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S576

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

Methods

A sample of male offenders incarcerated in Italian jails,

and a sample of community-dwelling men, were administered the

Self-Report Psychopathy Scale (SRP-4; Paulhus et al., 2015) and the

Pathological Narcissism Inventory (PNI; Pincus et al., 2009).

Results

As expected, levels of both narcissism and psychopathy

were significantly higher in the offender sample. Narcissism and

psychopathy were only partly related, with correlations ranging

from low to moderate in size, and differential pattern of associ-

ations between selected dimensions emerged consistently with

theoretical models and in line with prior studies.

Conclusions

Psychopathy and narcissism are two separate syn-

dromes, which share similar aspects but also present distinct

features and this is likely to explain their partial overlap. Future

studies should take a closer look at how facets of psychopathy

and narcissism relate across different samples (e.g., also examining

female offender samples).

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1691

EV707

Dealing with shame – the

‘Psychopathic Way’: Preliminary

investigation for a new developmental

framework of psychopathic traits

P. Velotti

1 ,

, M. D’aguanno

2

, C. Garofalo

3

, G. Rogier

2

1

University of Genoa, Educational Sciences, Psychology Unit, Genova,

Italy

2

University Sapienza, Psychology, Rome, Italy

3

Tilburg University, Psychology, Tilburg, Netherlands

Corresponding author.

Although individuals with psychopathic traits are deemed as

immune to emotional experiences, in recent year, some authors

have advanced the hypothesis that a pervasive pattern of emo-

tiondysregulationmay characterize the developmental trajectories

leading to a psychopathic personality structure. Shame has been

proposed as crucial emotions to understand psychopathy. It has

been argued that people, who often experience shame feelings dur-

ing their childhood, may develop adaptive strategies to cope with

them, which lead to maladaptive strategies to regulate shame feel-

ings in adulthood. These maladaptive strategies may explain the

increased likelihood for these individuals to violence when feel-

ing ashamed. Whether these mechanisms may also explain the

presence of high psychopathic traits remains a clinically valid the-

oretical hypothesis, which lacks empirical support.

Objective

To investigate whether maladaptive strategies to cope

with shame feelings were associated with psychopathic traits.

Aims

To examine the association between four maladaptive

shame coping were positively related with psychopathic traits.

Methods

A sample of male offenders incarcerated in Italian jails

completed the Self-Report Psychopathy Scale (Paulhus et al., 2015)

and the Compass of Shame Scale (Elison et al., 2006).

Results

As hypothesized, maladaptive shame regulation strate-

gies did predict psychopathic traits in the offender sample

examined. Specifically, significant and meaningful associations

occurred between avoidance and attack other coping styles and

psychopathic traits.

Conclusions

The present study is among the first in providing evi-

dence of a possible relationship between maladaptive strategies to

cope with shame feelings and psychopathic traits, and such link can

be informative to tailor treatment programs for these hard-to-treat

patients.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1692

EV708

Increasing polyvalent illicit drug

abuse and increasing dropout rates in

forensic in-patient treatment – is

there a link?

F. Wedegaertner

1 ,

, A. Weber

2

, M. von der Haar

3

1

Medizinische Hochschule Hannover, Psychiatry, Hannover,

Germany

2

MRVZN Bad Rehburg, Forensic Psychiatry, Rehburg, Germany

3

MRVZN Bad Rehburg, Forensic Psychiatry, Bad Rehburg, Germany

Corresponding author.

For a cross-sectional survey of forensic treatment of substance

use disorders in Germany, 77,220 patient records were collected

between 1994 and 2012. Results show that polyvalent illicit drug

abuse is an increasing phenomenon in patients referred to foren-

sic treatment by the courts in Germany. The percentage of these

patients has risen from32 to 68%. Patients drop out of forensic treat-

ment as not successfully treatable because of relapses or repetitive

disciplinary infractions or if the maximum duration of imprison-

ment is reached without positive medical and/or legal prognosis.

While dropout rates because of ill treatment success have risen

from34% to 47%, so has the average length of stay in cross-sectional

samples from 10 to 15 months. The percentage of those released at

maximum duration without positive prognosis has more than dou-

bled. The length of parallel prison terms pronounced by the courts

has risen from 31 to 44 months during the period of observation.

This has led to high occupancy in forensic institutions. High occu-

pancy poses a challenge for the individuality and thoroughness of

the treatment approach and may influence success rates. Changing

legislation and public pressure need to be considered when lengths

of stay are interpreted. We are going to discuss the role of changing

morbidity in the treatment of substance use disorders in the gen-

eral population and in the forensic sample between 1994 and 2012

and how institutions prepare for the specific needs of the changing

clientele.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1693

Genetics & molecular neurobiology

EV709

Differential binding of CREB, USF, and

c-Myc to the calreticulin human

specific –220C may be linked with the

evolution of higher brain functions in

human

S. Farashi

University Medical Center Utrecht, Translational Neuroscience,

Utrecht, Netherlands

Introduction

We have previously reported a human-specific

nucleotide in the promoter sequence of the calreticulin (

CALR

) gene

at position –220C, which is the site of action of valproic acid.

Objectives

Reversion of this nucleotide to the ancestral type,

–220A, co-occurs with severe deficit in higher brain cognitive func-

tions.

Aims

In the current study, we compare the pattern of protein

binding between –220C and –220A.

Methods

Antibodies reactive against transcription factors CREB,

USF, and c-Myc were used to identify the specific proteins involved