European Psychiatry - Volume 33 - March 2016

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S790 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
entering university, however, few treatment options are available.
The aim of this study is to investigate the effectiveness of group
therapy in university students with ASD.
Methods A one-group, pre-intervention-post-intervention
design was adapted for this study. All patients with ASD were
recruited from Shizuoka University. The group therapy programs
consisted of cognitive behavioral therapy and recreational activity.
Outcome measures were Beck Depression Inventory-Second
Edition, Quality of Life Inventory, State Trait Anxiety Inventory and
Rosenberg Self-Esteem Scale.
Results There were 14 participants, 7 males and 7 females. Their
ages were from 19-years-old to 23-years-old. All participants had
over 80% of attendance in the six-month group therapy.
Conclusions These preliminary results suggest that the group
therapy can improve symptoms of depression and anxiety for some
students with ASD. More research is needed to draw more sturdy
conclusions, especially with respect to improvements in quality of
life.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1386
Disruptive behaviour’s treatment with
paliperidone in autistic disorder:
Review and case report
M. García Moreno ∗, A. De Cós Milas , L. Beatobe Carre˜no ,
B. Poza Cano
1 Hospital Universitario Puerta de Hierro Majadahonda, CSM
Majadahonda, Madrid, Spain
2 Hospital Universitario de Móstoles, CSM Móstoles, Madrid, Spain
3 Hospital Universitario El Escorial, CE San Carlos El Escorial, Madrid,
Spain
∗ Corresponding author.
Introduction Autistic disorder (AD) is a neuropsychiatric disor-
der that often presents significant disruptive symptoms such as
irritability, aggression and self-injury in addition to impairment of
social skills and communication. These symptoms interfere both
individuals with AD and their families and social environment.
Objective Show paliperidone effect in behavioural symptoms in
AD.
Methods Literature review about behavioural symptoms in AD
and paliperidone effect in its treatment, followed by a case report of
clinical improvement after treatment with paliperidone in a patient
with autism. Agitation subscaleAberrant Behavior Checklist (ABC-I)
scores was compared prior and 4 weeks after paliperidone treat-
ment, and clinical improvement was assessed with Clinical Global
Impression-Improvement Scale (CGI-I).
Results Although risperidone has been one of the most stud-
ied atypical antipsychotic to treat this symptoms, its use should
be limited in order to avoid extrapyramidal and metabolic symp-
toms. Paliperidone – the major metabolite of risperidone – has
shown effectiveness in the treatment of behavioral symptoms in
patientswith autism, even in subjectswith a prior ineffective trial of
risperidone. Our patient, 21-years-oldmale with AD and significant
disruptive symptoms was treated with paliperidone 9mg/day. We
observed a 20-points reduction in ABC-I scores 4 weeks later, with
most significant improvement in items like auto-agression, het-
eroaggressivity, irritability and slams. CGI-I scores showed a much
better improvement, and no significant adverse effects appeared.
Conclusions Paliperidone is an effective and safe treatment in
behavioral symptoms associated to AD, with reduction in ABC-I
subscale scores. More studies are needed to confirm our data.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1387
Does community care works?
Evaluate the effectiveness of mental
health services
M. Giacomin
Psychiatrist Director of Semiresidential Day Center in Mental Health
Center of Villorba (Tv), Italy
Introduction Improving quality require the capability to evaluate
clinical and operational processes and improve patients outcomes.
Just in the view of evidence-based practise (EBP) it’s used HONOS
rating Scale, adopted since May 2012, by Mental Health Center of
Villorba (Treviso-Italy) There are 3 package treatments: rehabili-
tative, territorial and clinical.
Objectives To identify which variables are positively correlated
to HONOS improvement in patients group who frequented Mental
Health Centre along 36 months. All patients present severe mental
illness.
Aims Evaluate the effectiveness of interventions and correlate
to treatment package and individual feature. Analyze treatment
process for quality improvement.
Method A psychiatric team (4 nurses, 1 psychiatrist) adminis-
tered Honos Rating Scale along 3 years: on starting point and 6,
12 and 36 months later: T 0,1,2,3,4. Patients are also described
by diagnosis, mental, social and autonomy skill, time, utilization of
MHC and anagraphic information.
Results All 15 groups’ patients realize lower scoring, after 36
months’ treatment. Seven have got reliable improvement (i.e. = > 8-
point lowering T3–T4) and positively correlatewith: (1) 36 months’
treatment, at 12 months in rehabilitative Package; (2) days in
residential/semi-residential community from 82 to 311 days.
Related tables are included in paper.
Discussion and conclusion HONOS score correlates directly with
clinical and riabilitation improvement, i.e. mental, social capacity,
and personal autonomy. It needs more investigation to clear which
other factors are involved with improvement.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EV1388
Diagnosis and treatment of ADHD in
young adults
C. Glod
Merrimack College, Academic Affairs, North Andover, USA
Introduction ADHD is one of the most common psychiatric disor-
ders, affecting 6–10% of children. Recent studies have shown that
the illness persists into adolescence and adulthood.
Objectives The purpose of this session is to review the state of
the science of the diagnosis and treatment of ADHD in young adults
and college students. This population poses unique developmental
challenges in evaluation of symptoms and adherence to treatment.
Aims The aim of this presentation is to promote a better under-
standing of the differential diagnosis and effective treatment
options specific to this age group.
Methods Review of the literature.
Results Young adults diagnosedwith ADHD in childhood demon-
strate symptoms of inattention and hyperactivity that continue.
In addition, this age group may present for the first time with
previously undiagnosed symptoms that interfere with functioning.
Further complicating evaluation and treatment may be the emer-
gence ofmooddisorders or alcohol/substance abuse. Left untreated,
ADHD symptoms affect functioning in several key areas including
self-esteem, repeated academic failures, poor occupational per-
formance, propensity for motor vehicle incidents, instability in
relationships, alcohol/substancemisuse and abuse, and overall suc-
cessful transition to adulthood. Psychopharmacological studies of