European Psychiatry - Volume 33 - March 2016

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S748 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
data was performed by means of the Chi 2 test. Statistical signifi-
cance was set at P ≤ 0.05.
Results We have already gathered data from more than 2000 ER
psychiatric consultations, including 495 suicide attempters. Pre-
liminary results suggest that these kinds of behaviours are more
common in subjects without psychiatric disorders but with clin-
ical history of previous contact with mental health services and
in psychopharmacological therapy. Reasons for self-harming are
associated with relational problems rather than psychiatric symp-
toms. Among Axis II diagnoses, almost half of cases are affected by
histrionic personality disorder.
Conclusions The results described above should be considered
as preliminary, as data collection and statistical analyses are still
ongoing. Anyway, the observed correlation between previous con-
tact withmental health services, socio-relational issues and suicide
attempt, and the significant frequency of attempts in histrionic per-
sonality disorders seem to be particularly interesting. Implications
will be discussed.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1250
Alcohol and substances acute
intoxication in a population of suicide
attempters
S. Di Marco ∗, I. Coppola , C. Delicato , E. Gattoni , A. Venesia ,
D. Marangon , G.C. Avanzi , L. Castello , C. Gramaglia ,
E. Torre , P. Zeppegno
1 SC Psichiatria, UPO, Università degli Studi del Piemonte Orientale,
Translational Medicine, Novara, Italy
2 SC Psichiatria, AOU, Maggiore della Carità, Translational Medicne,
Novara, Italy
3 SC Medicina d’Urgenza, UPO, Università degli Studi del Piemonte
Orientale, Dipartimento di Medicina Clinica e Sperimentale, Novara,
Italy
∗ Corresponding author.
Introduction The effects of psychotropic drugs and alcohol acute
intoxication are important risk factors for attempted suicide among
individuals with and without substance use disorder (SUD).
Aims The first aim of this study is describing the socio-
demographic features and clinical history of subjects who were
acutely intoxicated when attempting suicide. The second aim is to
compare their features with those of subjects without acute alcohol
and substances intoxication at suicide attempt time.
Methods Determinants of ER psychiatric consultations were
studied prospectively during the period 2008–2014 at the “Mag-
giore della Carità” Hospital in Novara, Italy. For each patient, a
data sheet was filled in by experienced psychiatrists, in order
to gather demographic features, psychiatric history and present
clinical issues like blood and urine dosage of amphetamine and
methamphetamine, cannabinoid, cocaine and alcohol. Comparison
of qualitative data was performed by means of the Chi2 test. Statis-
tical significance was set at P ≤ 0.05.
Results We collected a sample of 495 suicide attempters who
referred to our ER. Statistical analysis of demographic and clinical
data is still ongoing.
Conclusions Preliminary results point out that acute alcohol and
drugs intoxication at suicide attempt time is much more frequent
in subjects without a SUD. Implications will be discussed.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1251
Suicide attempt in alcohol use
disorder and Wernicke
encephalopathy: A case report
L. Espinosa ∗, A. Fortea , G. Oriolo , M. Balcells , C. Oliveras
Hospital Clinic, Psychiatry, Barcelona, Spain
∗ Corresponding author.
Background The relation between alcohol dependence and sui-
cidal behavior is well known and alcohol consumption is a risk
factor to take in consideration in order to prevent suicidal attempts.
Wernicke encephalopathy (WE) is a common acute neurological
disorder caused by thiamine deficiency frequently associated with
alcohol use disorder and often infra-diagnosed. Just few cases are
reported about the possible correlation between suicidal behaviour
and Wernicke encephalopathy.
Objective To describe the possible association between suicidal
attempts and Wernicke encephalopathy.
Methods We report the case of a 57 year old man, with past diag-
nosis of disthymia and amphetamine abuse disorder, and a history
of bariatric surgery, who was hospitalized in the intensive care unit
(ICU) of hospital clinic for a suicidal attempt by mean of metro
railway precipitation. He presented two episodes of psychomotor
agitation in the context of an abstinence syndrome that reverted
with midazolam continuous perfusion and clonazepam 8mg per
day. Consequently to medical improvement, he was moved to
Psychiatry Unit of Addictive Behavior and finally diagnosed with
alcohol use disorder.
Results In the physical exam, bilateral nystagmus and cerebel-
lar ataxia were observed. Signs of malnutrition were detected in
the blood analysis. In a brain magnetic resonance image, volume
deficits in the mammillary bodies, thalamus, cortex and corpus cal-
losum, as well as peri-aqueductal altered signal were observed, all
signs compatible with Wernicke encephalopathy diagnoses.
Conclusions Wernicke encephalopathy is a frequent concomitant
condition in patients with alcohol use disorder. The consequent
cognitive decline could represent an independent added risk factor
for suicidal behavior.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1252
Forecasting of suicides rate in Russia
using time series analysis
Y. Razvodovsky
Grodno State Medical University, Pathological Physiology, Grodno,
Belarus
Introduction Mortality forecasting has gained in importance in
recent decades. Time series methods are commonly used for long-
termmortality forecasting since thesemethods have the advantage
of being stochastic. The difficulty of suicides forecasting is related
to the fact that suicide is influenced by a large number of factors,
which can be hardly predicted for the long-term future.
Objectives This paper tests the possibility of forecasting the sui-
cides rate in Russia using the analysis of time series data from 1956
to 2010.
Methods Time series analytical modeling techniques autoregres-
sive integrated moving average (ARIMA) were used to forecast the
suicides rate in Russia. The data on age-adjusted sex-specific sui-
cidesmortality rates per 1,000,000 of the population are taken from
the Russian State Statistical Committee (Rosstat).
Results The two time series were well accounted for by a first-
order differencing procedure and the specification of a first-order
moving average parameter. The results suggest a declining trend in
suicides mortality for both sexes.