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S208

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348

aggression protocol in their hospitals, we think that a prevention

and supporting guideline should be design for improve this preva-

lent situation.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.387

EW270

Abnormal amygdala functional

connectivity during an fMRI

expectancy task in pedophilia

I. Ristow

1 ,

, S . L

i

2 , L.R

. Demenescu

2 , H.

Walter

3 , K. B

eier

4 ,

T. Kruger

5

, B. Schiffer

6

, J. Ponseti

7

, M. Walter

2

1

Magdeburg, Germany

2

CANLAB Magdeburg, Department of Psychiatry, Magdeburg,

Germany

3

Clinic for Psychiatry and Psychotherapy, Clinic for Psychiatry and

Psychotherapy, Berlin, Germany

4

Institute for Sexual Medicine and Sexual Science, Institute for Sexual

Medicine and Sexual Science, Berlin, Germany

5

Research Group Clinical Psychology and Sexual Medicine, Center for

Mental Health, Clinic for Psychiatry, Sociopsychiatry and

Psychotherapy, Hannover, Germany

6

Institute for Forensic Psychiatry of the University Duisburg-Essen,

Institute for Forensic Psychiatry of the University Duisburg-Essen,

Essen, Germany

7

Institute for Sexualmedicine and Forensic Psychiatry and

Psychotherapy, Institute for Sexualmedicine and Forensic Psychiatry

and Psychotherapy, Kiel, Germany

Corresponding author.

Introduction

Pedophilia is a disorder where sexual preferences

of adults are directed towards children. This disorder impacts soci-

ety with 1–2 out of every 10 children being sexually approached

by an adult, often resulting in prolonged negative psychological

effects. Prior research reported structural and functional amygdala

alterations in pedophilia. As the neurophenomenological model of

sexual arousal suggests the importance of the amygdala in the emo-

tional component, we focused on amygdala functional connectivity

in pedophilia.

Aims

To investigate amygdala functional connectivity (FC) mod-

ulated by expectancy and salient stimuli in pedophilic patients.

Methods

Thirteen pedophilic patients and 13 matched healthy

controls underwent a salience expectancy task in a 7T ultra

high fMRI study. Subjects perceived pictures of naked adults and

children. Half of the pictures were preceded by an expectancy

cue. Participants were instructed to actively expect the pic-

ture depending on the cue. We conducted psychophysiological

analysis (PPI) to examine amygdala FC changes in two amyg-

dala sub-regions for child/adult stimuli during the expectancy

period and the visual stimuli consummation period using as seed

regions the basolateral (BLA) and central nucleus of the amygdala

(CeA).

Results

Healthy controls, relative to patients showed significant

stronger left CeA to right post-central gyrus FC during expectancy

of adult > child picture. For picture condition (adult > child picture)

we found significant stronger left CeA to left dorsolateral prefrontal

cortex FC in patients compared to healthy controls.

Conclusion

These findings add to the recent literature by indi-

cating that amygdala dysfunctional connectivity is involved in

development of deviant sexual behavior.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.388

EW271

Restrictive measures in psychiatry

M. Rodríguez Merino

, J.J. Arechederra Aranzadi ,

M.I. López-Ibor Alcocer

Dr. López Ibor Neuropsychiatric Institute, Psychiatry, Madrid, Spain

Corresponding author.

Introduction

Informed consent is guarantor of the three princi-

ples that guide the professional activity of physicians concretely,

information, comprehension and volunteerism, based on bioethi-

cal values of autonomy, non-maleficence, beneficence and justice.

Psychopathological alterations undermine the capacity to con-

sent treatment, requiring, sometimes, restrictive measures for risk

prevention and treatment, including involuntary admission, intra-

muscular medication and physical restraint.

Objectives

This study aims to analyze the therapeutic measures

of restriction, according Spanish legislation, article 763 of Civil Pro-

cedure Law, under the condition of a mental disorder.

Method

We will proceed to the descriptive statistical analysis of

total cohort of hospital admissions in the Dr. Lopez Ibor Neuropsy-

chiatric Institute in the calendar year 2014 and we will review the

coercive measures to the treatment of those patients who have

decline of the ability to provide informed consent.

Results

Of the cohort of income, 10.5% has been involuntary

admission, 51% men versus 49% women. Forty-one percent of

patients have been diagnosed with schizophrenia, schizotypal and

delusional disorder; the other 30% with affective disorders (21%

bipolar disorder or manic disorder); and the 12.2% with disorders

of adult personality and behaviour. Eighteen percent have needed

intra-muscular medication and physical restraint.

Conclusions

The proportion of patients with decline of the

decisional-making capacity is less than that found in studies in

other countries of the European Union. The involuntary commit-

ment is more frequently associated with severe mental disorders

and the use of restrictive measures is associated to situations of

danger to the patient or others.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.389

EW272

Not just ‘callous-unemotional’:

Psychopathic traits are associated

with emotion dysregulation

dimensions

P. Velotti

1 ,

, M. D’aguanno

2

, C. Garofalo

3

, G. Rogier

2

1

University of Genoa, Educational Sciences, Psychology Unit, Genova,

Italy

2

University Sapienza, Psychology, Rome, Italy

3

Tilburg University, psychology, Tilburg, Netherlands

Corresponding author.

Introduction

Historically, psychopathic individuals have mainly

been described as characterized by pervasive callous-unemotional

traits, with dramatic implications for clinical and forensic prac-

tices – such as the tendency to deem psychopathic individuals as

untreatable. However, recent evidence with community samples

have highlighted that psychopathic traits may be in fact related

to emotion dysregulation rather than being the mere reflection of

an underlying ‘unemotionality’. Yet, it is no clear if this association

extends to populationswithmore severe forms of psychopathy (i.e.,

offenders).

Objectives

We wanted to replicate previous evidence of an asso-

ciation between emotion dysregulation and psychopathic traits in

a sample of incarcerated offenders.