European Psychiatry - Volume 33 - March 2016

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S208 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348
aggression protocol in their hospitals, we think that a prevention
and supporting guideline should be design for improve this preva-
lent situation.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW270
Abnormal amygdala functional
connectivity during an fMRI
expectancy task in pedophilia
I. Ristow ∗ i . Demenescu Walter eier
T. Kruger , B. Schiffer , J. Ponseti , M. Walter
1 Magdeburg, Germany
2 CANLAB Magdeburg, Department of Psychiatry, Magdeburg,
Germany
3 Clinic for Psychiatry and Psychotherapy, Clinic for Psychiatry and
Psychotherapy, Berlin, Germany
4 Institute for Sexual Medicine and Sexual Science, Institute for Sexual
Medicine and Sexual Science, Berlin, Germany
5 Research Group Clinical Psychology and Sexual Medicine, Center for
Mental Health, Clinic for Psychiatry, Sociopsychiatry and
Psychotherapy, Hannover, Germany
6 Institute for Forensic Psychiatry of the University Duisburg-Essen,
Institute for Forensic Psychiatry of the University Duisburg-Essen,
Essen, Germany
7 Institute for Sexualmedicine and Forensic Psychiatry and
Psychotherapy, Institute for Sexualmedicine and Forensic Psychiatry
and Psychotherapy, Kiel, Germany
∗ Corresponding author.
Introduction Pedophilia is a disorder where sexual preferences
of adults are directed towards children. This disorder impacts soci-
ety with 1–2 out of every 10 children being sexually approached
by an adult, often resulting in prolonged negative psychological
effects. Prior research reported structural and functional amygdala
alterations in pedophilia. As the neurophenomenological model of
sexual arousal suggests the importance of the amygdala in the emo-
tional component, we focused on amygdala functional connectivity
in pedophilia.
Aims To investigate amygdala functional connectivity (FC) mod-
ulated by expectancy and salient stimuli in pedophilic patients.
Methods Thirteen pedophilic patients and 13 matched healthy
controls underwent a salience expectancy task in a 7T ultra
high fMRI study. Subjects perceived pictures of naked adults and
children. Half of the pictures were preceded by an expectancy
cue. Participants were instructed to actively expect the pic-
ture depending on the cue. We conducted psychophysiological
analysis (PPI) to examine amygdala FC changes in two amyg-
dala sub-regions for child/adult stimuli during the expectancy
period and the visual stimuli consummation period using as seed
regions the basolateral (BLA) and central nucleus of the amygdala
(CeA).
Results Healthy controls, relative to patients showed significant
stronger left CeA to right post-central gyrus FC during expectancy
of adult > child picture. For picture condition (adult > child picture)
we found significant stronger left CeA to left dorsolateral prefrontal
cortex FC in patients compared to healthy controls.
Conclusion These findings add to the recent literature by indi-
cating that amygdala dysfunctional connectivity is involved in
development of deviant sexual behavior.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW271
Restrictive measures in psychiatry
M. Rodríguez Merino ∗, J.J. Arechederra Aranzadi ,
M.I. López-Ibor Alcocer
Dr. López Ibor Neuropsychiatric Institute, Psychiatry, Madrid, Spain
∗ Corresponding author.
Introduction Informed consent is guarantor of the three princi-
ples that guide the professional activity of physicians concretely,
information, comprehension and volunteerism, based on bioethi-
cal values of autonomy, non-maleficence, beneficence and justice.
Psychopathological alterations undermine the capacity to con-
sent treatment, requiring, sometimes, restrictive measures for risk
prevention and treatment, including involuntary admission, intra-
muscular medication and physical restraint.
Objectives This study aims to analyze the therapeutic measures
of restriction, according Spanish legislation, article 763 of Civil Pro-
cedure Law, under the condition of a mental disorder.
Method We will proceed to the descriptive statistical analysis of
total cohort of hospital admissions in the Dr. Lopez Ibor Neuropsy-
chiatric Institute in the calendar year 2014 and we will review the
coercive measures to the treatment of those patients who have
decline of the ability to provide informed consent.
Results Of the cohort of income, 10.5% has been involuntary
admission, 51% men versus 49% women. Forty-one percent of
patients have been diagnosed with schizophrenia, schizotypal and
delusional disorder; the other 30% with affective disorders (21%
bipolar disorder or manic disorder); and the 12.2% with disorders
of adult personality and behaviour. Eighteen percent have needed
intra-muscular medication and physical restraint.
Conclusions The proportion of patients with decline of the
decisional-making capacity is less than that found in studies in
other countries of the European Union. The involuntary commit-
ment is more frequently associated with severe mental disorders
and the use of restrictive measures is associated to situations of
danger to the patient or others.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW272
Not just ‘callous-unemotional’:
Psychopathic traits are associated
with emotion dysregulation
dimensions
P. Velotti ∗, M. D’aguanno , C. Garofalo , G. Rogier
1 University of Genoa, Educational Sciences, Psychology Unit, Genova,
Italy
2 University Sapienza, Psychology, Rome, Italy
3 Tilburg University, psychology, Tilburg, Netherlands
∗ Corresponding author.
Introduction Historically, psychopathic individuals have mainly
been described as characterized by pervasive callous-unemotional
traits, with dramatic implications for clinical and forensic prac-
tices – such as the tendency to deem psychopathic individuals as
untreatable. However, recent evidence with community samples
have highlighted that psychopathic traits may be in fact related
to emotion dysregulation rather than being the mere reflection of
an underlying ‘unemotionality’. Yet, it is no clear if this association
extends to populationswithmore severe forms of psychopathy (i.e.,
offenders).
Objectives We wanted to replicate previous evidence of an asso-
ciation between emotion dysregulation and psychopathic traits in
a sample of incarcerated offenders.