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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

S629

EV874

How strange is everything

T. Casanova

, J.A. Blanco Garrote , R. Hernández Antón

,

A. Rodríguez Campos , S. Cepedello Pérez , S. Gómez Sánchez ,

G. Isidro García , L. Rodríguez Andrés , M. Hernández García ,

C. Noval Canga , A. Alvarez Astorga , H. De la Red Gallego

Hospital Clínico Universitario de Valladolid, Psiquiatría, Valladolid,

Spain

Corresponding author.

Introduction

Twenty-year-old woman. In summary, we noted

that a year ago, she had an episode of psychotic features secondary

to cannabis in London. She then presented a depressing picture.

In the current episode, the patient is anxious to be in a kind of

dream. She says it is able to communicate through thought, and

says his mind thinks fast. Make interpretations, giving meaning to

everything that is new. Refer to hear voices in his head of his chil-

dren. It is told with great emotional impact. Absence of previous

consumption.

Objectives

It presents the case of a patient with psychotic symp-

toms treated early.

Methods

Psychopathological examination: conscious, oriented,

collaborative. Good looks and touch. Tachypsychia and tachylalia.

Speech inconsistent with loose associations of ideas. Dysphoria

with emotional lability and continuous crying, feelings of guilt.

Great anxiety component. Phenomena of derealization and deper-

sonalization. Delusional interpretations of objects. Alterations of

the experience of self. Possible auditory hallucinations. Insomnia.

Results

During treatment with olanzapine, income starts to 20

mg and then proceeds to therapeutic change aripiprazolewith good

response, objectifying a partial remission of symptoms, quiet and

adequate meeting, being aware of what happened.

Conclusions

Schizoaffective disorder describes a mental disorder

characterized by recurrent episodes of mood changes underway

in all cases with psychotic symptoms. People with schizoaffective

disorder are more likely to return to their previous level of function

than do people with other psychotic disorders.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1859

EV875

Gut feeling

C. Cotta

1 ,

, G. Jesus

2

, V. Vila Nova

3

, C. Moreira

2

1

Centro Hospitalar Barreiro-Montijo, Psychiatry, Barreiro, Portugal

2

Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisbon,

Portugal

3

Centro Hospitalar Barreiro Montijo, Psychiatry, Barreiro, Portugal

Corresponding author.

Introduction

There is growing evidence of the importance of

nutrition in mental disorders. Gut microbiota, influenced by envi-

ronmental factors such as diet and stress, has been proposed as one

of the players on a dynamic called gut-brain axis, which is thought

to have an influence on behaviour and mental health.

Objectives and aims

To summarize recent evidence on the topic,

and its potential role in psychiatric interventions.

Methods

The authors review updated literature collected from

online scientific databases.

Results

The development of the brain itself has been shown to

be influenced by the gut microbiome. Research demonstrates that

the composition of the microbiota has influence on behaviour

through neuroendocrine and other neuroactive messengers pro-

duction by the bacteria within the gut lumen. Studies in germ-free

animals, animals exposed to bacterial infections, probiotic suple-

ments or antibiotic drugs suggest a role for the gut microbiota in

the regulation of anxiety, mood, cognition and pain. The gut micro-

biome has been implicated in brain disorders including anxiety

and depression, multiple sclerosis, Alzheimer’s disease, Parkinson’s

disease, and autism.

Conclusions

The treatment of mental disorders is usually based

on pharmacological and psychotherapeutic interventions, and lit-

tle attention is given to dietary interventions. The emerging field

of research focused on the human microbiome suggests an impor-

tant role for the gut microbiota in influencing brain development,

behaviour and mood in humans, and points new strategies for

developing novel therapeutics for mental disorders.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1860

EV876

Borderline personality disorder and

automatic processing of valence and

self-other relevance information

U.S. Donges

, B. Dukalski , A. Kersting , T. Suslow

University of Leipzig, psychosomatic medicine and psychotherapy,

Leipzig, Germany

Corresponding author.

Introduction

Enhanced sensitivity to emotion stimuli and poor

differentiation between self and others have been proposed to be

important features of borderline personality disorder (BPD). Auto-

matic processing of affective stimuli provides information about

valence (positive vs. negative) and relevance of valence (self vs.

other).

Aims

The objectives of our study were to investigate efficiency of

automatic processing of valence and relevance at a semantic level

in BPD compared to healthy individuals.

Methods

A masked affective priming task, varying valence and

relevance of prime and target adjectives, was administered to 33

women with BPD and 33 healthy women. The forward and back-

ward masked primes were shown for 50ms. Subjects had the task

to evaluate target words.

Results

In the whole sample, a significant affective priming effect

and a significant relevance priming effect occurred. Presence of

comorbiddepressive disorderwas positively correlatedwith extent

of affective priming. BPD patients did not differ in affective priming

fromhealthy individuals but they exhibited less relevance priming.

Conclusions

According to our data efficiency of automatic recog-

nition and processing of valence information at a semantic level

is not impaired in BPD compared to healthy individuals. However,

BPD patients appear to be less able to perceive and differentiate

automatically self- vs. other-relevance during the perception of

affective information than healthy controls. The present results

indicate that patients with BPD could manifest impairments of

self-other differentiation already at a very early or basic stage of

emotion processing.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1861

EV877

A life tiptoeing: Being a significant

other to persons with borderline

personality disorder

S. Ekdahl

1 ,

, I. E

wa

1 , P. K

ent-Inge

2 , S. M

ats

3

1

Malmö university, faculty of health & society, the department of

care science, Malmö, Sweden

2

Red Cross university college, psychiatric nursing, Stockholm, Sweden

3

Karolinska institute, department of neurobiology- care sciences and

society, Stockholm, Sweden

Corresponding author.