European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S549
EV624
“Flakka”: An emerging trend or a
mass media phenomenon? Presence
of alpha-PVP in samples submitted to
a drug checking facility
M. Grifell ∗, P. Quintana , M. Torrens , A. Palma ,
L. Galindo , M. Ventura , I. Fornís , C. Gil , F. Caudevilla ,
M. Farré
1 Parc de salut Mar, Institut de neuropsiquiatria i addiccions (INAD),
Barcelona, Spain
2 Associació Benestar i desenvolupament ABD, Energy Control,
Barcelona, Spain
3 Hospital del mar medical research institute IMIM, Grup de recerca
en addiccions, Barcelona, Spain
4 Institut Català de la Salut (ICS), EAP Raval Sud, Barcelona, Spain
5 Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain
6 Hospital Germans Tries i Pujol IGTP, Farmacología clínica, Badalona,
Spain
∗ Corresponding author.
Introduction New psychoactive substances (NPS) are drugs
that have recently become available, are not worldwide regu-
lated, and often intend to mimic the effect of controlled drugs.
-Pyrrolidinopentiophenone (Alpha-PVP) is a potent stimulant
cathinone that is thought to act inhibiting dopamine and nora-
drenaline reuptake. It has been associated with hallucinations,
psychosis and death.
Objectives To explore the presence of Alpha-PVP from the sam-
ples handled to, and analyzed by energy control.
To determine whether it is a new trend in recreational settings.
Methods All samples presented to energy control were analyzed.
Samples in which alpha-PVP was detected using Gas
Chromatography-Mass Spectrometry were selected for study.
A Google trend analysis was also performed to asses the media
impact of alpha-PVP.
Results From a total of 20,062 samples, 33 contained alpha-PVP
(0.16%). The samples containing alpha-PVP were mostly sold as
such (40%) despite a significant proportion being sold as MDMA
(15%). Google trend analysis showed an abrupt increase of alpha-
PVP searches in 2015 reaching 50% of the MDMA-ones.
Conclusion Our results suggest presence of Alpha-PVP in the drug
market may be increasing, especially as adulterant of other drugs.
Severe side effects might be even more serious considering that a
significant proportion of usersmay ignorewhich substance they are
actually using. However, the total amount of alpha-PVP analyzed
remains small, and does not support the alarming reports published
in media.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV625
Frequent attendance: A clinical and
epidemiological study
S. López-Romeo ∗, G. Ledesma-Iparraguirre
Parc Sanitari Sant Joan de Déu, Psychiatry, Barcelona, Spain
∗ Corresponding author.
Background Frequent attenders (FA) are patients who attend a
health care facility repeatedly. The frequency of frequent atten-
dance at emergencies department has been defined as 4 or more
attendances/annum. FA are few in number but they produce a high
number of attendances.
Aims To determine prevalence of FA, mean attendances/year
generated by FA and frequency of visits by months.
Methods A retrospective study was performed on psychiatry’s
emergency department database from January until December
2013. FA was defined as those with≥ 4 attendances at emergency
services in a year.
Prevalence of FA, attendances’ prevalence, diagnosis’ prevalence,
Mean attendances generated by FA and frequency of visits by
months were analysed.
Results Among 4824 attendances we found 181 FAs (5.98%). Men
represented 50.80% and women 49.20%. FA presented a mean of
6.33 attendances/year, while non-FA presented a mean of 1.29
attendances/year.
In accordance with frequency of visits by months, it was observed
that number of attendances was increased in April andMay, in both
FA and non-FA.
Conclusion Prevalence of FA was 5.98%, FA generated a 23.74% of
attendances. Most prevalent FA’ diagnoses were: anxiety disorder,
personality disorder non-specified and schizophrenia.
FA at emergency department contributes to overcrowd them. For
this reason, it is important to take into account these results to
develop new strategies to improve FA’ attention and prevent its
occurrence.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV626
Patients’ characteristics related with
risk of being restrained in acute
psychiatric hospital in Romania
A. Mihai ∗, M. Crainic , M. Mocan , I. Alexiev , A.P. S˘arm˘aan ,
A. Mihai
1 University of Medicine and Pharmacy “Iuliu Hatieganu”, Medicine,
Cluj-Napoca, Romania
2 Institute of Psychotherapy and Personal Development (IPPD),
Psychology and Psychotherapy, Targu Mures, Romania
3 University of Medicine and Pharmacy Tg Mures, Medical Asistent,
Gh Marinescu 38, Tg Mures, Romania
4 University of Medicine and Pharmacy Tg Mures, Psychiatric
Department, Gh Marinescu 38, Tg Mures, Romania
∗ Corresponding author.
Seclusion and restraining in acute psychiatry wards is used when
patients tend to harm themselves, other patients or staff members.
Seclusion and restraining decision-making is a complex process
based on risk of aggressivity, patient’s diagnosis, history of vio-
lent incidents, staff experience, hospital internal regulations and
national mental health law.
The aim of this study is to evidentiate the patients’ characteris-
tics, which could be predisposed to restraining procedure in acute
psychiatric setting in Romania.
Material and method This is a two years retrospective study
conducted on a total of 1000patients (56.9 females, 43.1males) ran-
domly selected, admitted in acute psychiatric hospital. From these
on 100 patients restraining techniques were applied.
Results and discussions Out of the restrained patients male,
younger usually suffering of personality disorder were more
frequent restrained. Statistical analysis of restrained group charac-
teristics comparing with larger group of the total patients admitted
showed no significant differences between these two groups.
Regressive analysis on different clusters found a higher risk to be
restrained for patients with agitation and recurrent depressive dis-
order, male, from urban area. This study draws attention to the
importance of a good study design and proper methodology.
Conclusion The factors which influence the risk of being
restrained in acute psychiatric setting aremore relatedwith behav-
ior characteristics than diagnosis or demographical items.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.