European Psychiatry - Volume 33 - March 2016

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S142 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348
EW76
Deficit in executive abilities as a risk
factor for emerging weakness in
grammar understanding in
Russian-speaking children
S. Kiselev
Ural Federal University, Clinical Psychology, Ekaterinburg, Russia
Introduction Weakness in grammar understanding is key future
of specific language impairment (SLI) in children. There has been a
considerable amount of work on the language abilities of children
with SLI, but we still know relatively little about their other cogni-
tive abilities –in particular their non-linguistic cognitive strengths
and weaknesses.
Aims The aimof this researchwas to examine the hypothesis that
Russian-speaking children at the age of 4 with deficit in executive
abilities have a risk for emerging weakness in grammar under-
standing at the age of 6.
Methods One hundred and twenty-five children at the age of 4
were assessedwith theNEPSY to reveal childrenwith different level
of executive abilities. We have revealed 21 children with deficit in
executive abilities. The control group included 21 children with
typical level of executive abilities. The children from experimental
and control group were matched for IQ and gender. In the frame-
work of longitudinal research, children at the age of 6 from both
groups were assessed by Grammar Understanding Test fromLuria’s
neuropsychological assessment technique.
Results Two-way ANOVAs with repeated measures revealed sig-
nificant differences between groups for scores in the Grammar
Understanding Test. Children from experimental group had weak-
ness in grammar understanding.
Conclusions We have revealed that children at the age of 4 with
weakness in executive abilities have a risk for emerging weakness
in grammar understanding at the age of 6. In view of the obtained
results, it can be assumed that executive abilities have influence on
the development of grammar understanding in preschool children.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW77
Neurocognitive deficits underlying
attention-deficit/hyperactivity
disorder (ADHD): A
clustering/subgrouping analysis
P. Leung ∗, F. Chan
The Chinese University of Hong Kong, Psychology, Shatin, Hong Kong,
China
∗ Corresponding author.
Introduction Neurocognitive deficits are assumed to be underly-
ing the behavioral symptoms of ADHD. Research over the years has
identified a host of these neurocognitive deficits, but no single one
deficit appears to be dominant or pervasive in all ADHD children.
This raises the query whether there can be further subgrouping of
ADHD children at the neurocognitive level.
Objectives and aims This study aims at disentangling the het-
erogeneous neurocognitive deficits underlying ADHD. To achieve
this, we explore if there are separable neurocognitive subgroups in
ADHD children.
Methods One hundred and sixty-four Chinese ADHD boys and
163 typically developing controls, aged 6 to 12, were recruited in
Hong Kong. A neurocognitive battery of executive function (EF)
measures was administered. Cluster analysis was first conducted
to identify subgroups of ADHD children based on their neurocogni-
tive functioning. MANOVA was then employed to further explore
the differences between subgroups.
Results Two ADHD subgroups were identified. One subgroup
showed multiple EF deficits, including disinhibition, impaired
interference control, distorted temporal information processing,
slow processing speed, and delay aversion. The other subgroup, on
the contrary, had intact EF but increased response variability. Both
subgroups had comparable ADHD phenotypic severity and comor-
bidity pattern. However, ADHD children in the EF deficits subgroup
were more responsive to medication (i.e., methylphenidate).
Conclusion Results support the neurocognitive heterogeneity of
ADHD. EF deficits and response variability are two separable
neurocognitive profiles underlying and subgrouping ADHD chil-
dren of comparable severity. This subgrouping has implication for
medication response and offers candidate endophenotypes for neu-
roimaging and genetic study.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW78
Do children with autism spectrum
disorder have impaired sleep
patterns?
A. Memari∗, S. Hafizi
Tehran University of medical science, sport-medicine, Tehran, Iran
∗ Corresponding author.
Introduction Literature has emerged to offer contradictory find-
ings about sleep disturbances in autistic population and there
is still insufficient data for the background and associations of
sleep problems (e.g. demographic variables, severity of autism and
comorbidities) in autism research and little attention has been paid
to autism specific factors.
Objectives This study seeks to add further evidence on sleep pat-
terns specific to autistic children and help answer some of the
questions in this field in a population with a different culture (Mid-
dle East).
Methods Eighty-six children and adolescents with autism were
enrolled. Parents were asked to provide medication history and
other comorbidities. Behavior problems were assessed via autism
treatment evaluation checklist. Sleep diary forms was completed
by parents to record children nocturnal sleep over a 7-day period
and in times in which ActigraphyTM were taken off. Moreover, we
used GT3X monitor ActigraphTM to assess sleep problems.
Results The T-test analysis for sleep minuets revealed that
females had slept marginally more minutes than males (P = 0.05).
T-test analysis showed no significant difference in sleep parame-
ters between those using and not using any psychotropic agents.
Comorbidities analysis showed that children with comorbid con-
ditions slept more ( P = 0.01), went to bed later (P = 0.03) and had
more number of awakening ( P< 0.001) than participants without
comorbid conditions. Sleep minuets were correlated with deficit
in sensory cognitive awareness (r = 0.236, P = 0.035). Behavioural
deficit and number of awakening (r= 0.246, P = 0.028) were corre-
lated significantly.
Conclusion Our overall findings showed the association of sleep
problems and behavioral deficit and comorbidities in autism.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW79
Role of music and non-musical
techniques in self-guided emotional
regulation
R. Mohan ∗, N. Anand
Surrey and Borders Partnership NHS Foundation Trust, Child and
Adolescent Psychiatry, Guildford, United Kingdom