European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S615
Head CT-SCAN revealed agenesia of CC. She received the diagnosis
ofManic Episodewithmixed features andwas treatedwith valproic
acid, flurazepam and olanzapine.
Conclusion This case reinforces the fact that changes in CC,
probably due to deficiency in myelination, could have a crucial
importance in the pathophysiology of Bipolar Disorder.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV829
Relationship between corpus
callosum and anterior commeasure
size in brain MRI and human
intelligence
R. Zareii ∗, A. Alaee
1 Shiraz, Iran
2 Mazandaran University of Medical Sciences, Department of
Radiology, Sari, Iran
∗ Corresponding author.
Introduction and aims After Parieto-frontal integration theory of
intelligence, a new area of investigations was began to examine
howperformance networks associatewith structural networks and
the results highlighted the role of brain commissures such as corpus
callosum (CC) and anterior commissure (AC) in intelligence. So we
investigated the relationship between CC and AC size, as the most
important interhemispheric commissure, and intelligence.
Methods and materials Healthy volunteers who their MRI images
lack any pathological entity were chosen. Height, length and thick-
ness of CC and transverse, sagittal and superior-inferior diameter of
AC were acquired on a 1.5-tesla MRI and a T2-weighted sequences.
intelligence quotient(IQ) was measured using the Wechsler intel-
ligence quotient scale too.
Results Our results showed that the length of the CC had a nega-
tive correlation and height of the CC had a positive correlation with
IQ. However, the thickness of genu, body and spleniumof CC did not
show any significant correlation with IQ. Superior-inferior diame-
ter of AC, before and after excluding the effect of age, and sagittal
diameter of AC only after excluding the effect of age, showed a sig-
nificant negative correlation with IQ but no significant correlation
was realized between the transverse diameter of AC and IQ.
Conclusions Based on our findings, at an early age higher
intelligence of the men is because of stronger intrahemispheric
communication and with aging, it is due to interhemispheric
communications through CC. In contrast, it seems that higher intel-
ligence inwomen, resulting fromstronger interactions between the
hemispheres through both AC and CC.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Obsessive-compulsive disorder
EV830
Co-morbid obsessive compulsive and
hypochondriac disorders complicated
by tardive dyskinesia in a Nigerian
man
C. Aghukwa
Bayero University Kano/Aminu Kano Teaching Hospital, Psychiatry,
Kano, Nigeria
Introduction Obsessive-compulsive disorder is a group of disor-
ders with unwanted repetition of either mind or physical acts, or
both actsmanifesting in an insightful sufferer. The pharmacological
treatment of this group of disorders could lead to the use of more
than one class of drug with resulting negative consequences such
as tardive dyskinesia.
Objective The objective was to report a case of obsessive-
compulsive disorder (OCD) with comorbid somatic symptoms that
was complicated by movement disorders.
Method A literature search on related issues was done online
withGoogle Scholar, followed by a chronological report of the index
case.
Result This case presents a 52-year-old man who presented with
intrusive, disturbing, and unreasonable thoughts at the mid ado-
lescent time. Following these were complaints of multiple somatic
symptoms, which the patient labeled with different disease terms.
The illness affected his academic, occupational, social, and mar-
ital role obligations. And lately, in the illness due to underlying
predispositions, developed drug-related movement problems that
worsened his state of handicap.
Conclusion This case attempts to point out the importance
of early detection and cautious use of medications in patients,
who present with OCDs with or without other psychiatric co-
morbidities.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV831
The nose – A case report of body
dysmorphic disorder and a literature
review
C. Agostinho ∗, S. Henriques , I. Coelho
1 Centro Hospitalar Psiquiátrico de Lisboa, Centro Hospitalar
Psiquiátrico de Lisboa, LRS Bobadela, Portugal
2 Centro Hospitalar Psiquiátrico de Lisboa, Centro Hospitalar
Psiquiátrico de Lisboa, Lisboa, Portugal
∗ Corresponding author.
Introduction Body Dysmophic Disorder (BDD) is relatively com-
mon disorder. Patientswith delusional beliefs seemto showgreater
morbidity (more suicidal attempts and drug abuse or dependence)
and less likelihood of receiving treatment.
Objectives and aims In this study, we intended to report a case
of BDD followed in psychiatric consultation from 2 years ago, and
to make a review of the literature, namely presentation, treatment
and prognosis of BDD.
Methods We conducted a description of a BDD case and a
research using “Body Dysmorphic Disorder” keywords on Pubmed.
Results J.F., 45 years old, unemployed, living with his father,
referred to the Psychiatric consultation by his GP. The disorder
started in the adolescence with an excessive preoccupation with
hair loss and nose length, but in early adulthood these concerns
became more important. Around 30 years old he was followed in
Psychiatry but abandoned. Years later he underwent nose plas-
tic surgery. He tried underwent other nose surgeries, but was
refused. He was advised to look for psychiatric care. From the
initial observation I highlight the appearance (thin, with a wig,
adhesive tape connecting the tip of the nose to the forehead
pulling up the nose), delusional ideas regarding the appearance of
the nose, overvalued hypochondriac ideas, and no insight for the
disease. The patient was reluctant in taking psychotropic drugs.
He was referred to day hospital, which he attended with great
irregularity.
Conclusions BDD is a disorder with poor prognosis, especially
when delusional variant is present, probably in relation to the lack
of insight.