European Psychiatry - Volume 33 - March 2016

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S742 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Diagnosed of narcolepsy and treated with methylphenidate
immediate-release (IR) 10mg, alprazolam 1mg, and trazodone
100mg with good response.
Results Due to persistent symptoms, treatment was modi-
fied to osmotic-release oral system (OROS) – methylphenidate
resulting on a substantial weight loss (12 kg) and persistence of
symptoms. Another methylphenidate preparations were unsuc-
cessfully tested. Currently she continues treatment based on
methylphenidate release-release and she improved significantly
though she sometimes presented daytime sleepiness.
Discussion Recent studies have shown that a loss of the hypotha-
lamic neuropeptide hypocretin causes Narcolepsy with cataplexy
and that an autoimmune mechanism may be responsible for this
loss (related to HLA DQB*0602). Pathophysiology of narcolepsy
without cataplexy is less understood.
Although amphetamines and its derivatives are the mainstay of
management, therapies that involve hypocretine seems to be hope-
ful (intranasal, peripherical or hipocretin cell transplantation).
Monotherapy with GHB, H3 antagonist receptors, TRH analogs and
immunotherapy are also being studied.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Further reading
Gbolaga A, Rickards H. Narcolepsy: a review. Neuropsychiatr Dis
Treat 2011;7:507–18.
EV1231
Sleep quality among medical students
I. Gassara ∗, R. Ennaoui , N. Halwani , M. Turki ,
J. Aloulou , O. Amami
Hédi Chaker Hospital, Psychiatry, Sfax, Tunisia
∗ Corresponding author.
Introduction College students seem to be a population group that
is increasingly recognized to be at risk of having sleep difficul-
ties. Some studies revealed that medical students, in particular,
are believed to be more stressed and sleep deprived than their
non-medical peers.
Aim The present work aimed at investigating the quality of sleep
among medical students at the University College of Medicine in
Sfax, Tunisia.
Methods The study consisted of an anonymous, voluntary survey
for a sample of 74 students. A two-part questionnaire was used,
including demographic criteria and the Pittsburgh Sleep Quality
Index (PSQI), a self-rated instrument that measures sleep habits
for a month (a total score of 5 or greater is indicative of poor sleep
quality).
Results The average age was 24 years (range 19–33) with a sex
ratio almost equal to 1. In 47.3% of cases, students were married.
These latter had at least one child in34.2%of cases. A total of 39.4%of
the students reported being smokers, while 25.6% of themadmitted
having regular alcohol consumption.
Poor sleep quality was reported by 63.5% of students with a PSQI
average score of 9.32 ±3.64.
The most correlated factors with poor sleep quality were par-
enthood (P = 0.031), alcohol consumption (P = 0.004) and stressful
studies ( P = 0.02).
Conclusion Poor sleep quality was pervasive among surveyed
medical students and this seemed to be in relationship with some
factors. This study points to the need for further evaluation of medi-
cal students’ sleep problems in order to improve their performance
and their quality of life as well.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1232
How much does depressive mood
affect sleep for high school students?
S. Kim ∗, J. Park , H. Kim , T.K. Kim , Y. Min , J. Kim , J. Lee , J. Yang
Korea International High School KIS, Jeju, Bioscience research,
Seogwipo-si-Je-ju do, Republic of Korea
∗ Corresponding author.
Background This research examined gender variations in depres-
sive mood for high school students affected by emotional upset and
how such depressive mood affect their sleep quality.
Methods Research was conducted from September 2015 to Octo-
ber 2015. Both males and females were divided into normal group
and depressive group by Zung Self-rating Depression Scale (ZSDS).
Each group adopted the Pittsburgh Sleep Quality Index (PSQI) to
measure sleep quality.
Results Analysis was made on a total of 155 students, which
were 83 male students and 72 female. The average ZSDS for all
high school students was 43.38 and the average PSQI was 5.39. The
number of male students in the normal and depressive group who
were diagnosed with sleep disorder were 2 (3.8%) and 9 (29.0%),
respectively (P < 0.05). But the number of female students in the
normal and depressive group who were diagnosed with sleep dis-
order were 11 (32.4%) and 33 (86.8%), respectively (P < 0.05). Both
males and females shared a meaningful result over sleep latency,
sleep disturbance, use of sleep medication, and daytime functional
disturbance among 7 items of PSQI for sleep quality, and female
students had a significantly meaningful result over sleep duration,
habitual sleep effects (P < 0.05).
Conclusion This research showed that sleep quality of all high
school students was not too bad but it can be problematic for those
with depressive mood. Especially, female students were diagnosed
with sleep disorder more than male students.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1233
Studying the dreaming content in the
patients with methadone
maintenance therapy who were
admitted to the drug rehabilitation
centers in the city of Kerman in 2014
A. Mehdizadeh Zare Anari ∗, A. Ghaffari Nejad , A. Sabahi ,
D. Rashid Farokhi
Kerman university of medical sciences, Psychiatry, Kerman, Iran
∗ Corresponding author.
Introduction Drug addiction and relapse are a social destructive
phenomenon. The identification of factors associated with relapse
can help predict the relapse in the addicts. One of the important
factors for the people’s psychological dynamics analysis is the study
of dreams.
Methods andmaterials This scientific-comparative study is cross-
sectional. Among the addicts with methadone maintenance
therapy and their relatives who have referred to the private addic-
tion treatment centers and Shahid Beheshti Hospital in Kerman,
in 2014, a random sample of 110 patients (55 patients treated
with Methadone and 55 in control group) was selected and they
answered to the Hall/Van de Castle test and questionnaire of demo-
graphic characteristics. Data analysis was performed by SPSS18
software.
Findings The patients with methadone maintenance therapy
reported more non-verbal activities related to drug abuse and its
related activities than the control group in their dreams ( P = 0/001).
Patientswithmethadonemaintenance therapy sawmore unknown
places in their dreams (P = 0/001).