European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S629
EV874
How strange is everything
T. Casanova ∗, J.A. Blanco Garrote , R. Hernández Antón
A. Rodríguez Campos , S. Cepedello Pérez , S. Gómez Sánchez ,
G. Isidro García , L. Rodríguez Andrés , M. Hernández García ,
C. Noval Canga , A. Alvarez Astorga , H. De la Red Gallego
Hospital Clínico Universitario de Valladolid, Psiquiatría, Valladolid,
Spain
∗ Corresponding author.
Introduction Twenty-year-old woman. In summary, we noted
that a year ago, she had an episode of psychotic features secondary
to cannabis in London. She then presented a depressing picture.
In the current episode, the patient is anxious to be in a kind of
dream. She says it is able to communicate through thought, and
says his mind thinks fast. Make interpretations, giving meaning to
everything that is new. Refer to hear voices in his head of his chil-
dren. It is told with great emotional impact. Absence of previous
consumption.
Objectives It presents the case of a patient with psychotic symp-
toms treated early.
Methods Psychopathological examination: conscious, oriented,
collaborative. Good looks and touch. Tachypsychia and tachylalia.
Speech inconsistent with loose associations of ideas. Dysphoria
with emotional lability and continuous crying, feelings of guilt.
Great anxiety component. Phenomena of derealization and deper-
sonalization. Delusional interpretations of objects. Alterations of
the experience of self. Possible auditory hallucinations. Insomnia.
Results During treatment with olanzapine, income starts to 20
mg and then proceeds to therapeutic change aripiprazolewith good
response, objectifying a partial remission of symptoms, quiet and
adequate meeting, being aware of what happened.
Conclusions Schizoaffective disorder describes a mental disorder
characterized by recurrent episodes of mood changes underway
in all cases with psychotic symptoms. People with schizoaffective
disorder are more likely to return to their previous level of function
than do people with other psychotic disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV875
Gut feeling
C. Cotta ∗, G. Jesus , V. Vila Nova , C. Moreira
1 Centro Hospitalar Barreiro-Montijo, Psychiatry, Barreiro, Portugal
2 Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisbon,
Portugal
3 Centro Hospitalar Barreiro Montijo, Psychiatry, Barreiro, Portugal
∗ Corresponding author.
Introduction There is growing evidence of the importance of
nutrition in mental disorders. Gut microbiota, influenced by envi-
ronmental factors such as diet and stress, has been proposed as one
of the players on a dynamic called gut-brain axis, which is thought
to have an influence on behaviour and mental health.
Objectives and aims To summarize recent evidence on the topic,
and its potential role in psychiatric interventions.
Methods The authors review updated literature collected from
online scientific databases.
Results The development of the brain itself has been shown to
be influenced by the gut microbiome. Research demonstrates that
the composition of the microbiota has influence on behaviour
through neuroendocrine and other neuroactive messengers pro-
duction by the bacteria within the gut lumen. Studies in germ-free
animals, animals exposed to bacterial infections, probiotic suple-
ments or antibiotic drugs suggest a role for the gut microbiota in
the regulation of anxiety, mood, cognition and pain. The gut micro-
biome has been implicated in brain disorders including anxiety
and depression, multiple sclerosis, Alzheimer’s disease, Parkinson’s
disease, and autism.
Conclusions The treatment of mental disorders is usually based
on pharmacological and psychotherapeutic interventions, and lit-
tle attention is given to dietary interventions. The emerging field
of research focused on the human microbiome suggests an impor-
tant role for the gut microbiota in influencing brain development,
behaviour and mood in humans, and points new strategies for
developing novel therapeutics for mental disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV876
Borderline personality disorder and
automatic processing of valence and
self-other relevance information
U.S. Donges∗, B. Dukalski , A. Kersting , T. Suslow
University of Leipzig, psychosomatic medicine and psychotherapy,
Leipzig, Germany
∗ Corresponding author.
Introduction Enhanced sensitivity to emotion stimuli and poor
differentiation between self and others have been proposed to be
important features of borderline personality disorder (BPD). Auto-
matic processing of affective stimuli provides information about
valence (positive vs. negative) and relevance of valence (self vs.
other).
Aims The objectives of our study were to investigate efficiency of
automatic processing of valence and relevance at a semantic level
in BPD compared to healthy individuals.
Methods A masked affective priming task, varying valence and
relevance of prime and target adjectives, was administered to 33
women with BPD and 33 healthy women. The forward and back-
ward masked primes were shown for 50ms. Subjects had the task
to evaluate target words.
Results In the whole sample, a significant affective priming effect
and a significant relevance priming effect occurred. Presence of
comorbiddepressive disorderwas positively correlatedwith extent
of affective priming. BPD patients did not differ in affective priming
fromhealthy individuals but they exhibited less relevance priming.
Conclusions According to our data efficiency of automatic recog-
nition and processing of valence information at a semantic level
is not impaired in BPD compared to healthy individuals. However,
BPD patients appear to be less able to perceive and differentiate
automatically self- vs. other-relevance during the perception of
affective information than healthy controls. The present results
indicate that patients with BPD could manifest impairments of
self-other differentiation already at a very early or basic stage of
emotion processing.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV877
A life tiptoeing: Being a significant
other to persons with borderline
personality disorder
S. Ekdahl ∗ wa ent-Inge ats
1 Malmö university, faculty of health & society, the department of
care science, Malmö, Sweden
2 Red Cross university college, psychiatric nursing, Stockholm, Sweden
3 Karolinska institute, department of neurobiology- care sciences and
society, Stockholm, Sweden
∗ Corresponding author.