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S662

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

late onset psychosis includes organic and mental precipitants in its

differential diagnosis.

Objectives

To present a case of late onset schizophrenia.

Methods

Medline search and review of the clinical history and

the related literature.

Results

We present the case of a 71-year-oldwomanwith organic

medical history of rectumadenocarcinoma in 2008 that underwent

radiotherapy, chemotherapy and surgical resection with success-

ful results. According to the psychiatric history, this patient has

needed two admissions to the psychiatry ward, the first of them

in 2012, (when the delusional symptoms started), due to deregu-

lated behaviour in relation to persecutory delusions and auditory

pseudo-hallucinations. In 2012, she was diagnosed with late onset

schizophrenia. Blood tests (hemograme, biochemistry) and brain

image were normal. Despite treatment with oral amisulpride and

oral paliperidone and due to low compliance, delusional symptoms

have remained. We started treatment with long-acting injectable

papliperidone 75mg/28 days having reached clinical stability.

Conclusions

Late onset psychosis is due to a wide range of clinical

conditions. In this case, our patient had no organic precipitants. The

evolution and presentation of delusional symptoms in this patient

made us think of late onset schizophrenia as main diagnosis.

Keywords

“Schizophrenia” ;“Psychosis” ;“Late onset

schizophrenia”

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Further reading

Colijn MA et al. Psychosis in later life: a review and update. Harv

Rev Psychiatry 2015;23(5):354-67.

Reinhard MM. Late-life psychosis: diagnosis and treatment. Curr

Psychiatry Rep 2015;17(2):1.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1963

EV979

Major depressive disorder with

psychotic symptoms in elderly. A case

report

J.M. Hernández Sánchez

1 ,

, M .C

. Cancino Botello

2 ,

M.F. Molina Lopez

2

, M.Á. Canseco Navarro

2

, S. Arnés González

3

,

M. Mu˜noz Carril

3

, J.A. Monzó

4

1

Valencia, Spain

2

Hospital General de Valencia, Psychiatry, Valencia, Spain

3

Hospital General de Valencia, Emergency Medicine, Valencia, Spain

4

Hospital General de Valencia, Internal Medicine, Valencia, Spain

Corresponding author.

Introduction

The proportion of elderly people and affective syn-

dromes aremore andmore common indeveloped countries. Elderly

people have physiological conditions that may limit our interven-

tion.

Objectives

To present a case of a major depressive disorder with

psychotic symptoms in a 72-year-old woman.

Methods

Medline search and review of the clinical history and

the related literature.

Results

We present the case of a 72-year-old woman with psy-

chiatric history of a major depressive disorder 14 years ago with

ad integrum restitution after pharmacological treatment. In 2015,

our patient was admitted to the psychiatry ward due to major

depressive symptomatology (apathy, anhedonia, global insomnia,

weight loss) that associated mood-congruent delusions (nihilistic,

ruin, guilt, catastrophic) with deregulated behaviour. The patient

was resistant to combined pharmacological treatment with arip-

iprazole, desvenlafaxine, mirtazapine and lorazepam, therefore, we

decided to administer ECT, with successful results after 5 sessions.

Brain tomography, blood and urine testswere normal. Clinical signs

of dementia were not present.

Conclusions

Inpatients with deregulated behaviour; it is impor-

tant to rule out organic causes, especially in elderly, in whom

dementia, brain tumors or metabolic disturbances may simulate

psychiatric syndromes.

Keywords

“Major depressive disorder” ;“Psychosis” ;“Late onset

psychosis”

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Further readings

Colijn MA et al. Psychosis in later life: a review and update. Harv

Rev Psychiatry 2015;23(5):354-67.

Reinhard MM. Late-life psychosis: diagnosis and treatment. Curr

Psychiatry Rep 2015;17(2):1.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1964

EV980

The interpretation of anhedonia in a

structure of affective disorders and

schizophrenia

P. Kananovich

Mental Health Research Center of the Russian Academy of Medical

Sciences, Department of endogenous mental disorders and affective

states, Moscow, Russia

Objective

To identify clinical and psychopathological features of

anhedonia in the framework of affective disorders or schizophre-

nia, as well as patterns of a process, development of the criteria of

differential diagnosis and prognosis.

Material and methods

Using psychopathological method, we

examined 37 patients (average age was 27.6 + 1.2 years).

Results

Itwas studied that anhedonia appears to be a non-specific

symptom, but with differences in terms of its dynamics and charac-

teristics, which are realized in differences regarding to prognostic

significance of the phenomenon. We selected 3 main types of anhe-

donia: an anhedonia in the framework of depression in affective

disorders (1), in the framework of depression at the prodromal

stages of schizophrenia with preservation and further intensifica-

tion its particular components (2), an anhedoniawithout associated

mood disorders (or their minor expression) in the framework of

schizophrenia, registered at initial stage and persisted in the future

(3). In affective pathology, anhedonia was observed in a structure

of a manifest depressive state with its further reduction in remis-

sion. In schizophrenia, anhedonia appeared at prodromal stages

as a structural part of depression or without associated mood dis-

orders, with a following persisting retention of its components at

the later non-manifestation states, suggesting reflection affinity

of anhedonia to schizophrenia. Anhedonia without concomitant

mood disorders in schizophrenia correlated with

ɑ

poorer outcome

and more severe psychotic symptoms.

Conclusions

The presented differences in a structure of anhedo-

nia allow to speak about its correlation with a risk of manifestation

of endogenic pshychosis, the course of illness and its prognosis.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.1965

EV981

Obsessive versus delusional jealousy:

Destruction in a form of creation – A

review

R. Almeida Leite

, E. C

onde , T. Queirós Santos , M. Almeida ,

T. Azevedo Santos , A. Mesquita Figueiredo

Baixo Vouga Hospital Centre, Psychiatry and Mental Health

Department, Aveiro, Portugal

Corresponding author.

Introduction

Jealousy is a complex emotional state and some

degree is considered normal in mature love, but when does it

become destructive in a relationship? There’s a thin line between