European Psychiatry - Volume 33 - March 2016

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S474 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
sociodemographic factors, depression comorbidity and antidepres-
sive treatment.
Results One thousand four hundred and fifty-two patients
matched DSM-V delusional disorder criteria. 49,8% of our sample
were women. Average following period was 9 years and 1 month,
with an average of 0,84 hospitalizations. The prevalence of depres-
sion in patients with delusional disorders was 31,9%. 67,5% of them
received some kind of antidepressive treatment. The antidepres-
sive drugs most frequently used were selective serotonin reuptake
inhibitors.
Conclusions Depression is a highly prevalent condition among
patients with delusional disorder. Most of them are on antidepres-
sive treatment, the most employed of which is based on selective
serotonin reuptake inhibitors. Comorbid depression can have an
important impact on the course of delusional disorder. A correct
diagnosis and treatment should be made to help improve the prog-
nosis and life quality of these patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV393
Anxiety disorders and substance abuse
I. Prieto Sánchez ∗, M.D.L.C. Ramírez Domínguez ,
S. Fernández León , M. Reina Domínguez , N. Garrido Torres ,
A. Rodríguez Martínez , A.S. Biedma Martín , C. González Macías
Complejo Hospitalario Universitario de Huelva Juan Ramón Jimenez,
Unidad de Salud Mental, Huelva, Spain
∗ Corresponding author.
Introduction Patients with anxiety disorders aremore vulnerable
to develop other comorbid conditions. In particular, large epi-
demiological studies show a strong association between different
anxiety disorders and substance use disorders.
Objectives To showthe prevalence ofmajor anxiety disorders and
the consumption of different substances. As well as the particu-
lar characteristics of this dual diagnosis and treatments that have
proven more effective.
Methods Exhaustive review of all the material published on this
topic in the recent years.
Conclusions Nearly 24% of patients with anxiety disorder suffer
from a comorbid substance disorder use in their lifetime (17.9%
diagnosis of alcohol abuse or dependence diagnosis and 11.9% of
abuse or dependence on other drugs). Dual patients show a number
of distinctive features, such as more frequency in males, family his-
tory of alcohol or other substances abuse and behavioral problems,
early parental loss among others.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV394
Dual diagnosis (Depression and
addictions): Special considerations
I. Prieto Sánchez ∗, M.D.L.C. Ramírez Domínguez ,
A. Rodríguez Martínez , N. Garrido Torres , M. Reina Domínguez ,
A.S. Biedma Martín , C. González Macías
Complejo Hospitalario Universitario de Huelva Juan Ramón Jimenez,
Unidad de Salud Mental, Huelva, Spain
∗ Corresponding author.
Introduction Dual diagnosis is a growing problem in Western
society, despite which there are no large studies examining this
issue, nor specific protocols to address them.
Objectives To raise awareness of the importance of dual diagno-
sis both its prevalence and special features that presents need a
different performance plan from them separately.
Methods Comprehensive literature review of all published in the
last 2 years, as well as the specific features.
Conclusion Dual diagnosis has very specific characteristics that
we must know in order to develop therapeutic strategies adapted
to the present conditions.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV395
Health-related quality of life in
patients with moderate-severe
psoriasis: Preliminary results on the
role of psychopathology and coping
strategies in a cohort of patients
M. Fabrazzo ∗, V. De Santis , R.V. Puca , F. Romano ,
M. Arrigo , V. Cioffi , F. Catapano , A. Lo Schiavo
1 University of Naples SUN, department of psychiatry, Naples, Italy
2 University of Naples SUN, department of dermatology, Naples, Italy
∗ Corresponding author.
Psoriasis is a multisystem inflammatory disease associated to
several comorbidities with a significant impact on interper-
sonal and social life. Depression, anxiety symptoms and suicidal
ideation–due to psychological distress–are frequently reported.
The aim of the study was to assess whether psychological
factors–psychopathology, perceived health status and coping
strategies–together with clinical and sociodemographic factors,
were independent predictors of Quality of Life (QoL) in adult psori-
atic patients on topical and/or systemic pharmacological therapy. A
cohort of 87 patients (53 Mand 34 F), whosemean agewas 46± 22
years, was analyzed. Coping responses were assessed by COPE and
general psychopathology by Self-Reported-Symptom Inventory
Revised (SCL-90), while HAM-D and HAM-A evaluated depressive
and anxiety symptoms. In addition, perceived health status and
QoL were analyzed by Short-Form-36 (SF-36) while the disease’s
burden assessed by PSODISK. Univariate analyses were performed
for each variable to explore the relationship with QoL. Preliminary
results indicated that, although not severe, anxiety and depres-
sive symptoms were the most reported among patients along with
somatization and obsessive-compulsivity. Female patients used
more frequently mental disengagement, focus on and venting of
emotions, use of instrumental social support and religious cop-
ing. Physical pain and mental health, instead, greatly affected QoL
of subjects in a negative manner. PSODISK data analysis showed
that general health, itching, serenity, shame and degree of exten-
sion of the disease on the skin were the most compromised areas.
Moreover, correlation analysis indicated that a worse perception of
patients’ health status was associated to poor QoL.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV396
Epilepsy and self-esteem
M. Turki ∗ ouchhima Halouani urki
N. Bouzidi Dammak Amami hiri
1 Habib Bourguiba university hospital, neurology department, Sfax,
Tunisia
2 Hedi Chaker university hospital, psychiatry department, Sfax,
Tunisia
∗ Corresponding author.
Introduction Epilepsy is a public health problemthat often affects
personal and social patients’ life. Self-esteem, an important factor
contributing to psychosocial well-being, is generally disrupted in
epilepsy.