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S742

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Diagnosed of narcolepsy and treated with methylphenidate

immediate-release (IR) 10mg, alprazolam 1mg, and trazodone

100mg with good response.

Results

Due to persistent symptoms, treatment was modi-

fied to osmotic-release oral system (OROS) – methylphenidate

resulting on a substantial weight loss (12 kg) and persistence of

symptoms. Another methylphenidate preparations were unsuc-

cessfully tested. Currently she continues treatment based on

methylphenidate release-release and she improved significantly

though she sometimes presented daytime sleepiness.

Discussion

Recent studies have shown that a loss of the hypotha-

lamic neuropeptide hypocretin causes Narcolepsy with cataplexy

and that an autoimmune mechanism may be responsible for this

loss (related to HLA DQB*0602). Pathophysiology of narcolepsy

without cataplexy is less understood.

Although amphetamines and its derivatives are the mainstay of

management, therapies that involve hypocretine seems to be hope-

ful (intranasal, peripherical or hipocretin cell transplantation).

Monotherapy with GHB, H3 antagonist receptors, TRH analogs and

immunotherapy are also being studied.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Further reading

Gbolaga A, Rickards H. Narcolepsy: a review. Neuropsychiatr Dis

Treat 2011;7:507–18.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2215

EV1231

Sleep quality among medical students

I. Gassara

, R. Ennaoui , N. Halwani , M. Turki ,

J. Aloulou , O. Amami

Hédi Chaker Hospital, Psychiatry, Sfax, Tunisia

Corresponding author.

Introduction

College students seem to be a population group that

is increasingly recognized to be at risk of having sleep difficul-

ties. Some studies revealed that medical students, in particular,

are believed to be more stressed and sleep deprived than their

non-medical peers.

Aim

The present work aimed at investigating the quality of sleep

among medical students at the University College of Medicine in

Sfax, Tunisia.

Methods

The study consisted of an anonymous, voluntary survey

for a sample of 74 students. A two-part questionnaire was used,

including demographic criteria and the Pittsburgh Sleep Quality

Index (PSQI), a self-rated instrument that measures sleep habits

for a month (a total score of 5 or greater is indicative of poor sleep

quality).

Results

The average age was 24 years (range 19–33) with a sex

ratio almost equal to 1. In 47.3% of cases, students were married.

These latter had at least one child in34.2%of cases. A total of 39.4%of

the students reported being smokers, while 25.6% of themadmitted

having regular alcohol consumption.

Poor sleep quality was reported by 63.5% of students with a PSQI

average score of 9.32

±

3.64.

The most correlated factors with poor sleep quality were par-

enthood (

P

= 0.031), alcohol consumption (

P

= 0.004) and stressful

studies (

P

= 0.02).

Conclusion

Poor sleep quality was pervasive among surveyed

medical students and this seemed to be in relationship with some

factors. This study points to the need for further evaluation of medi-

cal students’ sleep problems in order to improve their performance

and their quality of life as well.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2216

EV1232

How much does depressive mood

affect sleep for high school students?

S. Kim

, J. Park , H. Kim , T.K. Kim , Y. Min , J. Kim , J. Lee , J. Yang

Korea International High School KIS, Jeju, Bioscience research,

Seogwipo-si-Je-ju do, Republic of Korea

Corresponding author.

Background

This research examined gender variations in depres-

sive mood for high school students affected by emotional upset and

how such depressive mood affect their sleep quality.

Methods

Research was conducted from September 2015 to Octo-

ber 2015. Both males and females were divided into normal group

and depressive group by Zung Self-rating Depression Scale (ZSDS).

Each group adopted the Pittsburgh Sleep Quality Index (PSQI) to

measure sleep quality.

Results

Analysis was made on a total of 155 students, which

were 83 male students and 72 female. The average ZSDS for all

high school students was 43.38 and the average PSQI was 5.39. The

number of male students in the normal and depressive group who

were diagnosed with sleep disorder were 2 (3.8%) and 9 (29.0%),

respectively (

P

< 0.05). But the number of female students in the

normal and depressive group who were diagnosed with sleep dis-

order were 11 (32.4%) and 33 (86.8%), respectively (

P

< 0.05). Both

males and females shared a meaningful result over sleep latency,

sleep disturbance, use of sleep medication, and daytime functional

disturbance among 7 items of PSQI for sleep quality, and female

students had a significantly meaningful result over sleep duration,

habitual sleep effects (

P

< 0.05).

Conclusion

This research showed that sleep quality of all high

school students was not too bad but it can be problematic for those

with depressive mood. Especially, female students were diagnosed

with sleep disorder more than male students.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2217

EV1233

Studying the dreaming content in the

patients with methadone

maintenance therapy who were

admitted to the drug rehabilitation

centers in the city of Kerman in 2014

A. Mehdizadeh Zare Anari

, A. Ghaffari Nejad , A. Sabahi ,

D. Rashid Farokhi

Kerman university of medical sciences, Psychiatry, Kerman, Iran

Corresponding author.

Introduction

Drug addiction and relapse are a social destructive

phenomenon. The identification of factors associated with relapse

can help predict the relapse in the addicts. One of the important

factors for the people’s psychological dynamics analysis is the study

of dreams.

Methods andmaterials

This scientific-comparative study is cross-

sectional. Among the addicts with methadone maintenance

therapy and their relatives who have referred to the private addic-

tion treatment centers and Shahid Beheshti Hospital in Kerman,

in 2014, a random sample of 110 patients (55 patients treated

with Methadone and 55 in control group) was selected and they

answered to the Hall/Van de Castle test and questionnaire of demo-

graphic characteristics. Data analysis was performed by SPSS18

software.

Findings

The patients with methadone maintenance therapy

reported more non-verbal activities related to drug abuse and its

related activities than the control group in their dreams (

P

= 0/001).

Patientswithmethadonemaintenance therapy sawmore unknown

places in their dreams (

P

= 0/001).