European Psychiatry - Volume 33 - March 2016

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S576 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
Methods A sample of male offenders incarcerated in Italian jails,
and a sample of community-dwelling men, were administered the
Self-Report Psychopathy Scale (SRP-4; Paulhus et al., 2015) and the
Pathological Narcissism Inventory (PNI; Pincus et al., 2009).
Results As expected, levels of both narcissism and psychopathy
were significantly higher in the offender sample. Narcissism and
psychopathy were only partly related, with correlations ranging
from low to moderate in size, and differential pattern of associ-
ations between selected dimensions emerged consistently with
theoretical models and in line with prior studies.
Conclusions Psychopathy and narcissism are two separate syn-
dromes, which share similar aspects but also present distinct
features and this is likely to explain their partial overlap. Future
studies should take a closer look at how facets of psychopathy
and narcissism relate across different samples (e.g., also examining
female offender samples).
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV707
Dealing with shame – the
‘Psychopathic Way’: Preliminary
investigation for a new developmental
framework of psychopathic traits
P. Velotti ∗, M. D’aguanno , C. Garofalo , G. Rogier
1 University of Genoa, Educational Sciences, Psychology Unit, Genova,
Italy
2 University Sapienza, Psychology, Rome, Italy
3 Tilburg University, Psychology, Tilburg, Netherlands
∗ Corresponding author.
Although individuals with psychopathic traits are deemed as
immune to emotional experiences, in recent year, some authors
have advanced the hypothesis that a pervasive pattern of emo-
tiondysregulationmay characterize the developmental trajectories
leading to a psychopathic personality structure. Shame has been
proposed as crucial emotions to understand psychopathy. It has
been argued that people, who often experience shame feelings dur-
ing their childhood, may develop adaptive strategies to cope with
them, which lead to maladaptive strategies to regulate shame feel-
ings in adulthood. These maladaptive strategies may explain the
increased likelihood for these individuals to violence when feel-
ing ashamed. Whether these mechanisms may also explain the
presence of high psychopathic traits remains a clinically valid the-
oretical hypothesis, which lacks empirical support.
Objective To investigate whether maladaptive strategies to cope
with shame feelings were associated with psychopathic traits.
Aims To examine the association between four maladaptive
shame coping were positively related with psychopathic traits.
Methods A sample of male offenders incarcerated in Italian jails
completed the Self-Report Psychopathy Scale (Paulhus et al., 2015)
and the Compass of Shame Scale (Elison et al., 2006).
Results As hypothesized, maladaptive shame regulation strate-
gies did predict psychopathic traits in the offender sample
examined. Specifically, significant and meaningful associations
occurred between avoidance and attack other coping styles and
psychopathic traits.
Conclusions The present study is among the first in providing evi-
dence of a possible relationship between maladaptive strategies to
cope with shame feelings and psychopathic traits, and such link can
be informative to tailor treatment programs for these hard-to-treat
patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV708
Increasing polyvalent illicit drug
abuse and increasing dropout rates in
forensic in-patient treatment – is
there a link?
F. Wedegaertner ∗, A. Weber , M. von der Haar
1 Medizinische Hochschule Hannover, Psychiatry, Hannover,
Germany
2 MRVZN Bad Rehburg, Forensic Psychiatry, Rehburg, Germany
3 MRVZN Bad Rehburg, Forensic Psychiatry, Bad Rehburg, Germany
∗ Corresponding author.
For a cross-sectional survey of forensic treatment of substance
use disorders in Germany, 77,220 patient records were collected
between 1994 and 2012. Results show that polyvalent illicit drug
abuse is an increasing phenomenon in patients referred to foren-
sic treatment by the courts in Germany. The percentage of these
patients has risen from32 to 68%. Patients drop out of forensic treat-
ment as not successfully treatable because of relapses or repetitive
disciplinary infractions or if the maximum duration of imprison-
ment is reached without positive medical and/or legal prognosis.
While dropout rates because of ill treatment success have risen
from34% to 47%, so has the average length of stay in cross-sectional
samples from 10 to 15 months. The percentage of those released at
maximum duration without positive prognosis has more than dou-
bled. The length of parallel prison terms pronounced by the courts
has risen from 31 to 44 months during the period of observation.
This has led to high occupancy in forensic institutions. High occu-
pancy poses a challenge for the individuality and thoroughness of
the treatment approach and may influence success rates. Changing
legislation and public pressure need to be considered when lengths
of stay are interpreted. We are going to discuss the role of changing
morbidity in the treatment of substance use disorders in the gen-
eral population and in the forensic sample between 1994 and 2012
and how institutions prepare for the specific needs of the changing
clientele.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Genetics & molecular neurobiology
EV709
Differential binding of CREB, USF, and
c-Myc to the calreticulin human
specific –220C may be linked with the
evolution of higher brain functions in
human
S. Farashi
University Medical Center Utrecht, Translational Neuroscience,
Utrecht, Netherlands
Introduction We have previously reported a human-specific
nucleotide in the promoter sequence of the calreticulin (CALR ) gene
at position –220C, which is the site of action of valproic acid.
Objectives Reversion of this nucleotide to the ancestral type,
–220A, co-occurs with severe deficit in higher brain cognitive func-
tions.
Aims In the current study, we compare the pattern of protein
binding between –220C and –220A.
Methods Antibodies reactive against transcription factors CREB,
USF, and c-Myc were used to identify the specific proteins involved