment (SLI) in children. There has been a

considerable amount of work on the language abilities of children

with SLI, but we still know relatively little about their other cogni-

tive abilities –in particular their non-linguistic cognitive strengths

and weaknesses.

Aims

The aimof this researchwas to examine the hypothesis that

Russian-speaking children at the age of 4 with deficit in executive

abilities have a risk for emerging weakness in grammar under-

standing at the age of 6.

Methods

One hundred and twenty-five children at the age of 4

were assessedwith theNEPSY to reveal childrenwith different level

of executive abilities. We have revealed 21 children with deficit in

executive abilities. The control group included 21 children with

typical level of executive abilities. The children from experimental

and control group were matched for IQ and gender. In the frame-

work of longitudinal research, children at the age of 6 from both

groups were assessed by Grammar Understanding Test fromLuria’s

neuropsychological assessment technique.

Results

Two-way ANOVAs with repeated measures revealed sig-

nificant differences between groups for scores in the Grammar

Understanding Test. Children from experimental group had weak-

ness in grammar understanding.

Conclusions

We have revealed that children at the age of 4 with

weakness in executive abilities have a risk for emerging weakness

in grammar understanding at the age of 6. In view of the obtained

results, it can be assumed that executive abilities have influence on

the development of grammar understanding in preschool children.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.194

EW77

Neurocognitive deficits underlying

attention-deficit/hyperactivity

disorder (ADHD): A

clustering/subgrouping analysis

P. Leung

, F. Chan

The Chinese University of Hong Kong, Psychology, Shatin, Hong Kong,

China

Corresponding author.

Introduction

Neurocognitive deficits are assumed to be underly-

ing the behavioral symptoms of ADHD. Research over the years has

identified a host of these neurocognitive deficits, but no single one

deficit appears to be dominant or pervasive in all ADHD children.

This raises the query whether there can be further subgrouping of

ADHD children at the neurocognitive level.

Objectives and aims

This study aims at disentangling the het-

erogeneous neurocognitive deficits underlying ADHD. To achieve

this, we explore if there are separable neurocognitive subgroups in

ADHD children.

Methods

One hundred and sixty-four Chinese ADHD boys and

163 typically developing controls, aged 6 to 12, were recruited in

Hong Kong. A neurocognitive battery of executive function (EF)

measures was administered. Cluster analysis was first conducted

to identify subgroups of ADHD children based on their neurocogni-

tive functioning. MANOVA was then employed to further explore

the differences between subgroups.

Results

Two ADHD subgroups were identified. One subgroup

showed multiple EF deficits, including disinhibition, impaired

interference control, distorted temporal information processing,

slow processing speed, and delay aversion. The other subgroup, on

the contrary, had intact EF but increased response variability. Both

subgroups had comparable ADHD phenotypic severity and comor-

bidity pattern. However, ADHD children in the EF deficits subgroup

were more responsive to medication (i.e., methylphenidate).

Conclusion

Results support the neurocognitive heterogeneity of

ADHD. EF deficits and response variability are two separable

neurocognitive profiles underlying and subgrouping ADHD chil-

dren of comparable severity. This subgrouping has implication for

medication response and offers candidate endophenotypes for neu-

roimaging and genetic study.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.195

EW78

Do children with autism spectrum

disorder have impaired sleep

patterns?

A. Memari

, S. Hafizi

Tehran University of medical science, sport-medicine, Tehran, Iran

Corresponding author.

Introduction

Literature has emerged to offer contradictory find-

ings about sleep disturbances in autistic population and there

is still insufficient data for the background and associations of

sleep problems (e.g. demographic variables, severity of autism and

comorbidities) in autism research and little attention has been paid

to autism specific factors.

Objectives

This study seeks to add further evidence on sleep pat-

terns specific to autistic children and help answer some of the

questions in this field in a population with a different culture (Mid-

dle East).

Methods

Eighty-six children and adolescents with autism were

enrolled. Parents were asked to provide medication history and

other comorbidities. Behavior problems were assessed via autism

treatment evaluation checklist. Sleep diary forms was completed

by parents to record children nocturnal sleep over a 7-day period

and in times in which Actigraphy

TM

were taken off. Moreover, we

used GT3X monitor Actigraph

TM

to assess sleep problems.

Results

The

T

-test analysis for sleep minuets revealed that

females had slept marginally more minutes than males (

P

= 0.05).

T

-test analysis showed no significant difference in sleep parame-

ters between those using and not using any psychotropic agents.

Comorbidities analysis showed that children with comorbid con-

ditions slept more (

P

= 0.01), went to bed later (

P

= 0.03) and had

more number of awakening (

P

< 0.001) than participants without

comorbid conditions. Sleep minuets were correlated with deficit

in sensory cognitive awareness (

r

= 0.236,

P

= 0.035). Behavioural

deficit and number of awakening (

r

= 0.246,

P

= 0.028) were corre-

lated significantly.

Conclusion

Our overall findings showed the association of sleep

problems and behavioral deficit and comorbidities in autism.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.196

EW79

Role of music and non-musical

techniques in self-guided emotional

regulation

R. Mohan

, N. Anand

Surrey and Borders Partnership NHS Foundation Trust, Child and

Adolescent Psychiatry, Guildford, United Kingdom