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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S56–S71

S65

Disclosure of interest

The author has not supplied his declaration

of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.962

Schizophrenia research: The necessary link

between psychopathology and clinical

neuroscience

W29

From Griesinger to DSM-V: Do we

need the diagnosis of schizophrenia?

A. Erfurth

1 ,

, G. Sachs

2

1

Otto-Wagner-Spital, 6th Psychiatric Department, Vienna, Austria

2

Medical University of Vienna, Department of Psychiatry and

Psychotherapy, Vienna, Austria

Corresponding author.

The dichotomy between “dementia praecox” and “manic-

depressive insanity” by Emil Kraepelin is one of the milestones of

nosology in psychiatry

[1] .

This dichotomy reflects the necessity – particularly in the absence

of effective treatment in Kraepelin’s time – to differentiate (and to

predict) the functional outcome of individual patients. Since Krae-

pelin’s original division particularly the influence of Kurt Schneider

has led to a full acknowledgment of the dichotomy in both ICD and

DSM.

While this division has proven to be clinically useful, alternatives

have been proposed covering a large spectrum from the idea of uni-

tary psychosis as inWilhelmGriesinger and Klaus Conrad to further

subdivisions as in Karl Leonhard. Recent research in neuroscience

suggests the presence of an overlap between schizophrenia and

other psychiatric disorders

[2–4] .

Disclosure of interest

The author has not supplied his declaration

of competing interest.

References

[1] Kraepelin E. Psychiatrie. 6th edition Leipzig: J.A. Barth; 1899.

[2] Smoller JW, et al. Lancet 2013;381:1371–9.

[3] Lee SH, et al. Nat Genet 2013;45:984–94.

[4] Padmanabhan JL, et al. Schizophr Bull 2015;41(1):154–62.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.963

W30

Role of psychopathology in

elucidating the underlying neural

mechanisms

F. Oyebode

Birmingham, United Kingdom

Introduction

Psychopathology is the systematic study of abnor-

mal subjective experience and behaviour and it aims to give precise

description, categorisation and definition of abnormal subjective

experiences.

Aim

I aim to demonstrate that the most appropriate approach to

elucidating the biological origins of psychiatric disorders is firstly to

identify elementary abnormal phenomena and then to relate these

to their underlying neural mechanisms. I will exemplify this by

drawing attention to studies of Delusional Misidentification Syn-

dromes (DSM).

Results

I will show that there are impairments in face recogni-

tion memory in individuals with DSM without impairments in the

recognition of emotion and that there are abnormalities of right

hemisphere function and of the autonomic recognition pathways

that determine sense of familiarity.

Conclusions

Basic psychopathological phenomena are more

likely to throw light on the basic neuralmechanisms that are impor-

tant in psychiatric disorders than studying disease level categories.

Disclosure of interest

The author has not supplied his declaration

of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.964

W31

The role of cognition in the

psychopathology of schizophrenia:

Assessment and treatment options

G. Sachs

1 ,

, I. L

asser

1 , B. W

inklbaur

1 , E. M

aihofer

2 , A. E

rfurth

2

1

Medical University of Vienna, Department of Psychiatry and

Psychotherapy, Vienna, Austria

2

Otto Wagner Spital, Vienna, Austria

Corresponding author.

Cognitive dysfunction is a characteristic feature of patients

with schizophrenia. Traditionally, the main distinction between

“dementia praecox” and “manic-depressive insanity” was in fact

the cognitive outcome during the course of the disease

[1] .

For the assessment of cognitive dysfunction both large, detailed

instruments

[2] a

nd brief screening scales for quick and multiple

use

[3,4] a

re available.

Recently, the role of social cognition has been thoroughly examined

showing differential effects

[5] .

Treatment of cognitive dysfunction in schizophrenia comprises

adherence to a therapy with atypical antipsychotics as well as spe-

cific treatment programs for cognitive

[6] a

nd social cognitive

[7,8]

dysfunction.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

References

[1] Kraepelin E. Psychiatrie. 6th edition Leipzig: J.A. Barth; 1899.

[2] Green MF, et al. Am J Psychiatry 2014;171(11):1151–4.

[3] Sachs G, et al. Eur Psychiatry 2011;26(2):74–7.

[4] Cuesta MJ, et al. Schizophr Res 2011;130(1–3):137–42.

[5] Green MF, et al. Nat Rev Neurosci 2015;16(10):620–31.

[6] Wykes T, et al. Am J Psychiatry 2011;168(5):472–85.

[7] Kurtz MM, et al. Clin Psychol Rev 2015 [Epub ahead of print].

[8] Sachs G, et al. Schizophr Res 2012;138(2–3):262–7.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.965

Shaping the future of healthcare through

innovation and technology

W32

New research in outcome

management using apps and DSM-5

measures. Preliminary results

V.J.A. Buwalda

Vrije Universiteit/Victas addiction Center, Psychiatry, Amsterdam,

Netherlands

The presentation is about the use of outcome measurements in

combination of a newly developed app that enables psychiatrists

and patients track the progress of their treatment process and

adjust it if needed in an shared decision fashion.

In 2013 the fifth edition of the Diagnostic and Statistical Manual

of Mental Disorders was introduced. Around the same time there

was the start of a paradigm shift in healthcare which increased the

focus on patient involvement in individual health care decision-

making and onmeasuring and improving outcomes of care (Sederer